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Darren Griffith
Darren Griffith
在 rcsi.ie 的电子邮件经过验证
标题
引用次数
引用次数
年份
Current and potential applications of bismuth-based drugs
DM Keogan, DM Griffith
Molecules 19 (9), 15258-15297, 2014
1942014
Hydroxamic acids− an intriguing family of enzyme inhibitors and biomedical ligands
CJ Marmion, D Griffith, KB Nolan
European Journal of Inorganic Chemistry 2004 (15), 3003-3016, 2004
1932004
The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum
D Gaynor, DM Griffith
Dalton Transactions 41 (43), 13239-13257, 2012
1632012
Medicinal chemistry and biomedical applications of bismuth-based compounds and nanoparticles
DM Griffith, H Li, MV Werrett, PC Andrews, H Sun
Chemical Society Reviews 50 (21), 12037-12069, 2021
1172021
Suberoylanilide hydroxamic acid, a potent histone deacetylase inhibitor; its X-ray crystal structure and solid state and solution studies of its Zn (II), Ni (II), Cu (II) and …
DM Griffith, B Szőcs, T Keogh, KY Suponitsky, E Farkas, P Buglyó, ...
Journal of Inorganic Biochemistry 105 (6), 763-769, 2011
892011
A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity
D Griffith, MP Morgan, CJ Marmion
Chemical communications, 6735-6737, 2009
822009
Exploiting azide–alkyne click chemistry in the synthesis, tracking and targeting of platinum anticancer complexes
NJ Farrer, DM Griffith
Current Opinion in Chemical Biology 55, 59-68, 2020
572020
Valuable Insight into the Anticancer Activity of the Platinum-Histone Deacetylase Inhibitor Conjugate, cis-[Pt(NH3)2malSAHA–2H)]
V Brabec, DM Griffith, A Kisova, H Kostrhunova, L Zerzankova, ...
Molecular pharmaceutics 9 (7), 1990-1999, 2012
572012
Ruthenium (III) dimethyl sulfoxide pyridinehydroxamic acid complexes as potential antimetastatic agents: synthesis, characterisation and in vitro pharmacological evaluation
D Griffith, S Cecco, E Zangrando, A Bergamo, G Sava, CJ Marmion
JBIC Journal of Biological Inorganic Chemistry 13, 511-520, 2008
552008
Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity
DM Griffith, B Duff, KY Suponitsky, K Kavanagh, MP Morgan, D Egan, ...
Journal of Inorganic Biochemistry 105 (6), 793-799, 2011
522011
Enzyme inhibition as a key target for the development of novel metal-based anti-cancer therapeutics
D Griffith, J P Parker, C J Marmion
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2010
522010
Novel improved synthesis of HSP70 inhibitor, pifithrin-μ. in vitro synergy quantification of pifithrin-μ combined with Pt drugs in prostate and colorectal cancer cells
AM McKeon, A Egan, J Chandanshive, H McMahon, DM Griffith
Molecules 21 (7), 949, 2016
462016
A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity
JP Parker, H Nimir, DM Griffith, B Duff, AJ Chubb, MP Brennan, ...
Journal of Inorganic Biochemistry 124, 70-77, 2013
372013
Platinum (IV) oxaliplatin–peptide conjugates targeting memHsp70+ phenotype in colorectal cancer cells
AM McKeon, J Noonan, M Devocelle, BM Murphy, DM Griffith
Chemical Communications 53 (82), 11318-11321, 2017
342017
Monohydroxamic acids and bridging dihydroxamic acids as chelators to ruthenium (III) and as nitric oxide donors: syntheses, speciation studies and nitric oxide releasing …
D Griffith, K Krot, J Comiskey, KB Nolan, CJ Marmion
Dalton Transactions, 137-147, 2008
302008
Novel palladium (II) and platinum (II) complexes of biocidal benzisothiazolinone (Bit); X-ray crystal structures of co-crystallised Bit/BitO and cis-Pd (en)(Bit− 1H) 2· H2O
DM Griffith, A Haughey, S Chahal, H Müller-Bunz, CJ Marmion
Inorganica Chimica Acta 363 (10), 2333-2337, 2010
252010
Novel platinum pyridinehydroxamic acid complexes: Synthesis, characterisation, X-ray crystallographic study and nitric oxide related properties
D Griffith, A Bergamo, S Pin, M Vadori, H Müller-Bunz, G Sava, ...
Polyhedron 26 (16), 4697-4706, 2007
252007
A single microbubble formulation carrying 5-fluorouridine, Irinotecan and oxaliplatin to enable FOLFIRINOX treatment of pancreatic and colon cancer using ultrasound targeted …
J Gao, KA Logan, H Nesbitt, B Callan, T McKaig, M Taylor, M Love, ...
Journal of Controlled Release 338, 358-366, 2021
222021
Novel antimony (III) hydroxamic acid complexes as potential anti-leishmanial agents
DM Keogan, SSC Oliveira, LS Sangenito, MH Branquinha, RD Jagoo, ...
Dalton Transactions 47 (21), 7245-7255, 2018
192018
Development of a novel carboplatin like cytoplasmic trackable near infrared fluorophore conjugate via strain-promoted azide alkyne cycloaddition
E Kitteringham, D Wu, S Cheung, B Twamley, DF O'Shea, DM Griffith
Journal of Inorganic Biochemistry 182, 150-157, 2018
182018
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