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Sigrid Roberts
Sigrid Roberts
Pacific University Oregon School of Pharmacy
在 pacificu.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Arginase plays a pivotal role in polyamine precursor metabolism in Leishmania: characterization of gene deletion mutants
SC Roberts, MJ Tancer, MR Polinsky, KM Gibson, O Heby, B Ullman
Journal of Biological Chemistry 279 (22), 23668-23678, 2004
2032004
Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form.
R Ramamoorthy, JE Donelson, KE Paetz, M Maybodi, SC Roberts, ...
Journal of Biological Chemistry 267 (3), 1888-1895, 1992
1471992
An effect of parasite-encoded arginase on the outcome of murine cutaneous leishmaniasis
U Gaur, SC Roberts, RP Dalvi, I Corraliza, B Ullman, ME Wilson
The Journal of Immunology 179 (12), 8446-8453, 2007
1442007
Ornithine decarboxylase gene deletion mutants of Leishmania donovani
Y Jiang, SC Roberts, A Jardim, NS Carter, S Shih, M Ariyanayagam, ...
Journal of Biological Chemistry 274 (6), 3781-3788, 1999
1321999
Polyamine biosynthetic enzymes as drug targets in parasitic protozoa
O Heby, SC Roberts, B Ullman
Biochemical Society Transactions 31 (2), 415-419, 2003
1262003
Genetic analysis of spermidine synthase from Leishmania donovani
SC Roberts, Y Jiang, A Jardim, NS Carter, O Heby, B Ullman
Molecular and biochemical parasitology 115 (2), 217-226, 2001
1162001
S-Adenosylmethionine Decarboxylase fromLeishmania donovani: MOLECULAR, GENETIC, AND BIOCHEMICAL CHARACTERIZATION OF NULL MUTANTS AND OVERPRODUCERS
SC Roberts, J Scott, JE Gasteier, Y Jiang, B Brooks, A Jardim, NS Carter, ...
Journal of Biological Chemistry 277 (8), 5902-5909, 2002
1032002
Leishmania donovani Ornithine Decarboxylase Is Indispensable for Parasite Survival in the Mammalian Host
JM Boitz, PA Yates, C Kline, U Gaur, ME Wilson, B Ullman, SC Roberts
Infection and immunity 77 (2), 756-763, 2009
922009
Arginase is essential for survival of Leishmania donovani promastigotes but not intracellular amastigotes
JM Boitz, CA Gilroy, TD Olenyik, D Paradis, J Perdeh, K Dearman, ...
Infection and immunity 85 (1), 10.1128/iai. 00554-16, 2017
892017
Arginine homeostasis and transport in the human pathogen Leishmania donovani
I Darlyuk, A Goldman, SC Roberts, B Ullman, D Rentsch, D Zilberstein
Journal of biological chemistry 284 (30), 19800-19807, 2009
892009
Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections
EL D’Antonio, B Ullman, SC Roberts, UG Dixit, ME Wilson, Y Hai, ...
Archives of biochemistry and biophysics 535 (2), 163-176, 2013
882013
Learning bridge: curricular integration of didactic and experiential education
R Karimi, CS Arendt, P Cawley, AV Buhler, F Elbarbry, SC Roberts
American journal of pharmaceutical education 74 (3), 48, 2010
862010
Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi
SC Roberts, KG Swihart, MW Agey, R Ramamoorthy, ME Wilson, ...
Molecular and biochemical parasitology 62 (2), 157-171, 1993
731993
Alpha-difluoromethylornithine, an irreversible inhibitor of polyamine biosynthesis, as a therapeutic strategy against hyperproliferative and infectious diseases
N LoGiudice, L Le, I Abuan, Y Leizorek, SC Roberts
Medical Sciences 6 (1), 12, 2018
692018
Spermidine synthase is required for virulence of Leishmania donovani
C Gilroy, T Olenyik, SC Roberts, B Ullman
Infection and immunity 79 (7), 2764-2769, 2011
612011
Identification and characterization of a novel deoxyhypusine synthase in Leishmania donovani
B Chawla, A Jhingran, S Singh, N Tyagi, MH Park, N Srinivasan, ...
Journal of biological chemistry 285 (1), 453-463, 2010
602010
Developmentally regulated expression of a novel 59-kDa product of the major surface protease (Msp or gp63) gene family of Leishmania chagasi
SC Roberts, ME Wilson, JE Donelson
Journal of Biological Chemistry 270 (15), 8884-8892, 1995
521995
Leishmania donovani Polyamine Biosynthetic Enzyme Overproducers as Tools To Investigate the Mode of Action of Cytotoxic Polyamine Analogs
SC Roberts, Y Jiang, J Gasteier, B Frydman, LJ Marton, O Heby, B Ullman
Antimicrobial agents and chemotherapy 51 (2), 438-445, 2007
472007
Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I
E Riley, SC Roberts, B Ullman
International journal for parasitology 41 (5), 545-552, 2011
442011
Natural Products That Target the Arginase in Leishmania Parasites Hold Therapeutic Promise
NS Carter, BD Stamper, F Elbarbry, V Nguyen, S Lopez, Y Kawasaki, ...
Microorganisms 9 (2), 267, 2021
312021
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