Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins GGM Habets, EHM Scholtes, D Zuydgeest, RA van der Kammen, JC Stam, ... Cell 77 (4), 537-549, 1994 | 723 | 1994 |
A role for Rac in Tiaml-induced membrane ruffling and invasion F Michiels, GGM Habets, JC Stam, RA van der Kammen, JG Collard Nature 375 (6529), 338-340, 1995 | 701 | 1995 |
Glycosylation profiling of immunoglobulin G (IgG) subclasses from human serum M Wuhrer, JC Stam, FE van de Geijn, CAM Koeleman, CT Verrips, ... Proteomics 7 (22), 4070-4081, 2007 | 333 | 2007 |
Tissue factor: an enzyme cofactor and a true receptor JH Morrissey Thrombosis and haemostasis 86 (07), 66-74, 2001 | 310 | 2001 |
Regulated Membrane Localization of Tiam1, Mediated by the NH2-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH … F Michiels, JC Stam, PL Hordijk, RA Kammen, LRV Stalle, CA Feltkamp, ... The Journal of cell biology 137 (2), 387-398, 1997 | 284 | 1997 |
Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling JC Stam, F Michiels, RA Van der Kammen, WH Moolenaar, JG Collard The EMBO Journal 17 (14), 4066-4074, 1998 | 281 | 1998 |
Rapid visualization of human tumor xenografts through optical imaging with a near-infrared fluorescent anti–epidermal growth factor receptor nanobody S Oliveira, GAMS Van Dongen, MS Walsum, RC Roovers, JC Stam, ... Molecular imaging 11 (1), 7290.2011. 00025, 2012 | 220 | 2012 |
Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain JC Stam, EE Sander, F Michiels, FN van Leeuwen, HET Kain, ... Journal of Biological Chemistry 272 (45), 28447-28454, 1997 | 177 | 1997 |
Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac HH Versteeg, I Hoedemaeker, SH Diks, JC Stam, M Spaargaren, ... Journal of Biological Chemistry 275 (37), 28750-28756, 2000 | 143 | 2000 |
Sequence of the human invasion-inducing TIAM1 gene, its conservation in evolution and its expression in tumor cell lines of different tissue origin. GG Habets, RA Van der Kammen, JC Stam, F Michiels, JG Collard Oncogene 10 (7), 1371-1376, 1995 | 136 | 1995 |
Improved anti-IgG and HSA affinity ligands: clinical application of VHH antibody technology R Klooster, BTH Maassen, JC Stam, PW Hermans, MR Ten Haaft, ... Journal of immunological methods 324 (1-2), 1-12, 2007 | 100 | 2007 |
Reliable and controllable antibody fragment selections from Camelid non-immune libraries for target validation P Verheesen, A Roussis, HJ de Haard, AJ Groot, JC Stam, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1764 (8), 1307-1319, 2006 | 85 | 2006 |
VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation HH Versteeg, BB Sørensen, SH Slofstra, JHM Van den Brande, JC Stam, ... Journal of Biological Chemistry 277 (30), 27065-27072, 2002 | 73 | 2002 |
The DH protein family, exchange factors for Rho-like GTPases JC Stam, JG Collard Cytoskeleton and Small G Proteins, 51-83, 1999 | 66 | 1999 |
Targeted biomarker discovery by high throughput glycosylation profiling of human plasma alpha1-antitrypsin and immunoglobulin A LR Ruhaak, CAM Koeleman, HW Uh, JC Stam, D van Heemst, AB Maier, ... PloS one 8 (9), e73082, 2013 | 47 | 2013 |
Llama single-chain antibody that blocks lipopolysaccharide binding and signaling: prospects for therapeutic applications M El Khattabi, H Adams, E Heezius, P Hermans, F Detmers, B Maassen, ... Clinical and vaccine immunology 13 (10), 1079-1086, 2006 | 46 | 2006 |
Pleckstrin homology domains and phospholipid-induced cytoskeletal reorganization AD Ma, CS Abrams Thrombosis and haemostasis 82 (08), 399-406, 1999 | 44 | 1999 |
Specific immuno capturing of the staphylococcal superantigen toxic‐shock syndrome toxin‐1 in plasma H Adams, W Brummelhuis, B Maassen, N van Egmond, ME Khattabi, ... Biotechnology and bioengineering 104 (1), 143-151, 2009 | 29 | 2009 |
Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor M Schenning, CM van Tiel, D Van Manen, JC Stam, BM Gadella, ... Journal of lipid research 45 (8), 1555-1564, 2004 | 26 | 2004 |
The v-Crk oncogene enhances cell survival and induces activation of protein kinase B/Akt JC Stam, WJC Geerts, HH Versteeg, AJ Verkleij, PMPB en Henegouwen Journal of Biological Chemistry 276 (27), 25176-25183, 2001 | 26 | 2001 |