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Eoin O'Connor
Eoin O'Connor
Scientist, Lab Head, F. Hoffmann-La Roche
在 roche.com 的电子邮件经过验证
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引用次数
引用次数
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Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning
MTC Brown, KR Tan, EC O’Connor, I Nikonenko, D Muller, C Lüscher
Nature 492 (7429), 452-456, 2012
4042012
Contrasting forms of cocaine-evoked plasticity control components of relapse
V Pascoli, J Terrier, J Espallergues, E Valjent, EC O’Connor, C Lüscher
Nature 509 (7501), 459-464, 2014
3942014
Accumbal D1R neurons projecting to lateral hypothalamus authorize feeding
EC O’Connor, Y Kremer, S Lefort, M Harada, V Pascoli, C Rohner, ...
Neuron 88 (3), 553-564, 2015
2762015
Homeostasis meets motivation in the battle to control food intake
CR Ferrario, G Labouèbe, S Liu, EH Nieh, VH Routh, S Xu, EC O'Connor
Journal of Neuroscience 36 (45), 11469-11481, 2016
2572016
The predictive validity of the rat self-administration model for abuse liability
EC O’Connor, K Chapman, P Butler, AN Mead
Neuroscience & Biobehavioral Reviews 35 (3), 912-938, 2011
2092011
SHANK3 controls maturation of social reward circuits in the VTA
S Bariselli, S Tzanoulinou, C Glangetas, C Prévost-Solié, L Pucci, ...
Nature neuroscience 19 (7), 926-934, 2016
1532016
The α4β2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking …
EC O’Connor, D Parker, H Rollema, AN Mead
Psychopharmacology 208, 365-376, 2010
1282010
Expression of cocaine-evoked synaptic plasticity by GluN3A-containing NMDA receptors
T Yuan, M Mameli, EC O'Connor, PN Dey, C Verpelli, C Sala, ...
Neuron 80 (4), 1025-1038, 2013
1182013
Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons
M Novak, B Halbout, EC O'Connor, JR Parkitna, T Su, M Chai, ...
Journal of Neuroscience 30 (36), 11973-11982, 2010
732010
Synaptic basis of social dysfunction: a focus on postsynaptic proteins linking group‐I m G lu R s with AMPAR s and NMDAR s
EC O'Connor, S Bariselli, C Bellone
European Journal of Neuroscience 39 (7), 1114-1129, 2014
532014
Depression of accumbal to lateral hypothalamic synapses gates overeating
S Thoeni, M Loureiro, EC O’Connor, C Lüscher
Neuron 107 (1), 158-172. e4, 2020
472020
Tramadol acts as a weak reinforcer in the rat self-administration model, consistent with its low abuse liability in humans
EC O'Connor, AN Mead
Pharmacology Biochemistry and Behavior 96 (3), 279-286, 2010
372010
The mGluR5 antagonist MTEP dissociates the acquisition of predictive and incentive motivational properties of reward-paired stimuli in mice
EC O'connor, HS Crombag, AN Mead, DN Stephens
Neuropsychopharmacology 35 (8), 1807-1817, 2010
332010
Modeling Appetitive Pavlovian‐Instrumental Interactions in Mice
EC O'Connor, DN Stephens, HS Crombag
Current Protocols in Neuroscience 53 (1), 8.25. 1-8.25. 27, 2010
112010
Striatum-projecting prefrontal cortex neurons support working memory maintenance
M Wilhelm, Y Sych, A Fomins, JL Alatorre Warren, C Lewis, ...
Nature Communications 14 (1), 7016, 2023
72023
A minimal metadata set (MNMS) to repurpose nonclinical in vivo data for biomedical research
A Moresis, L Restivo, S Bromilow, G Flik, G Rosati, F Scorrano, M Tsoory, ...
Lab animal 53 (3), 67-79, 2024
22024
Advancements in the use of xenopus oocytes for modelling neurological disease for novel drug discovery
EC O’Connor, K Kambara, D Bertrand
Expert Opinion on Drug Discovery 19 (2), 173-187, 2024
22024
Selective and brain-penetrant hcn1 inhibitors reveal links between synaptic integration, cortical function, and working memory
E Harde, M Hierl, M Weber, D Waiz, R Wyler, JY Wach, R Haab, ...
Cell Chemical Biology 31 (3), 577-592. e23, 2024
12024
Analysis of behavioral flow resolves latent phenotypes
LM von Ziegler, FK Roessler, O Sturman, R Waag, M Privitera, SN Duss, ...
bioRxiv, 2023.07. 27.550778, 2023
12023
Alkynyl-(heteroaryl)-carboxamide hcn1 inhibitors
B Bartels, AL Dupont, BJ Hall, JY Wach, C Schnider, P Schnider, ...
US Patent App. 17/830,215, 2022
12022
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