关注
Manfred Koegl
Manfred Koegl
Boehringer Ingelheim
在 aon.at 的电子邮件经过验证
标题
引用次数
引用次数
年份
A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly
M Koegl, T Hoppe, S Schlenker, HD Ulrich, TU Mayer, S Jentsch
Cell 96 (5), 635-644, 1999
14541999
The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors
S Pfefferle, J Schöpf, M Kögl, CC Friedel, MA Müller, J Carbajo-Lozoya, ...
PLoS pathogens 7 (10), e1002331, 2011
4562011
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
W Farnaby, M Koegl, MJ Roy, C Whitworth, E Diers, N Trainor, D Zollman, ...
Nature chemical biology 15 (7), 672-680, 2019
4222019
Drugging an undruggable pocket on KRAS
D Kessler, M Gmachl, A Mantoulidis, LJ Martin, A Zoephel, M Mayer, ...
Proceedings of the National Academy of Sciences 116 (32), 15823-15829, 2019
3742019
The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors.
S Roche, M Koegl, SA Courtneidge
Proceedings of the National Academy of Sciences 91 (19), 9185-9189, 1994
3521994
Csk inhibition of c‐Src activity requires both the SH2 and SH3 domains of Src.
G Superti‐Furga, S Fumagalli, M Koegl, SA Courtneidge, G Draetta
The EMBO journal 12 (7), 2625-2634, 1993
3311993
DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases
S Roche, M Koegl, MV Barone, MF Roussel, SA Courtneidge
Molecular and cellular biology 15 (2), 1102-1109, 1995
2911995
Iterative design and optimization of initially inactive proteolysis targeting chimeras (PROTACs) identify VZ185 as a potent, fast, and selective von Hippel–Lindau (VHL) based …
V Zoppi, SJ Hughes, C Maniaci, A Testa, T Gmaschitz, C Wieshofer, ...
Journal of medicinal chemistry 62 (2), 699-726, 2018
2822018
CEP152 is a genome maintenance protein disrupted in Seckel syndrome
E Kalay, G Yigit, Y Aslan, KE Brown, E Pohl, LS Bicknell, H Kayserili, Y Li, ...
Nature genetics 43 (1), 23-26, 2011
2702011
Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif
M Koegl, P Zlatkine, SC Ley, SA Courtneidge, AI Magee
Biochemical Journal 303 (3), 749-753, 1994
2691994
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome
MJ Taussig, O Stoevesandt, CAK Borrebaeck, AR Bradbury, D Cahill, ...
Nature methods 4 (1), 13-17, 2007
2582007
Sequence Requirements for Binding of Src Family Tyrosine Kinases to Activated Growth Factor Receptors (∗)
G Alonso, M Koegl, N Mazurenko, SA Courtneidge
Journal of Biological Chemistry 270 (17), 9840-9848, 1995
2421995
Evolutionarily conserved herpesviral protein interaction networks
E Fossum, CC Friedel, SV Rajagopala, B Titz, A Baiker, T Schmidt, ...
PLoS pathogens 5 (9), e1000570, 2009
2292009
Structure-based design of an in vivo active selective BRD9 inhibitor
LJ Martin, M Koegl, G Bader, XL Cockcroft, O Fedorov, D Fiegen, ...
Journal of medicinal chemistry 59 (10), 4462-4475, 2016
2162016
Identification of farnesoid X receptor β as a novel mammalian nuclear receptor sensing lanosterol
K Otte, H Kranz, I Kober, P Thompson, M Hoefer, B Haubold, B Remmel, ...
Molecular and cellular biology 23 (3), 864-872, 2003
2022003
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition
AF Hohmann, LJ Martin, JL Minder, JS Roe, J Shi, S Steurer, G Bader, ...
Nature chemical biology 12 (9), 672-679, 2016
1732016
Chemically induced degradation of the oncogenic transcription factor BCL6
N Kerres, S Steurer, S Schlager, G Bader, H Berger, M Caligiuri, C Dank, ...
Cell reports 20 (12), 2860-2875, 2017
1662017
Automated yeast two-hybrid screening for nuclear receptor-interacting proteins
M Albers, H Kranz, I Kober, C Kaiser, M Klink, J Suckow, R Kern, M Koegl
Molecular & Cellular Proteomics 4 (2), 205-213, 2005
1622005
Improving yeast two-hybrid screening systems
M Koegl, P Uetz
Briefings in Functional Genomics and Proteomics 6 (4), 302-312, 2007
1422007
Highly selective PTK2 proteolysis targeting chimeras to probe focal adhesion kinase scaffolding functions
J Popow, H Arnhof, G Bader, H Berger, A Ciulli, D Covini, C Dank, ...
Journal of Medicinal Chemistry 62 (5), 2508-2520, 2019
1262019
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