Mechanism of differential control of NMDA receptor activity by NR2 subunits M Gielen, BS Retchless, L Mony, JW Johnson, P Paoletti Nature 459 (7247), 703-707, 2009 | 402 | 2009 |
Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor T Boulin, M Gielen, JE Richmond, DC Williams, P Paoletti, JL Bessereau Proceedings of the National Academy of Sciences 105 (47), 18590-18595, 2008 | 225 | 2008 |
Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites D Laverty, P Thomas, M Field, OJ Andersen, MG Gold, PC Biggin, ... Nature structural & molecular biology 24 (11), 977-985, 2017 | 193 | 2017 |
The desensitization gate of inhibitory Cys-loop receptors M Gielen, P Thomas, TG Smart Nature communications 6 (1), 6829, 2015 | 149 | 2015 |
Structural rearrangements of NR1/NR2A NMDA receptors during allosteric inhibition M Gielen, A Le Goff, D Stroebel, JW Johnson, J Neyton, P Paoletti Neuron 57 (1), 80-93, 2008 | 145 | 2008 |
Benzodiazepines modulate GABAA receptors by regulating the preactivation step after GABA binding MC Gielen, MJ Lumb, TG Smart Journal of Neuroscience 32 (17), 5707-5715, 2012 | 128 | 2012 |
The dual‐gate model for pentameric ligand‐gated ion channels activation and desensitization M Gielen, PJ Corringer The Journal of Physiology 596 (10), 1873-1902, 2018 | 122 | 2018 |
The desensitization pathway of GABAA receptors, one subunit at a time M Gielen, N Barilone, PJ Corringer Nature communications 11 (1), 5369, 2020 | 26 | 2020 |
Fonctionnement des récepteurs-canaux du glutamate-Des proteines responsables de la transmission synaptique excitatrice M Gielen médecine/sciences 26 (1), 65-72, 2010 | 17* | 2010 |
Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors MS Prevost, H Bouchenaki, N Barilone, M Gielen, PJ Corringer Cellular and Molecular Life Sciences 78, 1051-1064, 2021 | 16 | 2021 |
Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation ME Wilkins, A Caley, MC Gielen, RJ Harvey, TG Smart The Journal of Physiology 594 (13), 3589-3607, 2016 | 11 | 2016 |
Illumination of a progressive allosteric mechanism mediating the glycine receptor activation S Shi, SN Lefebvre, L Peverini, AH Cerdan, P Milán Rodríguez, M Gielen, ... Nature Communications 14 (1), 795, 2023 | 10 | 2023 |
Alterations in nicotinic receptor alpha5 subunit gene differentially impact early and later stages of cocaine addiction: a translational study in transgenic rats and patients B Forget, R Icick, J Robert, C Correia, MS Prevost, M Gielen, PJ Corringer, ... Progress in Neurobiology 197, 101898, 2021 | 10 | 2021 |
An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies MS Prevost, N Barilone, G Dejean De La Batie, S Pons, G Ayme, ... Nature Communications 14 (1), 5964, 2023 | 5 | 2023 |
Conformational state-dependent regulation of GABAA receptor diffusion and subsynaptic domains Z Merlaud, X Marques, M Russeau, U Saade, M Tostain, I Moutkine, ... Iscience 25 (11), 2022 | 4 | 2022 |
Influence of the open, closed or desensitized states of the GABAA receptor on its membrane dynamics and accumulation at inhibitory synapses M Renner, Z Merlaud, X Marques, M Russeau, I Moutkine, E François, ... Conférences Jacques Monod, 2019 | | 2019 |
Mechanistic insights into allosteric modulation of NMDA receptors P Paoletti, L Mony, D Stroebel, M Gielen FUNDAMENTAL & CLINICAL PHARMACOLOGY 22, 28-28, 2008 | | 2008 |