A host-produced quorum-sensing autoinducer controls a phage lysis-lysogeny decision JE Silpe, BL Bassler Cell 176 (1), 268-280. e13, 2019 | 307 | 2019 |
A Vibrio cholerae autoinducer–receptor pair that controls biofilm formation K Papenfort, JE Silpe, KR Schramma, JP Cong, MR Seyedsayamdost, ... Nature chemical biology 13 (5), 551-557, 2017 | 197 | 2017 |
Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic TP Thomas, B Huang, SK Choi, JE Silpe, A Kotlyar, AM Desai, H Zong, ... Molecular pharmaceutics 9 (9), 2669-2676, 2012 | 159 | 2012 |
Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface SK Choi, A Myc, JE Silpe, M Sumit, PT Wong, K McCarthy, AM Desai, ... ACS nano 7 (1), 214-228, 2013 | 146 | 2013 |
A photochemical approach for controlled drug release in targeted drug delivery SK Choi, M Verma, J Silpe, RE Moody, K Tang, JJ Hanson, JR Baker Jr Bioorganic & medicinal chemistry 20 (3), 1281-1290, 2012 | 92 | 2012 |
Avidity modulation of folate-targeted multivalent dendrimers for evaluating biophysical models of cancer targeting nanoparticles JE Silpe, M Sumit, TP Thomas, B Huang, A Kotlyar, MA Van Dongen, ... ACS chemical biology 8 (9), 2063-2071, 2013 | 72 | 2013 |
Avidity mechanism of dendrimer–folic acid conjugates MA Van Dongen, JE Silpe, CA Dougherty, AK Kanduluru, SK Choi, BG Orr, ... Molecular pharmaceutics 11 (5), 1696-1706, 2014 | 71 | 2014 |
Development of Potent Inhibitors of Pyocyanin Production in Pseudomonas aeruginosa LC Miller, CT O’Loughlin, Z Zhang, A Siryaporn, JE Silpe, BL Bassler, ... Journal of medicinal chemistry 58 (3), 1298-1306, 2015 | 69 | 2015 |
Bubble-driven detachment of bacteria from confined microgeometries S Khodaparast, MK Kim, JE Silpe, HA Stone Environmental science & technology 51 (3), 1340-1347, 2017 | 67 | 2017 |
The bacterial toxin colibactin triggers prophage induction JE Silpe, JWH Wong, SV Owen, M Baym, EP Balskus Nature 603 (7900), 315-320, 2022 | 58 | 2022 |
Phage-encoded LuxR-type receptors responsive to host-produced bacterial quorum-sensing autoinducers JE Silpe, BL Bassler MBio 10 (2), 10.1128/mbio. 00638-19, 2019 | 52 | 2019 |
Poly (amidoamine) dendrimer–methotrexate conjugates: the mechanism of interaction with folate binding protein MA van Dongen, R Rattan, J Silpe, C Dougherty, NL Michmerhuizen, ... Molecular pharmaceutics 11 (11), 4049-4058, 2014 | 43 | 2014 |
Separating functions of the phage-encoded quorum-sensing-activated antirepressor Qtip JE Silpe, AA Bridges, X Huang, DR Coronado, OP Duddy, BL Bassler Cell host & microbe 27 (4), 629-641. e4, 2020 | 36 | 2020 |
Mechanism underlying autoinducer recognition in the Vibrio cholerae DPO-VqmA quorum-sensing pathway X Huang, OP Duddy, JE Silpe, JE Paczkowski, J Cong, BR Henke, ... Journal of Biological Chemistry 295 (10), 2916-2931, 2020 | 33 | 2020 |
Design and in vitro validation of multivalent dendrimer methotrexates as a folate-targeting anticancer therapeutic T P Thomas, M Joice, M Sumit, J E Silpe, A Kotlyar, S Bharathi, ... Current pharmaceutical design 19 (37), 6594-6605, 2013 | 30 | 2013 |
Generation of antibubbles from core–shell double emulsion templates produced by microfluidics JE Silpe, JK Nunes, AT Poortinga, HA Stone Langmuir 29 (28), 8782-8787, 2013 | 29 | 2013 |
Deciphering human microbiota–host chemical interactions JE Silpe, EP Balskus ACS Central Science 7 (1), 20-29, 2020 | 27 | 2020 |
Magnetic antibubbles: Formation and control of magnetic macroemulsions for fluid transport applications JE Silpe, DW McGrail Journal of Applied Physics 113 (17), 2013 | 19 | 2013 |
Small protein modules dictate prophage fates during polylysogeny JE Silpe, OP Duddy, GE Johnson, GA Beggs, FA Hussain, KJ Forsberg, ... Nature 620 (7974), 625-633, 2023 | 15 | 2023 |
Natural and synthetic inhibitors of a phage-encoded quorum-sensing receptor affect phage–host dynamics in mixed bacterial communities JE Silpe, OP Duddy, BL Bassler Proceedings of the National Academy of Sciences 119 (49), e2217813119, 2022 | 13 | 2022 |