The chemokine receptor CX3CR1 defines three antigen-experienced CD8 T cell subsets with distinct roles in immune surveillance and homeostasis C Gerlach, EA Moseman, SM Loughhead, D Alvarez, AJ Zwijnenburg, ... Immunity 45 (6), 1270-1284, 2016 | 519 | 2016 |
Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex H Prüss, A Tedeschi, A Thiriot, L Lynch, SM Loughhead, S Stutte, IB Mazo, ... Nature neuroscience 20 (11), 1549-1559, 2017 | 169 | 2017 |
Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo T DiTommaso, JM Cole, L Cassereau, JA Buggé, JLS Hanson, ... Proceedings of the National Academy of Sciences 115 (46), E10907-E10914, 2018 | 162 | 2018 |
Antigen availability determines CD8+ T cell-dendritic cell interaction kinetics and memory fate decisions SE Henrickson, M Perro, SM Loughhead, B Senman, S Stutte, M Quigley, ... Immunity 39 (3), 496-507, 2013 | 159 | 2013 |
Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity D Zemmour, A Pratama, SM Loughhead, D Mathis, C Benoist Proceedings of the National Academy of Sciences 114 (17), E3472-E3480, 2017 | 146 | 2017 |
Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice Y Liu, NV Belkina, C Park, R Nambiar, SM Loughhead, G Patino-Lopez, ... Blood, The Journal of the American Society of Hematology 119 (2), 445-453, 2012 | 113 | 2012 |
Targeted delivery of immunomodulators to lymph nodes J Azzi, Q Yin, M Uehara, S Ohori, L Tang, K Cai, T Ichimura, M McGrath, ... Cell reports 15 (6), 1202-1213, 2016 | 99 | 2016 |
Polyfunctional CD4+ T Cell Responses to Immunodominant Epitopes Correlate with Disease Activity of Virulent Salmonella M Maybeno, A Redeker, SPM Welten, B Peters, SM Loughhead, ... Public Library of Science 7 (8), e43481, 2012 | 30 | 2012 |
Microfluidic squeezing enables MHC class I antigen presentation by diverse immune cells to elicit CD8+ T cell responses with antitumor activity MG Booty, KA Hlavaty, A Stockmann, EI Ozay, C Smith, L Tian, E How, ... The Journal of Immunology 208 (4), 929-940, 2022 | 13 | 2022 |
Intracellular delivery of biomolecules to induce tolerance JB Gilbert, W Bu, S Loughhead, H Bernstein, AR Sharei, F Moore US Patent App. 16/098,404, 2019 | 8 | 2019 |
Cell Squeeze: driving more effective CD8 T-cell activation through cytosolic antigen delivery JC Park, H Bernstein, S Loughhead, R Zwirtes, J Jennings, V Nicolini, ... Immuno-Oncology and Technology 16, 100091, 2022 | 6 | 2022 |
Initial results of a first-in-human, dose escalation study of a cell-based vaccine in HLA A* 02+ patients (pts) with recurrent, locally advanced or metastatic HPV16+ solid … A Jimeno, JC Baranda, MM Mita, MS Gordon, MH Taylor, WT Iams, ... Journal of Clinical Oncology 39 (15_suppl), 2536-2536, 2021 | 6 | 2021 |
Figuring fact from fiction: unbiased polling of memory T cells C Gerlach, SM Loughhead, UH von Andrian Cell 161 (4), 702-704, 2015 | 5 | 2015 |
Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice K Blagovic, CK Smith, A Ramakrishnan, L Moore, DR Soto, Z Thompson, ... Frontiers in Immunology 13, 1015585, 2022 | 4 | 2022 |
Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A* 02+ patients with HPV16+ solid tumors A Jimeno, J Baranda, WT Iams, JC Park, M Mita, MS Gordon, M Taylor, ... Investigational new drugs 41 (2), 284-295, 2023 | 3 | 2023 |
48MO SQZ-PBMC-HPV-101: Preliminary results of a first-in-human, dose-escalation study of a cell-based vaccine in HLA A* 02+ patients with recurrent, locally advanced, or … JC Park, JC Baranda, MM Mita, WT Iams, MS Gordon, M Taylor, N Dhani, ... Annals of Oncology 32, S1393, 2021 | 3 | 2021 |
Intracellular delivery of biomolecules to induce tolerance S Loughhead, JB Gilbert, H Bernstein, AR Sharei, F Moore US Patent App. 16/098,405, 2021 | 3 | 2021 |
Intracellular delivery of biomolecules to modify immune response S Loughhead, L Talarico, A Vicente-Suarez, M Booty, H Bernstein, ... US Patent App. 16/980,339, 2021 | 3 | 2021 |
Methods for treating hpv-associated diseases S Loughhead, L Talarico, A Vicente-Suarez, M Booty, H Bernstein, ... US Patent App. 16/980,341, 2021 | 3 | 2021 |
169 Microfluidics cell squeezing enables human PBMCs as drivers of antigen-specific CD8 T responses across broad range of antigens for diverse clinical applications M Maloney, S Loughhead, A Ramakrishnan, C Smith, A Venkitaraman, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 3 | 2020 |