Matrix metalloproteinase activity assays: Importance of zymography K Kupai, G Szucs, S Cseh, I Hajdu, C Csonka, T Csont, P Ferdinandy Journal of pharmacological and toxicological methods 61 (2), 205-209, 2010 | 227 | 2010 |
Matrix metalloproteinase inhibitors: a critical appraisal of design principles and proposed therapeutic utility G Dormán, S Cseh, I Hajdú, L Barna, D Kónya, K Kupai, L Kovács, ... Drugs 70, 949-964, 2010 | 223 | 2010 |
A better enzyme to cope with cold: comparative flexibility studies on psychrotrophic, mesophilic, and thermophilic IPMDHS A Svingor, J Kardos, I Hajdú, A Nemeth, P Zavodszky Journal of Biological Chemistry 276 (30), 28121-28125, 2001 | 85 | 2001 |
Placental galectins are key players in regulating the maternal adaptive immune response A Balogh, E Toth, R Romero, K Parej, D Csala, NL Szenasi, I Hajdu, ... Frontiers in immunology 10, 1240, 2019 | 63 | 2019 |
Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited I Hajdú, J Kardos, B Major, G Fabó, Z Lőrincz, S Cseh, G Dormán Bioorganic & medicinal chemistry letters 28 (18), 3113-3118, 2018 | 48 | 2018 |
Substrate-assisted movement of the catalytic Lys 215 during domain closure: site-directed mutagenesis studies of human 3-phosphoglycerate kinase B Flachner, A Varga, J Szabó, L Barna, I Hajdú, G Gyimesi, P Závodszky, ... Biochemistry 44 (51), 16853-16865, 2005 | 33 | 2005 |
Target identification and polypharmacology of nutraceuticals G Dormán, B Flachner, I Hajdú, C András Nutraceuticals, 315-343, 2021 | 32 | 2021 |
Structural evidence for non-canonical binding of Ca2+ to a canonical EF-hand of a conventional myosin JÉ Debreczeni, L Farkas, V Harmat, C Hetényi, I Hajdú, P Závodszky, ... Journal of Biological Chemistry 280 (50), 41458-41464, 2005 | 27 | 2005 |
Combination of 2D/3D ligand-based similarity search in rapid virtual screening from multimillion compound repositories. Selection and biological evaluation of potential PDE4 … K Dobi, I Hajdú, B Flachner, G Fabó, M Szaszkó, M Bognár, C Magyar, ... Molecules 19 (6), 7008-7039, 2014 | 26 | 2014 |
Design, selection, and evaluation of a general kinase‐focused library H Decornez, A Gulyás‐Forró, Á Papp, M Szabó, G Sármay, I Hajdú, ... ChemMedChem 4 (8), 1273-1278, 2009 | 20 | 2009 |
Combining 2D and 3D in silico methods for rapid selection of potential PDE5 inhibitors from multimillion compounds’ repositories: biological evaluation T Tömöri, I Hajdú, L Barna, Z Lőrincz, S Cseh, G Dormán Molecular diversity 16, 59-72, 2012 | 18 | 2012 |
Rates of unfolding, rather than refolding, determine thermal stabilities of thermophilic, mesophilic, and psychrotrophic 3-isopropylmalate dehydrogenases É Gráczer, A Varga, I Hajdú, B Melnik, A Szilágyi, G Semisotnov, ... Biochemistry 46 (41), 11536-11549, 2007 | 18 | 2007 |
A link between hinge-bending domain motions and the temperature dependence of catalysis in 3-isopropylmalate dehydrogenase I Hajdú, A Szilágyi, J Kardos, P Závodszky Biophysical journal 96 (12), 5003-5012, 2009 | 16 | 2009 |
Development of matrix metalloproteinase-2 inhibitors for cardioprotection P Bencsik, K Kupai, A Görbe, É Kenyeres, ZV Varga, J Pálóczi, R Gáspár, ... Frontiers in Pharmacology 9, 296, 2018 | 15 | 2018 |
Identification of potential glutaminyl cyclase inhibitors from lead-like libraries by in silico and in vitro fragment-based screening M Szaszkó, I Hajdú, B Flachner, K Dobi, C Magyar, I Simon, Z Lőrincz, ... Molecular diversity 21 (1), 175-186, 2017 | 14 | 2017 |
Rapid identification of potential drug candidates from multi-million compounds’ repositories. combination of 2D similarity search with 3D ligand/structure based methods and in … K Szilágyi, B Flachner, I Hajdú, M Szaszkó, K Dobi, Z Lőrincz, S Cseh, ... Molecules 26 (18), 5593, 2021 | 12 | 2021 |
Design and selection of novel C1s inhibitors by in silico and in vitro approaches K Szilágyi, I Hajdú, B Flachner, Z Lőrincz, J Balczer, P Gál, P Závodszky, ... Molecules 24 (20), 3641, 2019 | 12 | 2019 |
Evolution of the concept of conformational dynamics of enzyme functions over half of a century: A personal view P Závodszky, I Hajdú Biopolymers 99 (4), 263-269, 2013 | 12 | 2013 |
Adjustment of conformational flexibility of glyceraldehyde-3-phosphate dehydrogenase as a means of thermal adaptation and allosteric regulation I Hajdú, C Bőthe, A Szilágyi, J Kardos, P Gál, P Závodszky European Biophysics Journal 37, 1139-1144, 2008 | 12 | 2008 |
Dual inhibitors of AChE and BACE-1 for reducing Aβ in Alzheimer’s disease: from in silico to in vivo N Stern, A Gacs, E Tátrai, B Flachner, I Hajdú, K Dobi, I Bágyi, G Dormán, ... International Journal of Molecular Sciences 23 (21), 13098, 2022 | 11 | 2022 |