A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation L Braun, MP Brenier-Pinchart, M Yogavel, A Curt-Varesano, ... Journal of Experimental Medicine 210 (10), 2071-2086, 2013 | 286 | 2013 |
Structure of prolyl-tRNA synthetase-halofuginone complex provides basis for development of drugs against malaria and toxoplasmosis V Jain, M Yogavel, Y Oshima, H Kikuchi, B Touquet, MA Hakimi, ... Structure 23 (5), 819-829, 2015 | 108 | 2015 |
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis B Baragaña, B Forte, R Choi, S Nakazawa Hewitt, JA Bueren-Calabuig, ... Proceedings of the National Academy of Sciences 116 (14), 7015-7020, 2019 | 107 | 2019 |
Characterization of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) and its role in microneme secretion during erythrocyte invasion A Bansal, S Singh, KR More, D Hans, K Nangalia, M Yogavel, A Sharma, ... Journal of Biological Chemistry 288 (3), 1590-1602, 2013 | 104 | 2013 |
Structural analysis of ABC-family periplasmic zinc binding protein provides new insights into mechanism of ligand uptake and release BR Chandra, M Yogavel, A Sharma Journal of molecular biology 367 (4), 970-982, 2007 | 98 | 2007 |
Targeting prolyl-tRNA synthetase to accelerate drug discovery against malaria, leishmaniasis, toxoplasmosis, cryptosporidiosis, and coccidiosis V Jain, M Yogavel, H Kikuchi, Y Oshima, N Hariguchi, M Matsumoto, ... Structure 25 (10), 1495-1505. e6, 2017 | 76 | 2017 |
Malaria parasite tyrosyl-tRNA synthetase secretion triggers pro-inflammatory responses TK Bhatt, S Khan, VP Dwivedi, MM Banday, A Sharma, A Chandele, ... Nature communications 2 (1), 530, 2011 | 72 | 2011 |
Structural basis of malaria parasite lysyl-tRNA synthetase inhibition by cladosporin S Khan, A Sharma, H Belrhali, M Yogavel, A Sharma Journal of structural and functional genomics 15, 63-71, 2014 | 68 | 2014 |
Drug targeting of one or more aminoacyl-tRNA synthetase in the malaria parasite Plasmodium falciparum Y Manickam, R Chaturvedi, P Babbar, N Malhotra, V Jain, A Sharma Drug discovery today 23 (6), 1233-1240, 2018 | 51 | 2018 |
Inhibition of protein synthesis and malaria parasite development by drug targeting of methionyl-tRNA synthetases T Hussain, M Yogavel, A Sharma Antimicrobial agents and chemotherapy 59 (4), 1856-1867, 2015 | 48 | 2015 |
Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetase V Jain, H Kikuchi, Y Oshima, A Sharma, M Yogavel Journal of structural and functional genomics 15, 181-190, 2014 | 47 | 2014 |
Specific stereoisomeric conformations determine the drug potency of cladosporin scaffold against malarial parasite P Das, P Babbar, N Malhotra, M Sharma, GR Jachak, RG Gonnade, ... Journal of Medicinal Chemistry 61 (13), 5664-5678, 2018 | 46 | 2018 |
Crystal structure of malaria parasite nucleosome assembly protein J Gill, M Yogavel, A Kumar, H Belrhali, SK Jain, M Rug, M Brown, ... Journal of biological chemistry 284 (15), 10076-10087, 2009 | 45 | 2009 |
Crystal structure of soluble domain of malaria sporozoite protein UIS3 in complex with lipid A Sharma, M Yogavel, RR Akhouri, J Gill, A Sharma Journal of biological chemistry 283 (35), 24077-24088, 2008 | 42 | 2008 |
Ligand-bound structures provide atomic snapshots for the catalytic mechanism of D-amino acid deacylase TK Bhatt, M Yogavel, S Wydau, R Berwal, A Sharma Journal of biological chemistry 285 (8), 5917-5930, 2010 | 37 | 2010 |
Structure of a superoxide dismutase and implications for copper-ion chelation M Yogavel, PC Mishra, J Gill, PK Bhardwaj, S Dutt, S Kumar, PS Ahuja, ... Acta Crystallographica Section D: Biological Crystallography 64 (8), 892-901, 2008 | 36 | 2008 |
Structure, localization and histone binding properties of nuclear-associated nucleosome assembly protein from Plasmodium falciparum J Gill, A Kumar, M Yogavel, H Belrhali, SK Jain, M Rug, M Brown, ... Malaria journal 9, 1-15, 2010 | 32 | 2010 |
SAD phasing of a structure based on cocrystallized iodides using an in-house Cu Kα X-ray source: effects of data redundancy and completeness on structure solution M Yogavel, J Gill, PC Mishra, A Sharma Acta Crystallographica Section D: Biological Crystallography 63 (8), 931-934, 2007 | 31 | 2007 |
Crystal structures of the free and anisic acid bound triple mutant of phospholipase A2 K Sekar, SV Mala, M Yogavel, D Velmurugan, MJ Poi, BS Vishwanath, ... Journal of molecular biology 333 (2), 367-376, 2003 | 31 | 2003 |
Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines M Sharma, N Malhotra, M Yogavel, K Harlos, B Melillo, E Comer, A Gonse, ... Nature communications 12 (1), 343, 2021 | 26 | 2021 |