Retroviral intasome assembly and inhibition of DNA strand transfer S Hare, SS Gupta, E Valkov, A Engelman, P Cherepanov Nature 464 (7286), 232-236, 2010 | 791 | 2010 |
A molecular mechanism for bacterial susceptibility to zinc CA McDevitt, AD Ogunniyi, E Valkov, MC Lawrence, B Kobe, AG McEwan, ... PLoS pathogens 7 (11), e1002357, 2011 | 462 | 2011 |
Structural and functional analysis of a plant resistance protein TIR domain reveals interfaces for self-association, signaling, and autoregulation M Bernoux, T Ve, S Williams, C Warren, D Hatters, E Valkov, X Zhang, ... Cell host & microbe 9 (3), 200-211, 2011 | 396 | 2011 |
Improved molecular replacement by density-and energy-guided protein structure optimization F DiMaio, TC Terwilliger, RJ Read, A Wlodawer, G Oberdorfer, U Wagner, ... Nature 473 (7348), 540-543, 2011 | 265 | 2011 |
A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75 S Hare, MC Shun, SS Gupta, E Valkov, A Engelman, P Cherepanov PLoS pathogens 5 (1), e1000259, 2009 | 178 | 2009 |
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection E Valkov, A Stamp, F DiMaio, D Baker, B Verstak, P Roversi, S Kellie, ... Proceedings of the National Academy of Sciences 108 (36), 14879-14884, 2011 | 156 | 2011 |
Functional and structural characterization of the integrase from the prototype foamy virus E Valkov, SS Gupta, S Hare, A Helander, P Roversi, M McClure, ... Nucleic acids research 37 (1), 243-255, 2009 | 151 | 2009 |
The structures of eIF4E-eIF4G complexes reveal an extended interface to regulate translation initiation S Grüner, D Peter, R Weber, L Wohlbold, MY Chung, O Weichenrieder, ... Molecular cell 64 (3), 467-479, 2016 | 128 | 2016 |
Targeting Protein-Protein Interactions and Fragment-Based Drug Discovery. E Valkov, T Sharpe, M Marsh, S Greive, M Hyvönen Topics in current chemistry, 2011 | 124 | 2011 |
Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation T Raisch, CT Chang, Y Levdansky, S Muthukumar, S Raunser, E Valkov Nature Communications 10 (1), 3173, 2019 | 85 | 2019 |
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression D Peter, R Weber, F Sandmeir, L Wohlbold, S Helms, P Bawankar, ... Genes & Development 31 (11), 1147-1161, 2017 | 82 | 2017 |
Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export D Jani, E Valkov, M Stewart Nucleic acids research 42 (10), 6686-6697, 2014 | 81 | 2014 |
Structural basis for P an3 binding to P an2 and its function in mRNA recruitment and deadenylation J Wolf, E Valkov, MD Allen, B Meineke, Y Gordiyenko, SH McLaughlin, ... The EMBO journal 33 (14), 1514-1526, 2014 | 79 | 2014 |
Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB M Alaidarous, T Ve, LW Casey, E Valkov, DJ Ericsson, MO Ullah, ... Journal of Biological Chemistry 289 (2), 654-668, 2014 | 78 | 2014 |
VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins JD Swarbrick, DJ Shaw, S Chhabra, R Ghai, E Valkov, SJ Norwood, ... PLoS One 6 (5), e20420, 2011 | 70 | 2011 |
De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans CA Morrow, E Valkov, A Stamp, EWL Chow, IR Lee, A Wronski, ... Public Library of Science 8 (10), e1002957, 2012 | 69 | 2012 |
Distinct modes of recruitment of the CCR4–NOT complex by Drosophila and vertebrate Nanos T Raisch, D Bhandari, K Sabath, S Helms, E Valkov, O Weichenrieder, ... The EMBO journal 35 (9), 974-990, 2016 | 67 | 2016 |
Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation E Valkov, S Muthukumar, CT Chang, S Jonas, O Weichenrieder, ... Nature structural & molecular biology 23 (6), 574-579, 2016 | 58 | 2016 |
The principal mRNA nuclear export factor NXF1: NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA S Aibara, J Katahira, E Valkov, M Stewart Nucleic acids research 43 (3), 1883-1893, 2015 | 56 | 2015 |
4EHP and GIGYF1/2 mediate translation-coupled messenger RNA decay R Weber, MY Chung, C Keskeny, U Zinnall, M Landthaler, E Valkov, ... Cell reports 33 (2), 2020 | 50 | 2020 |