MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer F Meng, R Henson, H Wehbe–Janek, K Ghoshal, ST Jacob, T Patel Gastroenterology 133 (2), 647-658, 2007 | 3514 | 2007 |
MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1*♦ TE Miller, K Ghoshal, B Ramaswamy, S Roy, J Datta, CL Shapiro, S Jacob, ... Journal of biological chemistry 283 (44), 29897-29903, 2008 | 937 | 2008 |
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver S Hsu, B Wang, J Kota, J Yu, S Costinean, H Kutay, L Yu, S Bai, ... The Journal of clinical investigation 122 (8), 2871-2883, 2012 | 836 | 2012 |
Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas H Kutay, S Bai, J Datta, T Motiwala, I Pogribny, W Frankel, ST Jacob, ... Journal of cellular biochemistry 99 (3), 671-678, 2006 | 801 | 2006 |
MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib S Bai, MW Nasser, B Wang, SH Hsu, J Datta, H Kutay, A Yadav, G Nuovo, ... Journal of Biological Chemistry 284 (46), 32015-32027, 2009 | 637 | 2009 |
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues. BDP Eichhorn SW, Guo H, McGeary SE, Rodriguez-Mias RA, Shin C, Baek D, Hsu ... Molecular Cell 56 (1), 104-115, 2014 | 604 | 2014 |
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues. BDP Eichhorn SW, Guo H, McGeary SE, Rodriguez-Mias RA, Shin C, Baek D, Hsu ... Molecular Cell 56 (1), 104-115, 2014 | 604 | 2014 |
RETRACTED: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis J Datta, H Kutay, MW Nasser, GJ Nuovo, B Wang, S Majumder, CG Liu, ... Cancer research 68 (13), 5049-5058, 2008 | 571 | 2008 |
5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear … K Ghoshal, J Datta, S Majumder, S Bai, H Kutay, T Motiwala, ST Jacob Molecular and cellular biology, 2005 | 531 | 2005 |
TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3 B Wang, SH Hsu, S Majumder, H Kutay, W Huang, ST Jacob, K Ghoshal Oncogene 29 (12), 1787-1797, 2010 | 479 | 2010 |
CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma J Chu, Y Deng, DM Benson, S He, T Hughes, J Zhang, Y Peng, H Mao, ... Leukemia 28 (4), 917-927, 2014 | 470 | 2014 |
Down-regulation of micro-RNA-1 (miR-1) in lung cancer: suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1 MW Nasser, J Datta, G Nuovo, H Kutay, T Motiwala, S Majumder, B Wang, ... Journal of biological chemistry 283 (48), 33394-33406, 2008 | 462 | 2008 |
Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice B Wang, S Majumder, G Nuovo, H Kutay, S Volinia, T Patel, ... Hepatology 50 (4), 1152-1161, 2009 | 372 | 2009 |
A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation J Datta, K Ghoshal, WA Denny, SA Gamage, DG Brooke, P Phiasivongsa, ... Cancer research 69 (10), 4277, 2009 | 306 | 2009 |
Stat3‐mediated activation of microRNA‐23a suppresses gluconeogenesis in hepatocellular carcinoma by down‐regulating glucose‐6‐phosphatase and peroxisome proliferator‐activated … B Wang, SH Hsu, W Frankel, K Ghoshal, ST Jacob Hepatology 56 (1), 186-197, 2012 | 250 | 2012 |
miR-122 is a unique molecule with great potential in diagnosis, prognosis of liver disease, and therapy both as miRNA mimic and antimir S Thakral, K Ghoshal Current gene therapy 15 (2), 142-150, 2015 | 244 | 2015 |
A folate-and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats K Ghoshal, X Li, J Datta, S Bai, I Pogribny, M Pogribny, Y Huang, D Young, ... The Journal of nutrition 136 (6), 1522-1527, 2006 | 242 | 2006 |
Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression K Ghoshal, S Majumder, J Datta, T Motiwala, S Bai, SM Sharma, ... Journal of Biological Chemistry 279 (8), 6783-6793, 2004 | 230 | 2004 |
An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug K Ghoshal, ST Jacob Biochemical pharmacology 53 (11), 1569-1575, 1997 | 202 | 1997 |
DNA methyltransferases as targets for cancer therapy. K Ghoshal, S Bai Drugs of Today (Barcelona, Spain: 1998) 43 (6), 395-422, 2007 | 193 | 2007 |