Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth L Zhang, S Zhang, J Yao, FJ Lowery, Q Zhang, WC Huang, P Li, M Li, ... Nature 527 (7576), 100-104, 2015 | 1189 | 2015 |
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer S Krishna, FJ Lowery, AR Copeland, E Bahadiroglu, R Mukherjee, L Jia, ... Science 370 (6522), 1328-1334, 2020 | 356 | 2020 |
mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer G Cafri, JJ Gartner, T Zaks, K Hopson, N Levin, BC Paria, MR Parkhurst, ... The Journal of clinical investigation 130 (11), 5976-5988, 2020 | 289 | 2020 |
Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers FJ Lowery, S Krishna, R Yossef, NB Parikh, PD Chatani, N Zacharakis, ... Science 375 (6583), 877-884, 2022 | 226 | 2022 |
Unique neoantigens arise from somatic mutations in patients with gastrointestinal cancers MR Parkhurst, PF Robbins, E Tran, TD Prickett, JJ Gartner, L Jia, G Ivey, ... Cancer discovery 9 (8), 1022-1035, 2019 | 216 | 2019 |
14-3-3ζ turns TGF-β’s function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2 J Xu, S Acharya, O Sahin, Q Zhang, Y Saito, J Yao, H Wang, P Li, L Zhang, ... Cancer cell 27 (2), 177-192, 2015 | 188 | 2015 |
Brain metastasis: Unique challenges and open opportunities FJ Lowery, D Yu Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1867 (1), 49-57, 2017 | 165 | 2017 |
SRC family kinases as novel therapeutic targets to treat breast cancer brain metastases S Zhang, WC Huang, L Zhang, C Zhang, FJ Lowery, Z Ding, H Guo, ... Cancer research 73 (18), 5764-5774, 2013 | 122 | 2013 |
A phenotypic signature that identifies neoantigen-reactive T cells in fresh human lung cancers K Hanada, C Zhao, R Gil-Hoyos, JJ Gartner, C Chow-Parmer, FJ Lowery, ... Cancer Cell 40 (5), 479-493. e6, 2022 | 96 | 2022 |
Antigen experienced T cells from peripheral blood recognize p53 neoantigens P Malekzadeh, R Yossef, G Cafri, BC Paria, FJ Lowery, M Jafferji, ... Clinical Cancer Research 26 (6), 1267-1276, 2020 | 96 | 2020 |
High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology VK Anagnostou, FJ Lowery, V Zolota, V Tzelepi, A Gopinath, C Liceaga, ... BMC cancer 10, 1-11, 2010 | 90 | 2010 |
Adoptive cellular therapy with autologous tumor-infiltrating lymphocytes and T-cell receptor–engineered T cells targeting common p53 neoantigens in human solid tumors SP Kim, NR Vale, N Zacharakis, S Krishna, Z Yu, B Gasmi, JJ Gartner, ... Cancer immunology research 10 (8), 932-946, 2022 | 82 | 2022 |
Sphingosine kinase 1 signaling promotes metastasis of triple-negative breast cancer S Acharya, J Yao, P Li, C Zhang, FJ Lowery, Q Zhang, H Guo, J Qu, ... Cancer research 79 (16), 4211-4226, 2019 | 59 | 2019 |
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade DC Palmer, BR Webber, Y Patel, MJ Johnson, CM Kariya, WS Lahr, ... Med 3 (10), 682-704. e8, 2022 | 47 | 2022 |
Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis SM Saldana, HH Lee, FJ Lowery, YB Khotskaya, W Xia, C Zhang, ... PloS one 8 (9), e73406, 2013 | 40 | 2013 |
Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing YC Lu, Z Zheng, FJ Lowery, JJ Gartner, TD Prickett, PF Robbins, ... Journal for Immunotherapy of Cancer 9 (7), 2021 | 39 | 2021 |
Intracarotid cancer cell injection to produce mouse models of brain metastasis C Zhang, FJ Lowery, D Yu JoVE (Journal of Visualized Experiments), e55085, 2017 | 31 | 2017 |
Growth factor signaling in metastasis: current understanding and future opportunities FJ Lowery, D Yu Cancer and Metastasis Reviews 31, 479-491, 2012 | 28 | 2012 |
Neoantigen identification and response to adoptive cell transfer in anti–PD-1 naïve and experienced patients with metastatic melanoma ST Levi, AR Copeland, S Nah, JS Crystal, GD Ivey, A Lalani, M Jafferji, ... Clinical cancer research 28 (14), 3042-3052, 2022 | 27 | 2022 |
Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy N Levin, BC Paria, NR Vale, R Yossef, FJ Lowery, MR Parkhurst, Z Yu, ... Clinical Cancer Research 27 (18), 5084-5095, 2021 | 27 | 2021 |