Toll-like receptor 2–mediated NF-κB activation requires a Rac1-dependent pathway L Arbibe, JP Mira, N Teusch, L Kline, M Guha, N Mackman, PJ Godowski, ... Nature immunology 1 (6), 533-540, 2000 | 825 | 2000 |
Rho kinase, a promising drug target for neurological disorders BK Mueller, H Mack, N Teusch Nature reviews Drug discovery 4 (5), 387-398, 2005 | 805 | 2005 |
Cdc42 regulates cofilin during the establishment of neuronal polarity BK Garvalov, KC Flynn, D Neukirchen, L Meyn, N Teusch, X Wu, ... Journal of Neuroscience 27 (48), 13117-13129, 2007 | 315 | 2007 |
Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo P Lingor, N Teusch, K Schwarz, R Mueller, H Mack, M Bähr, BK Mueller Journal of neurochemistry 103 (1), 181-189, 2007 | 281 | 2007 |
5-substituted indazoles as kinase inhibitors I Akritopoulou-Zanze, BD Wakefield, H Mack, SC Turner, AF Gasiecki, ... US Patent 8,648,069, 2014 | 222 | 2014 |
Controlling variables for the uptake of atmospheric carbonyl sulfide by soil J Kesselmeier, N Teusch, U Kuhn Journal of Geophysical Research: Atmospheres 104 (D9), 11577-11584, 1999 | 135 | 1999 |
Role of Rho kinase pathway in chondroitin sulfate proteoglycan‐mediated inhibition of neurite outgrowth in PC12 cells SM Gopalakrishnan, N Teusch, C Imhof, MHM Bakker, M Schurdak, ... Journal of neuroscience research 86 (10), 2214-2226, 2008 | 89 | 2008 |
The low molecular weight GTPase RhoA and atypical protein kinase Cζ are required for TLR2-mediated gene transcription N Teusch, E Lombardo, J Eddleston, UG Knaus The Journal of Immunology 173 (1), 507-514, 2004 | 67 | 2004 |
A synthetic glycopeptide vaccine for the induction of a monoclonal antibody that differentiates between normal and tumor mammary cells and enables the diagnosis of human … B Palitzsch, N Gaidzik, N Stergiou, S Stahn, S Hartmann, B Gerlitzki, ... Angewandte Chemie International Edition 55 (8), 2894-2898, 2016 | 66 | 2016 |
Inhibitors of Rho‐kinase modulate amyloid‐β (Aβ) secretion but lack selectivity for Aβ42 S Leuchtenberger, MP Kummer, T Kukar, E Czirr, N Teusch, SA Sagi, ... Journal of neurochemistry 96 (2), 355-365, 2006 | 48 | 2006 |
New colchicine-derived triazoles and their influence on cytotoxicity and microtubule morphology P Thomopoulou, J Sachs, N Teusch, A Mariappan, J Gopalakrishnan, ... ACS Medicinal Chemistry Letters 7 (2), 188-191, 2016 | 44 | 2016 |
The marine natural product pseudopterosin blocks cytokine release of triple-negative breast cancer and monocytic leukemia cells by inhibiting NF-κB signaling J Sperlich, R Kerr, N Teusch Marine drugs 15 (9), 262, 2017 | 32 | 2017 |
Azaphilones from the Red Sea Fungus Aspergillus falconensis DH El-Kashef, FS Youssef, R Hartmann, TO Knedel, C Janiak, W Lin, ... Marine Drugs 18 (4), 204, 2020 | 30 | 2020 |
Selective inhibitors of glutathione transferase P1 with trioxane structure as anticancer agents M Bräutigam, N Teusch, T Schenk, M Sheikh, RZ Aricioglu, SH Borowski, ... ChemMedChem 10 (4), 629-639, 2015 | 29 | 2015 |
Polyketides from the marine-derived fungus Aspergillus falconensis: In silico and in vitro cytotoxicity studies DH El-Kashef, FS Youssef, I Reimche, N Teusch, WEG Mueller, W Lin, ... Bioorganic & Medicinal Chemistry 29, 115883, 2021 | 23 | 2021 |
Synthesis and cytotoxic activities of goniothalamins and derivatives A Weber, K Döhl, J Sachs, ACM Nordschild, D Schröder, A Kulik, ... Bioorganic & medicinal chemistry 25 (22), 6115-6125, 2017 | 22 | 2017 |
Novel 3, 4-dihydroisocoumarins inhibit human P-gp and BCRP in multidrug resistant tumors and demonstrate substrate inhibition of yeast Pdr5 J Sachs, K Döhl, A Weber, M Bonus, F Ehlers, E Fleischer, A Klinger, ... Frontiers in pharmacology 10, 400, 2019 | 19 | 2019 |
Identification and optimization of substituted 5-aminopyrazoles as potent and selective adenosine A1 receptor antagonists N Griebenow, L Bärfacker, H Meier, D Schneider, N Teusch, K Lustig, ... Bioorganic & medicinal chemistry letters 20 (19), 5891-5894, 2010 | 19 | 2010 |
Azaphilone Derivatives from the Fungus Coniella fragariae Inhibit NF-κB Activation and Reduce Tumor Cell Migration H Yu, J Sperlich, A Mandi, T Kurtán, H Dai, N Teusch, ZY Guo, K Zou, ... Journal of natural products 81 (11), 2493-2500, 2018 | 18 | 2018 |
Pseudopterosin inhibits proliferation and 3D invasion in triple-negative breast cancer by agonizing glucocorticoid receptor alpha J Sperlich, N Teusch Molecules 23 (8), 1992, 2018 | 18 | 2018 |