The trans-ancestral genomic architecture of glycemic traits J Chen, CN Spracklen, G Marenne, A Varshney, LJ Corbin, J Luan, ... Nature genetics 53 (6), 840-860, 2021 | 407 | 2021 |
Genetic regulatory signatures underlying islet gene expression and type 2 diabetes A Varshney, LJ Scott, RP Welch, MR Erdos, PS Chines, N Narisu, ... Proceedings of the National Academy of Sciences 114 (9), 2301-2306, 2017 | 202 | 2017 |
Strategies to develop endogenous stem cell-recruiting bioactive materials for tissue repair and regeneration S Pacelli, S Basu, J Whitlow, A Chakravarti, F Acosta, A Varshney, ... Advanced drug delivery reviews 120, 50-70, 2017 | 133 | 2017 |
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D A Viñuela, A Varshney, M van de Bunt, RB Prasad, O Asplund, A Bennett, ... Nature communications 11 (1), 4912, 2020 | 103 | 2020 |
Super enhancers in cancers, complex disease, and developmental disorders AR Niederriter, A Varshney, SCJ Parker, DM Martin Genes 6 (4), 1183-1200, 2015 | 86 | 2015 |
Multiomic profiling identifies cis-regulatory networks underlying human pancreatic β cell identity and function N Lawlor, EJ Marquez, P Orchard, N Narisu, MS Shamim, A Thibodeau, ... Cell reports 26 (3), 788-801. e6, 2019 | 72 | 2019 |
A Type 2 Diabetes–Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5 Locus TS Roman, ME Cannon, S Vadlamudi, ML Buchkovich, BN Wolford, ... Diabetes 66 (9), 2521-2530, 2017 | 65 | 2017 |
BoostMe accurately predicts DNA methylation values in whole-genome bisulfite sequencing of multiple human tissues LS Zou, MR Erdos, DL Taylor, PS Chines, A Varshney, ... BMC genomics 19, 1-15, 2018 | 41 | 2018 |
Human and rat skeletal muscle single-nuclei multi-omic integrative analyses nominate causal cell types, regulatory elements, and SNPs for complex traits P Orchard, N Manickam, C Ventresca, S Vadlamudi, A Varshney, V Rai, ... Genome Research 31 (12), 2258-2275, 2021 | 33 | 2021 |
Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC). The trans-ancestral genomic architecture of glycemic traits J Chen, CN Spracklen, G Marenne, Lifelines Cohort Study Nat Genet 53 (6), 840-860, 2021 | 28 | 2021 |
Chromatin information content landscapes inform transcription factor and DNA interactions R D’Oliveira Albanus, Y Kyono, J Hensley, A Varshney, P Orchard, ... Nature Communications 12 (1), 1307, 2021 | 25 | 2021 |
Interactions between genetic variation and cellular environment in skeletal muscle gene expression DL Taylor, DA Knowles, LJ Scott, AH Ramirez, FP Casale, BN Wolford, ... PLoS One 13 (4), e0195788, 2018 | 21 | 2018 |
Cell specificity of human regulatory annotations and their genetic effects on gene expression A Varshney, H VanRenterghem, P Orchard, AP Boyle, ML Stitzel, D Ucar, ... Genetics 211 (2), 549-562, 2019 | 19 | 2019 |
Influence of genetic variants on gene expression in human pancreatic islets–implications for type 2 diabetes A Viñuela, A Varshney, M van de Bunt, RB Prasad, O Asplund, A Bennett, ... BioRxiv, 655670, 2019 | 17 | 2019 |
Non-invasive blood analysis C Elliott, ME Jones, A Varshney, M Ruegg US Patent App. 14/767,772, 2016 | 16 | 2016 |
Loci for insulin processing and secretion provide insight into type 2 diabetes risk KA Broadaway, X Yin, A Williamson, VA Parsons, EP Wilson, AH Moxley, ... The American Journal of Human Genetics 110 (2), 284-299, 2023 | 14 | 2023 |
Rare non-coding variation identified by large scale whole genome sequencing reveals unexplained heritability of type 2 diabetes J Wessel, TD Majarian, HM Highland, S Raghavan, MD Szeto, ... MedRxiv, 2020.11. 13.20221812, 2020 | 13 | 2020 |
A transcription start site map in human pancreatic islets reveals functional regulatory signatures A Varshney, Y Kyono, VR Elangovan, C Wang, MR Erdos, N Narisu, ... Diabetes 70 (7), 1581-1591, 2021 | 11 | 2021 |
Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis AP Tenney, SA Di Gioia, BD Webb, WM Chan, E de Boer, SJ Garnai, ... Nature genetics 55 (7), 1149-1163, 2023 | 9 | 2023 |
RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes JT Walker, DC Saunders, V Rai, C Dai, P Orchard, AL Hopkirk, ... BioRxiv, 2021.12. 16.466282, 2021 | 9 | 2021 |