ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions PB Verghese, JM Castellano, K Garai, Y Wang, H Jiang, A Shah, G Bu, ... Proceedings of the National Academy of Sciences 110 (19), E1807-E1816, 2013 | 631 | 2013 |
Measuring size distribution in highly heterogeneous systems with fluorescence correlation spectroscopy P Sengupta, K Garai, J Balaji, N Periasamy, S Maiti Biophysical journal 84 (3), 1977-1984, 2003 | 249 | 2003 |
Unmasking the roles of N-and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation SL Crick, KM Ruff, K Garai, C Frieden, RV Pappu Proceedings of the National Academy of Sciences 110 (50), 20075-20080, 2013 | 231 | 2013 |
The amyloid β peptide (Aβ1-40) is thermodynamically soluble at physiological concentrations P Sengupta, K Garai, B Sahoo, Y Shi, DJE Callaway, S Maiti Biochemistry 42 (35), 10506-10513, 2003 | 198 | 2003 |
Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ K Garai, C Frieden Proceedings of the National Academy of Sciences 110 (9), 3321-3326, 2013 | 150 | 2013 |
Structural differences between apoE3 and apoE4 may be useful in developing therapeutic agents for Alzheimer’s disease C Frieden, K Garai Proceedings of the National Academy of Sciences 109 (23), 8913-8918, 2012 | 145 | 2012 |
Zinc lowers amyloid-β toxicity by selectively precipitating aggregation intermediates K Garai, B Sahoo, SK Kaushalya, R Desai, S Maiti Biochemistry 46 (37), 10655-10663, 2007 | 134 | 2007 |
The binding of apolipoprotein E to oligomers and fibrils of amyloid-β alters the kinetics of amyloid aggregation K Garai, PB Verghese, B Baban, DM Holtzman, C Frieden Biochemistry 53 (40), 6323-6331, 2014 | 133 | 2014 |
Selective destabilization of soluble amyloid β oligomers by divalent metal ions K Garai, P Sengupta, B Sahoo, S Maiti Biochemical and biophysical research communications 345 (1), 210-215, 2006 | 127 | 2006 |
Quantitative assessments of the distinct contributions of polypeptide backbone amides versus side chain groups to chain expansion via chemical denaturation AS Holehouse, K Garai, N Lyle, A Vitalis, RV Pappu Journal of the American Chemical Society 137 (8), 2984-2995, 2015 | 112 | 2015 |
Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization RYC Huang, K Garai, C Frieden, ML Gross Biochemistry 50 (43), 9273-9282, 2011 | 99 | 2011 |
Lipopolysaccharide from gut microbiota modulates α-synuclein aggregation and alters its biological function D Bhattacharyya, GM Mohite, J Krishnamoorthy, N Gayen, S Mehra, ... ACS chemical neuroscience 10 (5), 2229-2236, 2019 | 87 | 2019 |
Mass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4 B Gau, K Garai, C Frieden, ML Gross Biochemistry 50 (38), 8117-8126, 2011 | 74 | 2011 |
The association− dissociation behavior of the ApoE proteins: Kinetic and equilibrium studies K Garai, C Frieden Biochemistry 49 (44), 9533-9541, 2010 | 66 | 2010 |
Dissociation of apolipoprotein E oligomers to monomer is required for high-affinity binding to phospholipid vesicles K Garai, B Baban, C Frieden Biochemistry 50 (13), 2550-2558, 2011 | 62 | 2011 |
Quasihomogeneous nucleation of amyloid beta yields numerical bounds for the critical radius, the surface tension, and the free energy barrier for nucleus formation K Garai, B Sahoo, P Sengupta, S Maiti The Journal of Chemical Physics 128 (4), 2008 | 60 | 2008 |
Detecting amyloid-β aggregation with fiber-based fluorescence correlation spectroscopy K Garai, R Sureka, S Maiti Biophysical journal 92 (7), L55-L57, 2007 | 52 | 2007 |
Probing transient non-native states in amyloid beta fiber elongation by NMR JR Brender, A Ghosh, SA Kotler, J Krishnamoorthy, S Bera, V Morris, ... Chemical Communications 55 (31), 4483-4486, 2019 | 51 | 2019 |
Concerning the structure of apoE C Frieden, K Garai Protein Science 22 (12), 1820-1825, 2013 | 48 | 2013 |
Expression and purification of amyloid-β peptides from Escherichia coli K Garai, SL Crick, SM Mustafi, C Frieden Protein expression and purification 66 (1), 107-112, 2009 | 47 | 2009 |