Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes V Lyssenko, R Lupi, P Marchetti, S Del Guerra, M Orho-Melander, ... The Journal of clinical investigation 117 (8), 2155-2163, 2007 | 1089 | 2007 |
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that β-cell death is caspase mediated, partially dependent … R Lupi, F Dotta, L Marselli, S Del Guerra, M Masini, C Santangelo, ... Diabetes 51 (5), 1437-1442, 2002 | 858 | 2002 |
Functional and molecular defects of pancreatic islets in human type 2 diabetes S Del Guerra, R Lupi, L Marselli, M Masini, M Bugliani, S Sbrana, S Torri, ... Diabetes 54 (3), 727-735, 2005 | 599 | 2005 |
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion C Ling, S Del Guerra, R Lupi, T Rönn, C Granhall, H Luthman, P Masiello, ... Diabetologia 51, 615-622, 2008 | 568 | 2008 |
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients M Volkmar, S Dedeurwaerder, DA Cunha, MN Ndlovu, M Defrance, ... The EMBO journal 31 (6), 1405-1426, 2012 | 483 | 2012 |
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin P Marchetti, S Del Guerra, L Marselli, R Lupi, M Masini, M Pollera, ... The Journal of Clinical Endocrinology & Metabolism 89 (11), 5535-5541, 2004 | 452 | 2004 |
Autophagy in human type 2 diabetes pancreatic beta cells M Masini, M Bugliani, R Lupi, S Del Guerra, U Boggi, F Filipponi, ... Diabetologia 52, 1083-1086, 2009 | 410 | 2009 |
A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets P Marchetti, R Lupi, M Bugliani, CL Kirkpatrick, G Sebastiani, FA Grieco, ... Diabetologia 55, 3262-3272, 2012 | 271 | 2012 |
Lipotoxicity in human pancreatic islets and the protective effect of metformin R Lupi, S Del Guerra, V Fierabracci, L Marselli, M Novelli, G Patane, ... Diabetes 51 (suppl_1), S134-S137, 2002 | 240 | 2002 |
Multilayer nanoencapsulation. New approach for immune protection of human pancreatic islets S Krol, S del Guerra, M Grupillo, A Diaspro, A Gliozzi, P Marchetti Nano letters 6 (9), 1933-1939, 2006 | 224 | 2006 |
Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARγ2 in the modulation of insulin secretion R Lupi, S Del Guerra, L Marselli, M Bugliani, U Boggi, F Mosca, ... American Journal of Physiology-Endocrinology and Metabolism 286 (4), E560-E567, 2004 | 203 | 2004 |
Gliclazide protects human islet beta‐cells from apoptosis induced by intermittent high glucose S Del Guerra, M Grupillo, M Masini, R Lupi, M Bugliani, S Torri, U Boggi, ... Diabetes/metabolism research and reviews 23 (3), 234-238, 2007 | 192 | 2007 |
Hepatitis C virus infection and human pancreatic β-cell dysfunction M Masini, D Campani, U Boggi, M Menicagli, N Funel, M Pollera, R Lupi, ... Diabetes care 28 (4), 940-941, 2005 | 181 | 2005 |
A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects G Sesti, M Cardellini, MA Marini, S Frontoni, M D’Adamo, S Del Guerra, ... Diabetes 52 (5), 1280-1283, 2003 | 181 | 2003 |
The E23K Variant of KCNJ11 Encoding the Pancreatic β-Cell Adenosine 5′-Triphosphate-Sensitive Potassium Channel Subunit Kir6.2 Is Associated with an … G Sesti, E Laratta, M Cardellini, F Andreozzi, S Del Guerra, C Irace, ... The Journal of Clinical Endocrinology & Metabolism 91 (6), 2334-2339, 2006 | 174 | 2006 |
Insulin Secretory Function Is Impaired in Isolated Human Islets Carrying the Gly972→Arg IRS-1 Polymorphism P Marchetti, R Lupi, M Federici, L Marselli, M Masini, U Boggi, ... Diabetes 51 (5), 1419-1424, 2002 | 155 | 2002 |
Increased O‐glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic β‐cells C D'Alessandris, F Andreozzi, M Federici, M Cardellini, A Brunetti, ... The FASEB journal 18 (9), 959-961, 2004 | 132 | 2004 |
The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets R Lupi, S Del Guerra, M Bugliani, U Boggi, F Mosca, S Torri, S Del Prato, ... European journal of endocrinology 154 (2), 355-361, 2006 | 126 | 2006 |
The β-cell in human type 2 diabetes P Marchetti, R Lupi, S Del Guerra, M Bugliani, L Marselli, U Boggi The Islets of Langerhans, 501-514, 2010 | 118 | 2010 |
Effects of prolonged in vitro exposure to sulphonylureas on the function and survival of human islets S Del Guerra, L Marselli, R Lupi, U Boggi, F Mosca, L Benzi, S Del Prato, ... Journal of Diabetes and its Complications 19 (1), 60-64, 2005 | 103 | 2005 |