Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α–ZEB1 axis JV Joseph, S Conroy, K Pavlov, P Sontakke, T Tomar, E Eggens-Meijer, ... Cancer letters 359 (1), 107-116, 2015 | 331 | 2015 |
TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion JV Joseph, S Conroy, T Tomar, E Eggens-Meijer, K Bhat, S Copray, ... Cell death & disease 5 (10), e1443-e1443, 2014 | 202 | 2014 |
TGF-β as a therapeutic target in high grade gliomas–promises and challenges JV Joseph, V Balasubramaniyan, A Walenkamp, FAE Kruyt Biochemical pharmacology 85 (4), 478-485, 2013 | 187 | 2013 |
EMT‐and MET‐related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities UD Kahlert, JV Joseph, FAE Kruyt Molecular oncology 11 (7), 860-877, 2017 | 143 | 2017 |
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation E Eskilsson, GV Rosland, KM Talasila, S Knappskog, O Keunen, ... Neuro-oncology 18 (12), 1644-1655, 2016 | 113 | 2016 |
The angiogenic switch leads to a metabolic shift in human glioblastoma KM Talasila, GV Røsland, HR Hagland, E Eskilsson, IH Flønes, S Fritah, ... Neuro-oncology 19 (3), 383-393, 2017 | 72 | 2017 |
The cGAS-STING pathway is a therapeutic target in a preclinical model of hepatocellular carcinoma MK Thomsen, MK Skouboe, C Boularan, F Vernejoul, T Lioux, SL Leknes, ... Oncogene 39 (8), 1652-1664, 2020 | 70 | 2020 |
TGF-β promotes microtube formation in glioblastoma through thrombospondin 1 JV Joseph, CR Magaut, S Storevik, LH Geraldo, T Mathivet, MA Latif, ... Neuro-oncology 24 (4), 541-553, 2022 | 63 | 2022 |
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity DC Watson, D Bayik, S Storevik, SS Moreino, SA Sprowls, J Han, ... Nature cancer 4 (5), 648-664, 2023 | 57 | 2023 |
Glioblastoma stem-like cells are more susceptible than differentiated cells to natural killer cell lysis mediated through killer immunoglobulin-like receptors–human leukocyte … HN Haspels, MA Rahman, JV Joseph, A Gras Navarro, M Chekenya Frontiers in immunology 9, 1345, 2018 | 57 | 2018 |
Serum-induced differentiation of glioblastoma neurospheres leads to enhanced migration/invasion capacity that is associated with increased MMP9 JV Joseph, IAM Roosmalen, E Busschers, T Tomar, S Conroy, ... PLoS One 10 (12), e0145393, 2015 | 49 | 2015 |
Subclassification of newly diagnosed glioblastomas through an immunohistochemical approach S Conroy, FAE Kruyt, JV Joseph, V Balasubramaniyan, KP Bhat, ... PloS one 9 (12), e115687, 2014 | 43 | 2014 |
Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma JA Hossain, MA Latif, LAR Ystaas, S Ninzima, K Riecken, A Muller, ... Neuro-oncology 21 (7), 890-900, 2019 | 34 | 2019 |
Pretreatment of glioblastoma with bortezomib potentiates natural killer cell cytotoxicity through TRAIL/DR5 mediated apoptosis and prolongs animal survival A Gras Navarro, H Espedal, JV Joseph, L Trachsel-Moncho, M Bahador, ... Cancers 11 (7), 996, 2019 | 31 | 2019 |
Inhibition of formyl peptide receptor in high-grade astrocytoma by CHemotaxis Inhibitory Protein of S. aureus JC Boer, UM Domanska, H Timmer-Bosscha, IGJ Boer, CJC De Haas, ... British journal of cancer 108 (3), 587-596, 2013 | 31 | 2013 |
The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma IAM van Roosmalen, CR Reis, R Setroikromo, S Yuvaraj, JV Joseph, ... Springerplus 3, 1-12, 2014 | 21 | 2014 |
Three-dimensional culture models to study glioblastoma—Current trends and future perspectives JV Joseph, MS Blaavand, T Daubon, FAE Kruyt, MK Thomsen Current Opinion in Pharmacology 61, 91-97, 2021 | 19 | 2021 |
Comparative Analysis of Stk11/Lkb1 versus Pten Deficiency in Lung Adenocarcinoma Induced by CRISPR/Cas9 MHVMKT Martin F. Berthelsen, Siv L. Leknes, Maria Riedel, Mette A. Pedersen ... Cancers, 2021 | 15 | 2021 |
Microenvironment involved in FPR1 expression by human glioblastomas JC Boer, DMS van Marion, JV Joseph, NM Kliphuis, H Timmer-Bosscha, ... Journal of Neuro-oncology 123, 53-63, 2015 | 15 | 2015 |
STING activation counters glioblastoma by vascular alteration and immune surveillance Cancer Letters, 2023 | 5 | 2023 |