Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris H Hohenblum, B Gasser, M Maurer, N Borth, D Mattanovich Biotechnology and bioengineering 85 (4), 367-375, 2004 | 382 | 2004 |
Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12, 1-7, 2016 | 317 | 2016 |
Process parameter shifting: Part I. Effect of DOT, pH, and temperature on the performance of Epo‐Fc expressing CHO cells cultivated in controlled batch bioreactors E Trummer, K Fauland, S Seidinger, K Schriebl, C Lattenmayer, R Kunert, ... Biotechnology and bioengineering 94 (6), 1033-1044, 2006 | 271 | 2006 |
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... Cell systems 3 (5), 434-443. e8, 2016 | 247 | 2016 |
Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line N Borth, D Mattanovich, R Kunert, H Katinger Biotechnology progress 21 (1), 106-111, 2005 | 242 | 2005 |
Applications of cell sorting in biotechnology D Mattanovich, N Borth Microbial cell factories 5, 1-11, 2006 | 204 | 2006 |
Chinese hamster genome sequenced from sorted chromosomes K Brinkrolf, O Rupp, H Laux, F Kollin, W Ernst, B Linke, R Kofler, ... Nature biotechnology 31 (8), 694-695, 2013 | 188 | 2013 |
Genetically different wine yeasts isolated from Austrian vine-growing regions influence wine aroma differently and contain putative hybrids between Saccharomyces cerevisiae and … K Lopandic, H Gangl, E Wallner, G Tscheik, G Leitner, A Querol, N Borth, ... FEMS Yeast Research 7 (6), 953-965, 2007 | 158 | 2007 |
Efficient selection of high‐producing subclones during gene amplification of recombinant Chinese hamster ovary cells by flow cytometry and cell sorting N Borth, M Zeyda, H Katinger Biotechnology and bioengineering 71 (4), 266-273, 2000 | 154 | 2000 |
Baculovirus surface display: construction and screening of a eukaryotic epitope library W Ernst, R Grabherr, D Wegner, N Borth, A Grassauer, H Katinger Nucleic Acids Research 26 (7), 1718-1723, 1998 | 152 | 1998 |
Intracellular pH Distribution in Saccharomyces cerevisiae Cell Populations, Analyzed by Flow Cytometry M Valli, M Sauer, P Branduardi, N Borth, D Porro, D Mattanovich Applied and environmental microbiology 71 (3), 1515-1521, 2005 | 150 | 2005 |
Nucleotide and nucleotide sugar analysis by liquid chromatography-electrospray ionization-mass spectrometry on surface-conditioned porous graphitic carbon M Pabst, J Grass, R Fischl, R Leonard, C Jin, G Hinterkorner, N Borth, ... Analytical chemistry 82 (23), 9782-9788, 2010 | 149 | 2010 |
Improvement of Lactic Acid Production in Saccharomyces cerevisiae by Cell Sorting for High Intracellular pH M Valli, M Sauer, P Branduardi, N Borth, D Porro, D Mattanovich Applied and environmental microbiology 72 (8), 5492-5499, 2006 | 148 | 2006 |
Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time J Feichtinger, I Hernández, C Fischer, M Hanscho, N Auer, M Hackl, ... Biotechnology and bioengineering 113 (10), 2241-2253, 2016 | 143 | 2016 |
Assessing viability and cell-associated product of recombinant protein producing Pichia pastoris with flow cytometry H Hohenblum, N Borth, D Mattanovich Journal of biotechnology 102 (3), 281-290, 2003 | 142 | 2003 |
Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering M Hackl, T Jakobi, J Blom, D Doppmeier, K Brinkrolf, R Szczepanowski, ... Journal of biotechnology 153 (1-2), 62-75, 2011 | 129 | 2011 |
Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing J Becker, M Hackl, O Rupp, T Jakobi, J Schneider, R Szczepanowski, ... Journal of biotechnology 156 (3), 227-235, 2011 | 128 | 2011 |
A reference genome of the Chinese hamster based on a hybrid assembly strategy O Rupp, ML MacDonald, S Li, H Dhiman, S Polson, S Griep, K Heffner, ... Biotechnology and bioengineering 115 (8), 2087-2100, 2018 | 114 | 2018 |
Dynamic mRNA and miRNA profiling of CHO‐K1 suspension cell cultures JAH Bort, M Hackl, H Höflmayer, V Jadhav, E Harreither, N Kumar, ... Biotechnology journal 7 (4), 500-515, 2012 | 112 | 2012 |
Process parameter shifting: Part II. Biphasic cultivation—A tool for enhancing the volumetric productivity of batch processes using Epo‐Fc expressing CHO cells E Trummer, K Fauland, S Seidinger, K Schriebl, C Lattenmayer, R Kunert, ... Biotechnology and bioengineering 94 (6), 1045-1052, 2006 | 110 | 2006 |