Visualizing engrafted human cancer and therapy responses in immunodeficient zebrafish C Yan, DC Brunson, Q Tang, D Do, NA Iftimia, JC Moore, MN Hayes, ... Cell 177 (7), 1903-1914. e14, 2019 | 239 | 2019 |
Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells RJ MacLeod, M Hayes, I Pacheco American Journal of Physiology-Gastrointestinal and Liver Physiology 293 (1 …, 2007 | 221 | 2007 |
ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease M Hayes, X Gao, LX Yu, N Paria, RM Henkelman, CA Wise, B Ciruna Nature communications 5 (1), 4777, 2014 | 174 | 2014 |
Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development M Hayes, M Naito, A Daulat, S Angers, B Ciruna Development 140 (8), 1807-1818, 2013 | 144 | 2013 |
Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function A Persaud, P Alberts, M Hayes, S Guettler, I Clarke, F Sicheri, P Dirks, ... The EMBO journal 30 (16), 3259-3273, 2011 | 101 | 2011 |
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish Q Tang, JC Moore, MS Ignatius, IM Tenente, MN Hayes, EG Garcia, ... Nature communications 7 (1), 10358, 2016 | 91 | 2016 |
Insights into pediatric rhabdomyosarcoma research: Challenges and goals ME Yohe, CM Heske, E Stewart, PC Adamson, N Ahmed, CR Antonescu, ... Pediatric blood & cancer 66 (10), e27869, 2019 | 76 | 2019 |
Vangl2/RhoA signaling pathway regulates stem cell self-renewal programs and growth in rhabdomyosarcoma MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ... Cell stem cell 22 (3), 414-427. e6, 2018 | 70 | 2018 |
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma IM Tenente, MN Hayes, MS Ignatius, K McCarthy, M Yohe, S Sindiri, ... Elife 6, e19214, 2017 | 69 | 2017 |
The NOTCH1/SNAIL1/MEF2C pathway regulates growth and self-renewal in embryonal rhabdomyosarcoma MS Ignatius, MN Hayes, R Lobbardi, EY Chen, KM McCarthy, P Sreenivas, ... Cell reports 19 (11), 2304-2318, 2017 | 66 | 2017 |
tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish MS Ignatius, MN Hayes, FE Moore, Q Tang, SP Garcia, PR Blackburn, ... Elife 7, e37202, 2018 | 62 | 2018 |
Depletion of plasma membrane PtdIns(4,5)P2 reveals essential roles for phosphoinositides in flagellar biogenesis HC Wei, J Rollins, L Fabian, M Hayes, G Polevoy, C Bazinet, JA Brill Journal of cell science 121 (7), 1076-1084, 2008 | 60 | 2008 |
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma Y Wei, Q Qin, C Yan, MN Hayes, SP Garcia, H Xi, D Do, AH Jin, TC Eng, ... Nature cancer 3 (8), 961-975, 2022 | 32 | 2022 |
Discovering novel oncogenic pathways and new therapies using zebrafish models of sarcoma MN Hayes, DM Langenau Methods in Cell Biology 138, 525-561, 2017 | 17 | 2017 |
In vivo imaging of cancer in zebrafish MS Ignatius, M Hayes, DM Langenau Cancer and Zebrafish: Mechanisms, Techniques, and Models, 219-237, 2016 | 9 | 2016 |
Modeling human brain tumors in flies, worms, and zebrafish: From proof of principle to novel therapeutic targets U Shahzad, MS Taccone, SA Kumar, H Okura, S Krumholtz, J Ishida, ... Neuro-oncology 23 (5), 718-731, 2021 | 6 | 2021 |
Defining function of wild-type and three patient-specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma J Chen, K Baxi, AE Lipsitt, NR Hensch, L Wang, P Sreenivas, P Modi, ... ELife 12, e68221, 2023 | 3 | 2023 |
A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and … A Weiss, C D'Amata, BJ Pearson, MN Hayes Elife 13, RP93077, 2024 | 2 | 2024 |
Wnt-Signalwege im Knochenstoffwechsel M Peterlik Osteologie 20 (03), 197-202, 2011 | 2 | 2011 |
Extracellular calcium-sensing receptor (CaSR) stimulates Wnt5a secretion which inhibits beta-catenin signaling of intestinal epithelial cells independent of the orphan receptor … I Pacheco, M Hayes, RJ Macleod Gastroenterology 132 (4), A302-A303, 2007 | 1 | 2007 |