Role of mitochondrial reverse electron transport in ROS signaling: potential roles in health and disease F Scialò, DJ Fernández-Ayala, A Sanz Frontiers in physiology 8, 273331, 2017 | 464 | 2017 |
Mitochondrial ROS produced via reverse electron transport extend animal lifespan F Scialo, A Sriram, D Fernandez-Ayala, N Gubina, M Lohmus, G Nelson, ... Cell metabolism 23 (4), 725-734, 2016 | 357 | 2016 |
Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation DJM Fernandez-Ayala, A Sanz, S Vartiainen, KK Kemppainen, ... Cell metabolism 9 (5), 449-460, 2009 | 185 | 2009 |
Mitochondrial ROS production correlates with, but does not directly regulate lifespan in Drosophila A Sanz, DJM Fernández-Ayala, RKA Stefanatos, HT Jacobs Aging (Albany NY) 2 (4), 200, 2010 | 137 | 2010 |
Age-related mitochondrial dysfunction as a key factor in COVID-19 disease DJM Fernández-Ayala, P Navas, G López-Lluch Experimental gerontology 142, 111147, 2020 | 106 | 2020 |
Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines G Brea-Calvo, Á Rodríguez-Hernández, DJM Fernández-Ayala, P Navas, ... Free Radical Biology and Medicine 40 (8), 1293-1302, 2006 | 99 | 2006 |
Gene expression in a Drosophila model of mitochondrial disease DJM Fernandez-Ayala, S Chen, E Kemppainen, KMC O'Dell, HT Jacobs PloS one 5 (1), e8549, 2010 | 86 | 2010 |
Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity S Padilla, T Jonassen, MA Jiménez-Hidalgo, DJM Fernández-Ayala, ... Journal of Biological Chemistry 279 (25), 25995-26004, 2004 | 79 | 2004 |
Role of plasma membrane coenzyme Q on the regulation of apoptosis G López‐Lluch, MP Barroso, SF Martin, DJM Fernández‐Ayala, ... Biofactors 9 (2‐4), 171-177, 1999 | 76 | 1999 |
Coenzyme Q distribution in HL-60 human cells depends on the endomembrane system DJM Fernández-Ayala, G Brea-Calvo, G López-Lluch, P Navas Biochimica et Biophysica Acta (BBA)-Biomembranes 1713 (2), 129-137, 2005 | 75 | 2005 |
Mitochondrial responsibility in ageing process: innocent, suspect or guilty G López-Lluch, C Santos-Ocaña, JA Sánchez-Alcázar, ... Biogerontology 16, 599-620, 2015 | 72 | 2015 |
Ceramide-dependent caspase 3 activation is prevented by coenzyme Q from plasma membrane in serum-deprived cells P Navas, DM Fernandez-Ayala, SF Martin, G Lopez-Lluch, R De Cabo, ... Free radical research 36 (4), 369-374, 2002 | 71 | 2002 |
The apoptotic microtubule network preserves plasma membrane integrity during the execution phase of apoptosis JA Sánchez-Alcázar, Á Rodríguez-Hernández, MD Cordero, ... Apoptosis 12, 1195-1208, 2007 | 62 | 2007 |
Biochemical Assessment of Coenzyme Q10 Deficiency JC Rodríguez-Aguilera, AB Cortés, DJM Fernández-Ayala, P Navas Journal of clinical medicine 6 (3), 27, 2017 | 61 | 2017 |
Specificity of coenzyme Q10 for a balanced function of respiratory chain and endogenous ubiquinone biosynthesis in human cells DJM Fernández-Ayala, G López-Lluch, M García-Valdés, A Arroyo, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1706 (1-2), 174-183, 2005 | 61 | 2005 |
Coenzyme Q protects cells against serum withdrawal-induced apoptosis by inhibition of ceramide release and caspase-3 activation DJM Fernández-Ayala, SF Martín, MP Barroso, C Gómez-Díaz, ... Antioxidants & redox signaling 2 (2), 263-275, 2000 | 58 | 2000 |
Mitochondrial dysfunction in metabolism and ageing: shared mechanisms and outcomes? G López-Lluch, JD Hernández-Camacho, DJM Fernández-Ayala, ... Biogerontology 19, 461-480, 2018 | 54 | 2018 |
Nuclear caspase-3 and capase-7 activation, and poly (ADP-ribose) polymerase cleavage are early events in camptothecin-induced apoptosis Á Rodríguez-Hernández, G Brea-Calvo, DJM Fernández-Ayala, ... Apoptosis 11, 131-139, 2006 | 53 | 2006 |
Mitochondrial disease in flies HT Jacobs, DJM Fernández-Ayala, S Manjiry, E Kemppainen, ... Biochimica et biophysica acta (BBA)-Bioenergetics 1659 (2-3), 190-196, 2004 | 38 | 2004 |
The mitochondrial phosphatase PPTC7 orchestrates mitochondrial metabolism regulating coenzyme Q10 biosynthesis I González-Mariscal, A Martin-Montalvo, L Vazquez-Fonseca, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (11), 1235-1248, 2018 | 35 | 2018 |