| Identification of VAPA and VAPB as Kv2 channel-interacting proteins defining endoplasmic reticulum–plasma membrane junctions in mammalian brain neurons M Kirmiz, NC Vierra, S Palacio, JS Trimmer Journal of Neuroscience 38 (35), 7562-7584, 2018 | 114 | 2018 |
| β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions L Zhu, J Almaça, PK Dadi, H Hong, W Sakamoto, M Rossi, RJ Lee, ... Nature communications 8 (1), 14295, 2017 | 87 | 2017 |
| Kv2. 1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons NC Vierra, M Kirmiz, D van der List, LF Santana, JS Trimmer Elife 8, e49953, 2019 | 81 | 2019 |
| Inhibition of pancreatic β-cell Ca2+/calmodulin-dependent protein kinase II reduces glucose-stimulated calcium influx and insulin secretion, impairing glucose tolerance PK Dadi, NC Vierra, A Ustione, DW Piston, RJ Colbran, DA Jacobson Journal of Biological Chemistry 289 (18), 12435-12445, 2014 | 71 | 2014 |
| Type 2 Diabetes–Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis NC Vierra, PK Dadi, I Jeong, M Dickerson, DR Powell, DA Jacobson Diabetes 64 (11), 3818-3828, 2015 | 69 | 2015 |
| Glucocorticoids reprogram β-cell signaling to preserve insulin secretion NHF Fine, CL Doig, YS Elhassan, NC Vierra, P Marchetti, M Bugliani, ... Diabetes 67 (2), 278-290, 2018 | 65 | 2018 |
| Pancreatic β-Cell–specific Ablation of TASK-1 Channels Augments Glucose-stimulated Calcium Entry and Insulin Secretion, Improving Glucose Tolerance PK Dadi, NC Vierra, DA Jacobson Endocrinology 155 (10), 3757-3768, 2014 | 48 | 2014 |
| TASK-1 potassium channels limit pancreatic α-cell calcium influx and glucagon secretion PK Dadi, B Luo, NC Vierra, DA Jacobson Molecular Endocrinology 29 (5), 777-787, 2015 | 45 | 2015 |
| Selective small molecule activators of TREK-2 channels stimulate dorsal root ganglion c-fiber nociceptor two-pore-domain potassium channel currents and limit calcium influx PK Dadi, NC Vierra, E Days, MT Dickerson, PN Vinson, CD Weaver, ... ACS chemical neuroscience 8 (3), 558-568, 2017 | 40 | 2017 |
| TALK-1 channels control β cell endoplasmic reticulum Ca2+ homeostasis NC Vierra, PK Dadi, SC Milian, MT Dickerson, KL Jordan, P Gilon, ... Science signaling 10 (497), eaan2883, 2017 | 32 | 2017 |
| TALK-1 reduces delta-cell endoplasmic reticulum and cytoplasmic calcium levels limiting somatostatin secretion NC Vierra, MT Dickerson, KL Jordan, PK Dadi, KA Katdare, MK Altman, ... Molecular metabolism 9, 84-97, 2018 | 27 | 2018 |
| Regulation of neuronal excitation–transcription coupling by Kv2.1-induced clustering of somatic L-type Ca2+ channels at ER-PM junctions NC Vierra, SC O’Dwyer, C Matsumoto, LF Santana, JS Trimmer Proceedings of the National Academy of Sciences 118 (46), e2110094118, 2021 | 25 | 2021 |
| Osteopontin activates the diabetes-associated potassium channel TALK-1 in pancreatic β-cells MT Dickerson, NC Vierra, SC Milian, PK Dadi, DA Jacobson PloS one 12 (4), e0175069, 2017 | 21 | 2017 |
| Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant NA Hawkins, SN Misra, M Jurado, SK Kang, NC Vierra, K Nguyen, L Wren, ... Neurobiology of disease 147, 105141, 2021 | 18 | 2021 |
| Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion MT Dickerson, PK Dadi, MK Altman, KR Verlage, AS Thorson, KL Jordan, ... American Journal of Physiology-Endocrinology and Metabolism 316 (4), E646-E659, 2019 | 16 | 2019 |
| Ion Channel Partnerships: odd and not-so-odd couples controlling neuronal ion channel function NC Vierra, JS Trimmer International journal of molecular sciences 23 (4), 1953, 2022 | 12 | 2022 |
| NPC1-dependent alterations in KV2.1–CaV1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease M Casas, KD Murray, K Hino, NC Vierra, S Simó, JS Trimmer, RE Dixon, ... Nature Communications 14 (1), 4553, 2023 | 5 | 2023 |
| Neuronal ER-plasma membrane junctions couple excitation to Ca2+-activated PKA signaling NC Vierra, L Ribeiro-Silva, M Kirmiz, D Van Der List, P Bhandari, ... Nature communications 14 (1), 5231, 2023 | 4 | 2023 |
| Simultaneous Real-Time Measurement of the β-Cell Membrane Potential and Ca2+ Influx to Assess the Role of Potassium Channels on β-Cell Function NC Vierra, MT Dickerson, LH Philipson, DA Jacobson Potassium Channels: Methods and Protocols, 73-84, 2018 | 3 | 2018 |
| The formation of KV2.1 macro-clusters is required for sex-specific differences in L-type CaV1.2 clustering and function in arterial myocytes C Matsumoto, SC O’Dwyer, D Manning, G Hernandez-Hernandez, ... Communications Biology 6 (1), 1165, 2023 | 2 | 2023 |
