Discovery of benzo [cd] indol-2-one and benzylidene-thiazolidine-2, 4-dione as new classes of NLRP3 inflammasome inhibitors via ER-β structure based virtual screening M Abdullaha, M Ali, D Kour, A Kumar, SB Bharate Bioorganic chemistry 95, 103500, 2020 | 19 | 2020 |
Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP A Dogra, D Kour, A Gour, M Bhardwaj, S Bag, SK Dhiman, A Kumar, ... Drug and Chemical Toxicology 46 (3), 597-608, 2023 | 10 | 2023 |
Tetramethoxystilbene inhibits NLRP3 inflammasome assembly via blocking the oligomerization of apoptosis-associated speck-like protein containing caspase recruitment domain: in … M Abdullaha, M Ali, D Kour, R Mudududdla, P Khajuria, A Kumar, ... ACS Pharmacology & Translational Science 4 (4), 1437-1448, 2021 | 10 | 2021 |
Effect of Concomitant Hydroxyurea Therapy with Rutin and Gallic Acid: Integration of Pharmacokinetic and Pharmacodynamic Approaches A Gour, A Dogra, D Kour, G Singh, A Kumar, U Nandi ACS omega 6 (22), 14542-14550, 2021 | 9 | 2021 |
Glabridin plays dual action to augment the efficacy and attenuate the hepatotoxicity of methotrexate in arthritic rats A Dogra, D Kour, M Bhardwaj, S Dhiman, A Kumar, B Vij, A Kumar, ... ACS omega 7 (38), 34341-34351, 2022 | 8 | 2022 |
IIIM-941, a stilbene derivative inhibits NLRP3 inflammasome activation by inducing autophagy M Ali, M Gupta, A Wani, A Sharma, M Abdullaha, D Kour, S Choudhary, ... Frontiers in Pharmacology 12, 695712, 2021 | 8 | 2021 |
Molecular mechanism for the involvement of CYP2E1/NF-κB axis in bedaquiline-induced hepatotoxicity P Kotwal, P Khajuria, S Dhiman, D Kour, SK Dhiman, A Kumar, U Nandi Life Sciences 315, 121375, 2023 | 7 | 2023 |
Epicatechin exerts dual action to shield sickling and hydroxyurea-induced myelosuppression: Implication in sickle cell anemia management A Gour, D Kour, A Dogra, D Manhas, P Wazir, SK Digra, A Kumar, ... Toxicology and Applied Pharmacology 449, 116113, 2022 | 5 | 2022 |
Investigating the Potential Use of Andrographolide as a Coadjuvant in Sickle Cell Anemia Therapy A Gour, P Kotwal, A Dogra, D Kour, S Dhiman, A Kumar, SK Digra, ... ACS omega 7 (15), 12765-12771, 2022 | 3 | 2022 |
Site-selective synthesis and pharmacological elucidation of novel semi-synthetic analogues of koenimbine as a potential anti-inflammatory agent NI Andrabi, AR Sarkar, SA Haq, D Kour, D Saroch, SK Shukla, A Kumar, ... International Immunopharmacology 126, 111059, 2024 | 2 | 2024 |
Ayurveda-based phytochemical composition attenuates lung inflammation and precipitates pharmacokinetic interaction with favipiravir: an in vivo investigation … A Gour, A Dogra, MK Verma, M Bhardwaj, D Kour, A Jamwal, B Gorain, ... Natural Product Research 37 (22), 3758-3765, 2023 | 2 | 2023 |
In-vitro anti-sickling potential of baicalin and naringenin isolated from Oroxylum indicum and Citrus aurantium on human sickle red blood cells BA Lone, N Sharma, D Kour, A Bhushan, D Rani, A Kumar, PK Gupta, ... Natural Product Research 37 (22), 3902-3908, 2023 | 2 | 2023 |
Assessment of threatened status, phytochemical composition and biological properties of three Aconitum species from Kashmir Himalaya-India. Curr Bot 12: 85–96 S Ali, D Kour, A Ntemafack, N Kapoor, P Sultan, A Kumar, SG Gandhi, ... | 2 | 2021 |
ADME/PK Insights of Crocetin: A Molecule Having an Unusual Chemical Structure with Druglike Features D Manhas, S Dhiman, H Kour, D Kour, K Sharma, P Wazir, B Vij, A Kumar, ... ACS omega 9 (19), 21494-21509, 2024 | 1 | 2024 |
Ellagic Acid Exerts Dual Action to Curb the Pathophysiological Manifestations of Sickle Cell Disease and Attenuate the Hydroxyurea-Induced Myelosuppression in Berkeley Mice A Gour, D Kour, R Pandian, M Bhardwaj, SD Sawant, A Kumar, U Nandi ACS Pharmacology & Translational Science 6 (6), 868-877, 2023 | 1 | 2023 |
Flurbiprofen inhibits heme induced NLRP3 inflammasome in Berkeley sickle cell disease mice D Kour, M Ali, P Khajuria, K Sharma, P Ghosh, S Kaur, S Mahajan, ... Frontiers in Pharmacology 14, 1123734, 2023 | 1 | 2023 |
Gentiacaulein inhibits glucose transport to induce PRKAA1-mediated autophagy to clear amyloid beta and associated inflammation in primary astrocytes A Sharma, S Kaur, A Wani, D Kour, M Ali, SM Ali, L Singh, A Gour, ... Autophagy Reports 3 (1), 2296209, 2024 | | 2024 |
EIDD-1931 Treatment Tweaks CYP3A4 and CYP2C8 in Arthritic Rats to Expedite Drug Interaction: Implication in Oral Therapy of Molnupiravir M Bhardwaj, D Kour, G Rai, S Bhattacharya, D Manhas, B Vij, A Kumar, ... ACS omega 9 (12), 13982-13993, 2024 | | 2024 |
Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in 5XFAD mice D Kour, P Khajuria, K Sharma, A Sharma, A Sharma, SM Ali, P Wazir, ... | | 2023 |