Toxic proteins released from mitochondria in cell death X Saelens, N Festjens, LV Walle, M Gurp, G Loo, P Vandenabeele Oncogene 23 (16), 2861-2874, 2004 | 1482 | 2004 |
A universal influenza A vaccine based on the extracellular domain of the M2 protein S Neirynck, T Deroo, X Saelens, P Vanlandschoot, WM Jou, W Fiers Nature medicine 5 (10), 1157-1163, 1999 | 1039 | 1999 |
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet G van Loo, X Saelens, M Van Gurp, M MacFarlane, SJ Martin, ... Cell Death & Differentiation 9 (10), 1031-1042, 2002 | 870 | 2002 |
Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies D Wrapp, D De Vlieger, KS Corbett, GM Torres, N Wang, W Van Breedam, ... Cell 181 (5), 1004-1015. e15, 2020 | 643 | 2020 |
Mitochondrial intermembrane proteins in cell death M Van Gurp, N Festjens, G Van Loo, X Saelens, P Vandenabeele Biochemical and biophysical research communications 304 (3), 487-497, 2003 | 544 | 2003 |
Alice in caspase land. A phylogenetic analysis of caspases from worm to man M Lamkanfi, W Declercq, M Kalai, X Saelens, P Vandenabeele Cell death and differentiation 9 (4), 358-361, 2002 | 529 | 2002 |
Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection K El Bakkouri, F Descamps, M De Filette, A Smet, E Festjens, A Birkett, ... The Journal of Immunology 186 (2), 1022-1031, 2011 | 382 | 2011 |
Mx proteins: antiviral gatekeepers that restrain the uninvited J Verhelst, P Hulpiau, X Saelens Microbiology and Molecular Biology Reviews 77 (4), 551-566, 2013 | 356 | 2013 |
Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments M Schotsaert, M De Filette, W Fiers, X Saelens Expert review of vaccines 8 (4), 499-508, 2009 | 303 | 2009 |
M2e-based universal influenza A vaccine W Fiers, M De Filette, K El Bakkouri, B Schepens, K Roose, M Schotsaert, ... Vaccine 27 (45), 6280-6283, 2009 | 299 | 2009 |
Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production G Brouckaert, M Kalai, DV Krysko, X Saelens, D Vercammen, M Ndlovu, ... Molecular biology of the cell 15 (3), 1089-1100, 2004 | 293 | 2004 |
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters R Boudewijns, HJ Thibaut, SJF Kaptein, R Li, V Vergote, L Seldeslachts, ... Nature communications 11 (1), 5838, 2020 | 277 | 2020 |
Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly J Verhelst, E Parthoens, B Schepens, W Fiers, X Saelens Journal of virology 86 (24), 13445-13455, 2012 | 262 | 2012 |
Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-α phosphorylation X Saelens, M Kalai, P Vandenabeele Journal of Biological Chemistry 276 (45), 41620-41628, 2001 | 226 | 2001 |
Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules A Hultberg, NJ Temperton, V Rosseels, M Koenders, M Gonzalez-Pajuelo, ... PloS one 6 (4), e17665, 2011 | 215 | 2011 |
Improved design and intranasal delivery of an M2e-based human influenza A vaccine M De Filette, W Fiers, W Martens, A Birkett, A Ramne, B Löwenadler, ... Vaccine 24 (44-46), 6597-6601, 2006 | 197 | 2006 |
M2e-based universal influenza A vaccines L Deng, KJ Cho, W Fiers, X Saelens Vaccines 3 (1), 105-136, 2015 | 192 | 2015 |
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA M Kalai, G Van Loo, T Vanden Berghe, A Meeus, W Burm, X Saelens, ... Cell Death & Differentiation 9 (9), 981-994, 2002 | 191 | 2002 |
An influenza A vaccine based on tetrameric ectodomain of matrix protein 2 M De Filette, W Martens, K Roose, T Deroo, F Vervalle, M Bentahir, ... Journal of Biological Chemistry 283 (17), 11382-11387, 2008 | 188 | 2008 |
Caspase-1 activates nuclear factor of the κ-enhancer in B cells independently of its enzymatic activity M Lamkanfi, M Kalai, X Saelens, W Declercq, P Vandenabeele Journal of Biological Chemistry 279 (23), 24785-24793, 2004 | 178 | 2004 |