| Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients LG Radvanyi, C Bernatchez, M Zhang, PS Fox, P Miller, J Chacon, R Wu, ... Clinical Cancer Research 18 (24), 6758-6770, 2012 | 462 | 2012 |
| Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook R Wu, MA Forget, J Chacon, C Bernatchez, C Haymaker, JQ Chen, P Hwu, ... The Cancer Journal 18 (2), 160-175, 2012 | 330 | 2012 |
| Co-Stimulation through 4-1BB/CD137 Improves the Expansion and Function of CD8+ Melanoma Tumor-Infiltrating Lymphocytes for Adoptive T-Cell Therapy JA Chacon, RC Wu, P Sukhumalchandra, JJ Molldrem, A Sarnaik, ... PloS one 8 (4), e60031, 2013 | 164 | 2013 |
| Costimulation through the CD137/4-1BB pathway protects human melanoma tumor-infiltrating lymphocytes from activation-induced cell death and enhances antitumor effector function JA Hernandez-Chacon, Y Li, RC Wu, C Bernatchez, Y Wang, JS Weber, ... Journal of immunotherapy 34 (3), 236-250, 2011 | 162 | 2011 |
| Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced by surface antigen expression level DG Song, Q Ye, M Poussin, JA Chacon, M Figini, DJ Powell Journal of hematology & oncology 9, 1-12, 2016 | 151 | 2016 |
| MART-1–specific melanoma tumor-infiltrating lymphocytes maintaining CD28 expression have improved survival and expansion capability following antigenic restimulation in vitro Y Li, S Liu, J Hernandez, L Vence, P Hwu, L Radvanyi The journal of immunology 184 (1), 452-465, 2010 | 129 | 2010 |
| Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy AA Sarnaik, JS Weber, S Pilon-Thomas, LG Radvanyi, JA Chacon, ... US Patent App. 15/303,201, 2017 | 91 | 2017 |
| Manipulating the Tumor Microenvironment Ex Vivo for Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy JA Chacon, AA Sarnaik, JQ Chen, C Creasy, C Kale, J Robinson, J Weber, ... Clinical Cancer Research 21 (3), 611-621, 2015 | 68 | 2015 |
| 4-1BB–Enhanced Expansion of CD8+ TIL from Triple-Negative Breast Cancer Unveils Mutation-Specific CD8+ T Cells M Harao, MA Forget, J Roszik, H Gao, GV Babiera, S Krishnamurthy, ... Cancer immunology research 5 (6), 439-445, 2017 | 62 | 2017 |
| Implications of enhancer transcription and eRNAs in cancer S Adhikary, S Roy, J Chacon, SS Gadad, C Das Cancer Research 81 (16), 4174-4182, 2021 | 48 | 2021 |
| The impact of chemotherapy, radiation and epigenetic modifiers in cancer cell expression of immune inhibitory and stimulatory molecules and anti-tumor efficacy JA Chacon, K Schutsky, DJ Powell Jr Vaccines 4 (4), 43, 2016 | 42 | 2016 |
| Tumor-infiltrating lymphocyte therapy for melanoma: rationale and issues for further clinical development GC Sim, J Chacon, C Haymaker, K Ritthipichai, M Singh, P Hwu, ... BioDrugs 28, 421-437, 2014 | 36 | 2014 |
| Systematic analysis of CD39, CD103, CD137, and PD‐1 as biomarkers for naturally occurring tumor antigen‐specific TILs MA Eiva, DK Omran, JA Chacon, DJ Powell Jr European journal of immunology 52 (1), 96-108, 2022 | 33 | 2022 |
| Peptide drug conjugates and their role in cancer therapy E Heh, J Allen, F Ramirez, D Lovasz, L Fernandez, T Hogg, H Riva, ... International Journal of Molecular Sciences 24 (1), 829, 2023 | 32 | 2023 |
| Continuous 4–1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy JA Chacon, S Pilon-Thomas, AA Sarnaik, LG Radvanyi Oncoimmunology 2 (9), e25581, 2013 | 28 | 2013 |
| Detection and Characterization of a Novel Subset of CD8+CD57+ T Cells in Metastatic Melanoma with an Incompletely Differentiated Phenotype RC Wu, S Liu, JA Chacon, S Wu, Y Li, P Sukhumalchandra, JL Murray, ... Clinical Cancer Research 18 (9), 2465-2477, 2012 | 24 | 2012 |
| Teaching critical thinking and problem-solving skills to healthcare professionals JA Chacon, H Janssen Medical Science Educator 31 (1), 235-239, 2021 | 19 | 2021 |
| Harnessing the immune system with cancer vaccines: From prevention to therapeutics I Le, S Dhandayuthapani, J Chacon, AM Eiring, SS Gadad Vaccines 10 (5), 816, 2022 | 13 | 2022 |
| Triggering co-stimulation directly in melanoma tumor fragments drives CD8+ tumor-infiltrating lymphocyte expansion with improved effector-memory properties JA Chacon, AA Sarnaik, S Pilon-Thomas, L Radvanyi Oncoimmunology 4 (12), e1040219, 2015 | 12 | 2015 |
| Lovastatin inhibits T-cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs D Li, Y Li, JA Hernandez, R Patenia, TK Kim, J Khalili, MC Dougherty, ... Journal of Immunotherapy 33 (9), 975-982, 2010 | 12 | 2010 |
