Advancing therapeutic protein discovery and development through comprehensive computational and biophysical characterization L Gentiluomo, HL Svilenov, D Augustijn, I El Bialy, ML Greco, A Kulakova, ... Molecular Pharmaceutics 17 (2), 426-440, 2019 | 45 | 2019 |
Determination of protein–protein interactions in a mixture of two monoclonal antibodies P Singh, A Roche, CF Van der Walle, S Uddin, J Du, J Warwicker, A Pluen, ... Molecular Pharmaceutics 16 (12), 4775-4786, 2019 | 27 | 2019 |
Models for antibody behavior in hydrophobic interaction chromatography and in self-association M Hebditch, A Roche, RA Curtis, J Warwicker Journal of pharmaceutical sciences 108 (4), 1434-1441, 2019 | 23 | 2019 |
Towards an improved prediction of concentrated antibody solution viscosity using the Huggins coefficient A Roche, L Gentiluomo, N Sibanda, D Roessner, W Friess, SP Trainoff, ... Journal of Colloid and Interface Science 607, 1813-1824, 2022 | 19 | 2022 |
Determination of Protein-protein interactions at high co-solvent concentrations using static and dynamic light scattering L Holloway, A Roche, S Marzouk, S Uddin, P Ke, S Ekizoglou, R Curtis Journal of Pharmaceutical Sciences 109 (9), 2699-2709, 2020 | 18 | 2020 |
Cluster Percolation Causes Shear Thinning Behavior in Concentrated Solutions of Monoclonal Antibodies A Lanzaro, A Roche, N Sibanda, D Corbett, P Davis, M Shah, JA Pathak, ... Molecular Pharmaceutics 18 (7), 2669-2682, 2021 | 12 | 2021 |
Micro-and macro-viscosity relations in high concentration antibody solutions M Shah, D Corbett, A Lanzaro, A Roche, N Sibanda, P Davis, S Uddin, ... European Journal of Pharmaceutics and Biopharmaceutics 153, 211-221, 2020 | 12 | 2020 |
Intermolecular Interactions and Rheological Properties in Monoclonal Antibody Solutions A Roche PQDT-Global, 2020 | 2 | 2020 |
Reconciling predicted and measured viscosity parameters in high concentration antibody solutions GB Armstrong, A Roche, W Lewis, Z Rattray | | 2024 |
Chemometrics in Protein Formulation: Stability Governed by Repulsion and Protein Unfolding A Kulakova, D Augustijn, I El Bialy, L Gentiluomo, ML Greco, ... Molecular Pharmaceutics 20 (6), 2951-2965, 2023 | | 2023 |
The development of therapeutic proteins can be hindered by poor decision-making strategies in the early stage L Gentiluomo, H Svilenov, M Morales, A Kulakova, IE Bialy, S Mahapatra, ... | | 2019 |