Current and potential applications of bismuth-based drugs DM Keogan, DM Griffith Molecules 19 (9), 15258-15297, 2014 | 194 | 2014 |
Hydroxamic acids− an intriguing family of enzyme inhibitors and biomedical ligands CJ Marmion, D Griffith, KB Nolan European Journal of Inorganic Chemistry 2004 (15), 3003-3016, 2004 | 193 | 2004 |
The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum D Gaynor, DM Griffith Dalton Transactions 41 (43), 13239-13257, 2012 | 163 | 2012 |
Medicinal chemistry and biomedical applications of bismuth-based compounds and nanoparticles DM Griffith, H Li, MV Werrett, PC Andrews, H Sun Chemical Society Reviews 50 (21), 12037-12069, 2021 | 117 | 2021 |
Suberoylanilide hydroxamic acid, a potent histone deacetylase inhibitor; its X-ray crystal structure and solid state and solution studies of its Zn (II), Ni (II), Cu (II) and … DM Griffith, B Szőcs, T Keogh, KY Suponitsky, E Farkas, P Buglyó, ... Journal of Inorganic Biochemistry 105 (6), 763-769, 2011 | 89 | 2011 |
A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity D Griffith, MP Morgan, CJ Marmion Chemical communications, 6735-6737, 2009 | 82 | 2009 |
Exploiting azide–alkyne click chemistry in the synthesis, tracking and targeting of platinum anticancer complexes NJ Farrer, DM Griffith Current Opinion in Chemical Biology 55, 59-68, 2020 | 57 | 2020 |
Valuable Insight into the Anticancer Activity of the Platinum-Histone Deacetylase Inhibitor Conjugate, cis-[Pt(NH3)2malSAHA–2H)] V Brabec, DM Griffith, A Kisova, H Kostrhunova, L Zerzankova, ... Molecular pharmaceutics 9 (7), 1990-1999, 2012 | 57 | 2012 |
Ruthenium (III) dimethyl sulfoxide pyridinehydroxamic acid complexes as potential antimetastatic agents: synthesis, characterisation and in vitro pharmacological evaluation D Griffith, S Cecco, E Zangrando, A Bergamo, G Sava, CJ Marmion JBIC Journal of Biological Inorganic Chemistry 13, 511-520, 2008 | 55 | 2008 |
Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity DM Griffith, B Duff, KY Suponitsky, K Kavanagh, MP Morgan, D Egan, ... Journal of Inorganic Biochemistry 105 (6), 793-799, 2011 | 52 | 2011 |
Enzyme inhibition as a key target for the development of novel metal-based anti-cancer therapeutics D Griffith, J P Parker, C J Marmion Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2010 | 52 | 2010 |
Novel improved synthesis of HSP70 inhibitor, pifithrin-μ. in vitro synergy quantification of pifithrin-μ combined with Pt drugs in prostate and colorectal cancer cells AM McKeon, A Egan, J Chandanshive, H McMahon, DM Griffith Molecules 21 (7), 949, 2016 | 46 | 2016 |
A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity JP Parker, H Nimir, DM Griffith, B Duff, AJ Chubb, MP Brennan, ... Journal of Inorganic Biochemistry 124, 70-77, 2013 | 37 | 2013 |
Platinum (IV) oxaliplatin–peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells AM McKeon, J Noonan, M Devocelle, BM Murphy, DM Griffith Chemical Communications 53 (82), 11318-11321, 2017 | 34 | 2017 |
Monohydroxamic acids and bridging dihydroxamic acids as chelators to ruthenium (III) and as nitric oxide donors: syntheses, speciation studies and nitric oxide releasing … D Griffith, K Krot, J Comiskey, KB Nolan, CJ Marmion Dalton Transactions, 137-147, 2008 | 30 | 2008 |
Novel palladium (II) and platinum (II) complexes of biocidal benzisothiazolinone (Bit); X-ray crystal structures of co-crystallised Bit/BitO and cis-Pd (en)(Bit− 1H) 2· H2O DM Griffith, A Haughey, S Chahal, H Müller-Bunz, CJ Marmion Inorganica Chimica Acta 363 (10), 2333-2337, 2010 | 25 | 2010 |
Novel platinum pyridinehydroxamic acid complexes: Synthesis, characterisation, X-ray crystallographic study and nitric oxide related properties D Griffith, A Bergamo, S Pin, M Vadori, H Müller-Bunz, G Sava, ... Polyhedron 26 (16), 4697-4706, 2007 | 25 | 2007 |
A single microbubble formulation carrying 5-fluorouridine, Irinotecan and oxaliplatin to enable FOLFIRINOX treatment of pancreatic and colon cancer using ultrasound targeted … J Gao, KA Logan, H Nesbitt, B Callan, T McKaig, M Taylor, M Love, ... Journal of Controlled Release 338, 358-366, 2021 | 22 | 2021 |
Novel antimony (III) hydroxamic acid complexes as potential anti-leishmanial agents DM Keogan, SSC Oliveira, LS Sangenito, MH Branquinha, RD Jagoo, ... Dalton Transactions 47 (21), 7245-7255, 2018 | 19 | 2018 |
Development of a novel carboplatin like cytoplasmic trackable near infrared fluorophore conjugate via strain-promoted azide alkyne cycloaddition E Kitteringham, D Wu, S Cheung, B Twamley, DF O'Shea, DM Griffith Journal of Inorganic Biochemistry 182, 150-157, 2018 | 18 | 2018 |