Tumor hypoxia regulates immune escape/invasion: influence on angiogenesis and potential impact of hypoxic biomarkers on cancer therapies R Abou Khouzam, K Brodaczewska, A Filipiak, NA Zeinelabdin, S Buart, ... Frontiers in Immunology, 3479, 2021 | 130 | 2021 |
Integrating tumor hypoxic stress in novel and more adaptable strategies for cancer immunotherapy R Abou Khouzam, HV Goutham, RF Zaarour, AN Chamseddine, A Francis, ... Seminars in cancer biology 65, 140-154, 2020 | 65 | 2020 |
The effect of hypoxia and hypoxia-associated pathways in the regulation of antitumor response: friends or foes? R Abou Khouzam, RF Zaarour, K Brodaczewska, B Azakir, GH Venkatesh, ... Frontiers in Immunology 13, 2022 | 37 | 2022 |
An eight-gene hypoxia signature predicts survival in pancreatic cancer and is associated with an immunosuppressed tumor microenvironment R Abou Khouzam, SP Rao, GH Venkatesh, NA Zeinelabdin, S Buart, ... Frontiers in immunology 12, 2021 | 34 | 2021 |
Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition A Engelsen, M Lotsberg, R Abou Khouzam, J Thiery, J Lorens, S Chouaib, ... Frontiers in Immunology 13, 2022 | 31 | 2022 |
Hypoxia increases mutational load of breast cancer cells through frameshift mutations G Hassan Venkatesh, P Bravo, W Shaaban Moustafa Elsayed, ... OncoImmunology 9 (1), 1750750, 2020 | 25 | 2020 |
Expression of eukaryotic initiation factor 4E and 4E binding protein 1 in colorectal carcinogenesis M Diab-Assaf, R Abou-Khouzam, N Saadallah-Zeidan, K Habib, N Bitar, ... International journal of clinical and experimental pathology 8 (1), 404, 2015 | 20 | 2015 |
E-cadherin Downregulation and microRNAs in sporadic intestinal-type gastric Cancer T Rossi, G Tedaldi, E Petracci, R Abou Khouzam, GN Ranzani, ... International journal of molecular sciences 20 (18), 4452, 2019 | 19 | 2019 |
Multigene Panel Testing Increases the Number of Loci Associated with Gastric Cancer Predisposition G Tedaldi, F Pirini, M Tebaldi, V Zampiga, I Cangini, R Danesi, ... Cancers 11 (9), 1340, 2019 | 18 | 2019 |
Tumor hypoxia: an important regulator of tumor progression or a potential modulator of tumor immunogenicity? G Hassan Venkatesh, R Abou Khouzam, W Shaaban Moustafa Elsayed, ... OncoImmunology 10 (1), 1974233, 2021 | 14 | 2021 |
Colorectal adenomatous polyposis: heterogeneity of susceptibility gene mutations and phenotypes in a cohort of italian patients M Marabelli, V Molinaro, RA Khouzam, E Berrino, M Panero, A Balsamo, ... Genetic testing and molecular biomarkers 20 (12), 777-785, 2016 | 12 | 2016 |
Colossolactone-G synergizes the anticancer properties of 5-fluorouracil and gemcitabine against colorectal cancer cells RA Algehani, R Abou Khouzam, GA Hegazy, AA Alamoudi, ... Biomedicine & Pharmacotherapy 140, 111730, 2021 | 11 | 2021 |
A novel APC promoter 1B deletion shows a founder effect in Italian patients with classical familial adenomatous polyposis phenotype M Marabelli, V Gismondi, MT Ricci, A Vetro, R Abou Khouzam, V Rea, ... Genes, Chromosomes and Cancer 56 (12), 846-854, 2017 | 11 | 2017 |
Hypoxia, a Targetable Culprit to Counter Pancreatic Cancer Resistance to Therapy R Abou Khouzam, JM Lehn, H Mayr, PA Clavien, MB Wallace, M Ducreux, ... Cancers 15 (4), 1235, 2023 | 9 | 2023 |
Waterpipe smoke condensate influences epithelial to mesenchymal transition and interferes with the cytotoxic immune response in non-small cell lung cancer cell lines RF Zaarour, P Prasad, GH Venkatesh, RA Khouzam, F Amirtharaj, ... Oncology reports 45 (3), 879-890, 2021 | 9 | 2021 |
Digital PCR identifies changes in CDH1 (E-cadherin) transcription pattern in intestinal-type gastric cancer R Abou Khouzam, C Molinari, S Salvi, M Marabelli, V Molinaro, D Orioli, ... Oncotarget 8 (12), 18811, 2017 | 9 | 2017 |
Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes S Harakeh, R Abou-Khouzam, GA Damanhouri, A Al-Hejin, T Kumosani, ... International Journal of Oncology 45 (5), 2159-2166, 2014 | 7 | 2014 |
Hypoxia as a potential inducer of immune tolerance, tumor plasticity and a driver of tumor mutational burden: Impact on cancer immunotherapy R Abou Khouzam, B Janji, J Thiery, RF Zaarour, AN Chamseddine, ... Seminars in Cancer Biology, 2023 | 4 | 2023 |
Genomic Analysis of Waterpipe Smoke-Induced Lung Tumor Autophagy and Plasticity RF Zaarour, M Sharda, B Azakir, G Hassan Venkatesh, R Abou Khouzam, ... International journal of molecular sciences 23 (12), 6848, 2022 | 3 | 2022 |
Chronic hypoxia is associated with transcriptomic reprogramming and increased genomic instability in cancer cells R Abou Khouzam, M Sharda, SP Rao, SM Kyerewah-Kersi, ... Frontiers in Cell and Developmental Biology 11, 2023 | 2 | 2023 |