关注
Aisling Anna Roche
Aisling Anna Roche
GSK Biopharm Discovery
在 gsk.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Advancing therapeutic protein discovery and development through comprehensive computational and biophysical characterization
L Gentiluomo, HL Svilenov, D Augustijn, I El Bialy, ML Greco, A Kulakova, ...
Molecular Pharmaceutics 17 (2), 426-440, 2019
452019
Determination of protein–protein interactions in a mixture of two monoclonal antibodies
P Singh, A Roche, CF Van der Walle, S Uddin, J Du, J Warwicker, A Pluen, ...
Molecular Pharmaceutics 16 (12), 4775-4786, 2019
272019
Models for antibody behavior in hydrophobic interaction chromatography and in self-association
M Hebditch, A Roche, RA Curtis, J Warwicker
Journal of pharmaceutical sciences 108 (4), 1434-1441, 2019
232019
Towards an improved prediction of concentrated antibody solution viscosity using the Huggins coefficient
A Roche, L Gentiluomo, N Sibanda, D Roessner, W Friess, SP Trainoff, ...
Journal of Colloid and Interface Science 607, 1813-1824, 2022
192022
Determination of Protein-protein interactions at high co-solvent concentrations using static and dynamic light scattering
L Holloway, A Roche, S Marzouk, S Uddin, P Ke, S Ekizoglou, R Curtis
Journal of Pharmaceutical Sciences 109 (9), 2699-2709, 2020
182020
Cluster Percolation Causes Shear Thinning Behavior in Concentrated Solutions of Monoclonal Antibodies
A Lanzaro, A Roche, N Sibanda, D Corbett, P Davis, M Shah, JA Pathak, ...
Molecular Pharmaceutics 18 (7), 2669-2682, 2021
122021
Micro-and macro-viscosity relations in high concentration antibody solutions
M Shah, D Corbett, A Lanzaro, A Roche, N Sibanda, P Davis, S Uddin, ...
European Journal of Pharmaceutics and Biopharmaceutics 153, 211-221, 2020
122020
Intermolecular Interactions and Rheological Properties in Monoclonal Antibody Solutions
A Roche
PQDT-Global, 2020
22020
Reconciling predicted and measured viscosity parameters in high concentration antibody solutions
GB Armstrong, A Roche, W Lewis, Z Rattray
2024
Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding
A Kulakova, D Augustijn, I El Bialy, L Gentiluomo, ML Greco, ...
Molecular Pharmaceutics 20 (6), 2951-2965, 2023
2023
The development of therapeutic proteins can be hindered by poor decision-making strategies in the early stage
L Gentiluomo, H Svilenov, M Morales, A Kulakova, IE Bialy, S Mahapatra, ...
2019
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