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Xavier Saelens
Xavier Saelens
在 vib-ugent.be 的电子邮件经过验证 - 首页
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Toxic proteins released from mitochondria in cell death
X Saelens, N Festjens, LV Walle, M Gurp, G Loo, P Vandenabeele
Oncogene 23 (16), 2861-2874, 2004
14822004
A universal influenza A vaccine based on the extracellular domain of the M2 protein
S Neirynck, T Deroo, X Saelens, P Vanlandschoot, WM Jou, W Fiers
Nature medicine 5 (10), 1157-1163, 1999
10391999
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet
G van Loo, X Saelens, M Van Gurp, M MacFarlane, SJ Martin, ...
Cell Death & Differentiation 9 (10), 1031-1042, 2002
8702002
Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies
D Wrapp, D De Vlieger, KS Corbett, GM Torres, N Wang, W Van Breedam, ...
Cell 181 (5), 1004-1015. e15, 2020
6432020
Mitochondrial intermembrane proteins in cell death
M Van Gurp, N Festjens, G Van Loo, X Saelens, P Vandenabeele
Biochemical and biophysical research communications 304 (3), 487-497, 2003
5442003
Alice in caspase land. A phylogenetic analysis of caspases from worm to man
M Lamkanfi, W Declercq, M Kalai, X Saelens, P Vandenabeele
Cell death and differentiation 9 (4), 358-361, 2002
5292002
Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection
K El Bakkouri, F Descamps, M De Filette, A Smet, E Festjens, A Birkett, ...
The Journal of Immunology 186 (2), 1022-1031, 2011
3822011
Mx proteins: antiviral gatekeepers that restrain the uninvited
J Verhelst, P Hulpiau, X Saelens
Microbiology and Molecular Biology Reviews 77 (4), 551-566, 2013
3562013
Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments
M Schotsaert, M De Filette, W Fiers, X Saelens
Expert review of vaccines 8 (4), 499-508, 2009
3032009
M2e-based universal influenza A vaccine
W Fiers, M De Filette, K El Bakkouri, B Schepens, K Roose, M Schotsaert, ...
Vaccine 27 (45), 6280-6283, 2009
2992009
Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production
G Brouckaert, M Kalai, DV Krysko, X Saelens, D Vercammen, M Ndlovu, ...
Molecular biology of the cell 15 (3), 1089-1100, 2004
2932004
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters
R Boudewijns, HJ Thibaut, SJF Kaptein, R Li, V Vergote, L Seldeslachts, ...
Nature communications 11 (1), 5838, 2020
2772020
Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly
J Verhelst, E Parthoens, B Schepens, W Fiers, X Saelens
Journal of virology 86 (24), 13445-13455, 2012
2622012
Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-α phosphorylation
X Saelens, M Kalai, P Vandenabeele
Journal of Biological Chemistry 276 (45), 41620-41628, 2001
2262001
Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules
A Hultberg, NJ Temperton, V Rosseels, M Koenders, M Gonzalez-Pajuelo, ...
PloS one 6 (4), e17665, 2011
2152011
Improved design and intranasal delivery of an M2e-based human influenza A vaccine
M De Filette, W Fiers, W Martens, A Birkett, A Ramne, B Löwenadler, ...
Vaccine 24 (44-46), 6597-6601, 2006
1972006
M2e-based universal influenza A vaccines
L Deng, KJ Cho, W Fiers, X Saelens
Vaccines 3 (1), 105-136, 2015
1922015
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
M Kalai, G Van Loo, T Vanden Berghe, A Meeus, W Burm, X Saelens, ...
Cell Death & Differentiation 9 (9), 981-994, 2002
1912002
An influenza A vaccine based on tetrameric ectodomain of matrix protein 2
M De Filette, W Martens, K Roose, T Deroo, F Vervalle, M Bentahir, ...
Journal of Biological Chemistry 283 (17), 11382-11387, 2008
1882008
Caspase-1 activates nuclear factor of the κ-enhancer in B cells independently of its enzymatic activity
M Lamkanfi, M Kalai, X Saelens, W Declercq, P Vandenabeele
Journal of Biological Chemistry 279 (23), 24785-24793, 2004
1782004
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