Activation of β‐catenin signaling in articular chondrocytes leads to osteoarthritis‐like phenotype in adult β‐catenin conditional activation mice M Zhu, D Tang, Q Wu, S Hao, M Chen, C Xie, RN Rosier, RJ O'Keefe, ... Journal of Bone and Mineral Research 24 (1), 12-21, 2009 | 589 | 2009 |
Inhibition of β‐catenin signaling in articular chondrocytes results in articular cartilage destruction M Zhu, M Chen, M Zuscik, Q Wu, YJ Wang, RN Rosier, RJ O'Keefe, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 329 | 2008 |
Regulation of chondrogenesis and chondrocyte differentiation by stress MJ Zuscik, MJ Hilton, X Zhang, D Chen, RJ O’Keefe The Journal of clinical investigation 118 (2), 429-438, 2008 | 322 | 2008 |
Targeting the gut microbiome to treat the osteoarthritis of obesity EM Schott, CW Farnsworth, A Grier, JA Lillis, S Soniwala, GH Dadourian, ... JCI insight 3 (8), 2018 | 242 | 2018 |
RBPjκ-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development Y Dong, AM Jesse, A Kohn, LM Gunnell, T Honjo, MJ Zuscik, RJ O'Keefe, ... Development 137 (9), 1461-1471, 2010 | 202 | 2010 |
Reduced COX‐2 expression in aged mice is associated with impaired fracture healing AA Naik, C Xie, MJ Zuscik, P Kingsley, EM Schwarz, H Awad, R Guldberg, ... Journal of Bone and Mineral Research 24 (2), 251-264, 2009 | 200 | 2009 |
Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis ER Sampson, MJ Hilton, Y Tian, D Chen, EM Schwarz, RA Mooney, ... Science translational medicine 3 (101), 101ra93-101ra93, 2011 | 193 | 2011 |
Smad3‐deficient chondrocytes have enhanced BMP signaling and accelerated differentiation TF Li, M Darowish, MJ Zuscik, D Chen, EM Schwarz, RN Rosier, H Drissi, ... Journal of Bone and Mineral Research 21 (1), 4-16, 2006 | 183 | 2006 |
High-fat diet accelerates progression of osteoarthritis after meniscal/ligamentous injury RA Mooney, ER Sampson, J Lerea, RN Rosier, MJ Zuscik Arthritis research & therapy 13, 1-10, 2011 | 171 | 2011 |
Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency JJ Carmouche, JE Puzas, X Zhang, P Tiyapatanaputi, DA Cory-Slechta, ... Environmental health perspectives 113 (6), 749-755, 2005 | 163 | 2005 |
Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-β delays hypertrophy and PGE2 inhibits terminal differentiation X Zhang, N Ziran, JJ Goater, EM Schwarz, JE Puzas, RN Rosier, M Zuscik, ... Bone 34 (5), 809-817, 2004 | 163 | 2004 |
Induction of an osteoarthritis‐like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice Q Wu, KO Kim, ER Sampson, D Chen, H Awad, T O'Brien, JE Puzas, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 146 | 2008 |
Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis H Drissi, M Zuscik, R Rosier, R O’Keefe Molecular Aspects of Medicine 26 (3), 169-179, 2005 | 146 | 2005 |
ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development D Zhang, EM Schwarz, RN Rosier, MJ Zuscik, JE Puzas, RJ O'Keefe Journal of Bone and Mineral Research 18 (9), 1593-1604, 2003 | 146 | 2003 |
Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2 M Usui, L Xing, H Drissi, M Zuscik, R O'Keefe, D Chen, BF Boyce Journal of Bone and Mineral Research 23 (3), 314-325, 2008 | 144 | 2008 |
Overexpression of the α1B-adrenergic receptor causes apoptotic neurodegeneration: multiple system atrophy MJ Zuscik, S Sands, SA Ross, DJJ Waugh, RJ Gaivin, D Morilak, ... Nature medicine 6 (12), 1388-1394, 2000 | 144 | 2000 |
Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus ML Brown, K Yukata, CW Farnsworth, DG Chen, H Awad, MJ Hilton, ... PloS one 9 (6), e99656, 2014 | 128 | 2014 |
Erythropoietin accelerates functional recovery after peripheral nerve injury JC Elfar, JA Jacobson, JE Puzas, RN Rosier, MJ Zuscik JBJS 90 (8), 1644-1653, 2008 | 125 | 2008 |
Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway TF Li, Y Dong, AM Ionescu, RN Rosier, MJ Zuscik, EM Schwarz, ... Experimental Cell Research 299 (1), 128-136, 2004 | 124 | 2004 |
High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment L Shu, E Beier, T Sheu, H Zhang, MJ Zuscik, EJ Puzas, BF Boyce, ... Calcified tissue international 96, 313-323, 2015 | 123 | 2015 |