关注
Madeline Hayes
Madeline Hayes
Hospital for Sick Children
在 sickkids.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
Visualizing engrafted human cancer and therapy responses in immunodeficient zebrafish
C Yan, DC Brunson, Q Tang, D Do, NA Iftimia, JC Moore, MN Hayes, ...
Cell 177 (7), 1903-1914. e14, 2019
2392019
Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells
RJ MacLeod, M Hayes, I Pacheco
American Journal of Physiology-Gastrointestinal and Liver Physiology 293 (1 …, 2007
2212007
ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease
M Hayes, X Gao, LX Yu, N Paria, RM Henkelman, CA Wise, B Ciruna
Nature communications 5 (1), 4777, 2014
1742014
Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development
M Hayes, M Naito, A Daulat, S Angers, B Ciruna
Development 140 (8), 1807-1818, 2013
1442013
Nedd4‐1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function
A Persaud, P Alberts, M Hayes, S Guettler, I Clarke, F Sicheri, P Dirks, ...
The EMBO journal 30 (16), 3259-3273, 2011
1012011
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish
Q Tang, JC Moore, MS Ignatius, IM Tenente, MN Hayes, EG Garcia, ...
Nature communications 7 (1), 10358, 2016
912016
Insights into pediatric rhabdomyosarcoma research: Challenges and goals
ME Yohe, CM Heske, E Stewart, PC Adamson, N Ahmed, CR Antonescu, ...
Pediatric blood & cancer 66 (10), e27869, 2019
762019
Vangl2/RhoA signaling pathway regulates stem cell self-renewal programs and growth in rhabdomyosarcoma
MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ...
Cell stem cell 22 (3), 414-427. e6, 2018
702018
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma
IM Tenente, MN Hayes, MS Ignatius, K McCarthy, M Yohe, S Sindiri, ...
Elife 6, e19214, 2017
692017
The NOTCH1/SNAIL1/MEF2C pathway regulates growth and self-renewal in embryonal rhabdomyosarcoma
MS Ignatius, MN Hayes, R Lobbardi, EY Chen, KM McCarthy, P Sreenivas, ...
Cell reports 19 (11), 2304-2318, 2017
662017
tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
MS Ignatius, MN Hayes, FE Moore, Q Tang, SP Garcia, PR Blackburn, ...
Elife 7, e37202, 2018
622018
Depletion of plasma membrane PtdIns(4,5)P2 reveals essential roles for phosphoinositides in flagellar biogenesis
HC Wei, J Rollins, L Fabian, M Hayes, G Polevoy, C Bazinet, JA Brill
Journal of cell science 121 (7), 1076-1084, 2008
602008
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma
Y Wei, Q Qin, C Yan, MN Hayes, SP Garcia, H Xi, D Do, AH Jin, TC Eng, ...
Nature cancer 3 (8), 961-975, 2022
322022
Discovering novel oncogenic pathways and new therapies using zebrafish models of sarcoma
MN Hayes, DM Langenau
Methods in Cell Biology 138, 525-561, 2017
172017
In vivo imaging of cancer in zebrafish
MS Ignatius, M Hayes, DM Langenau
Cancer and Zebrafish: Mechanisms, Techniques, and Models, 219-237, 2016
92016
Modeling human brain tumors in flies, worms, and zebrafish: From proof of principle to novel therapeutic targets
U Shahzad, MS Taccone, SA Kumar, H Okura, S Krumholtz, J Ishida, ...
Neuro-oncology 23 (5), 718-731, 2021
62021
Defining function of wild-type and three patient-specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma
J Chen, K Baxi, AE Lipsitt, NR Hensch, L Wang, P Sreenivas, P Modi, ...
ELife 12, e68221, 2023
32023
A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and …
A Weiss, C D'Amata, BJ Pearson, MN Hayes
Elife 13, RP93077, 2024
22024
Wnt-Signalwege im Knochenstoffwechsel
M Peterlik
Osteologie 20 (03), 197-202, 2011
22011
Extracellular calcium-sensing receptor (CaSR) stimulates Wnt5a secretion which inhibits beta-catenin signaling of intestinal epithelial cells independent of the orphan receptor …
I Pacheco, M Hayes, RJ Macleod
Gastroenterology 132 (4), A302-A303, 2007
12007
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