Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors VA Adalsteinsson, G Ha, SS Freeman, AD Choudhury, DG Stover, ... Nature communications 8 (1), 1324, 2017 | 795 | 2017 |
TBCRC 022: a phase II trial of neratinib and capecitabine for patients with human epidermal growth factor receptor 2–positive breast cancer and brain metastases RA Freedman, RS Gelman, CK Anders, ME Melisko, HA Parsons, ... Journal of Clinical Oncology 37 (13), 1081-1089, 2019 | 316 | 2019 |
DNA binding features of human POT1: a nonamer 5′-TAGGGTTAG-3′ minimal binding site, sequence specificity, and internal binding to multimeric sites D Loayza, H Parsons, J Donigian, K Hoke, T de Lange Journal of Biological Chemistry 279 (13), 13241-13248, 2004 | 256 | 2004 |
Association of cell-free DNA tumor fraction and somatic copy number alterations with survival in metastatic triple-negative breast cancer DG Stover, HA Parsons, G Ha, SS Freeman, WT Barry, H Guo, ... Journal of Clinical Oncology 36 (6), 543-553, 2018 | 225 | 2018 |
ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients D Chu, C Paoletti, C Gersch, DA VanDenBerg, DJ Zabransky, ... Clinical cancer research 22 (4), 993-999, 2016 | 185 | 2016 |
Circulating tumor DNA in advanced solid tumors: clinical relevance and future directions ML Cheng, E Pectasides, GJ Hanna, HA Parsons, AD Choudhury, ... CA: a cancer journal for clinicians 71 (2), 176-190, 2021 | 145 | 2021 |
Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer HA Parsons, J Rhoades, SC Reed, G Gydush, P Ram, P Exman, K Xiong, ... Clinical Cancer Research 26 (11), 2556-2564, 2020 | 134 | 2020 |
Tumor fraction in cell-free DNA as a biomarker in prostate cancer AD Choudhury, L Werner, E Francini, XX Wei, G Ha, SS Freeman, ... JCI insight 3 (21), 2018 | 113 | 2018 |
Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA PV Toro, B Erlanger, JA Beaver, RL Cochran, DA VanDenBerg, E Yakim, ... Clinical biochemistry 48 (15), 993-998, 2015 | 98 | 2015 |
HER2 missense mutations have distinct effects on oncogenic signaling and migration DJ Zabransky, CL Yankaskas, RL Cochran, HY Wong, S Croessmann, ... Proceedings of the National Academy of Sciences 112 (45), E6205-E6214, 2015 | 95 | 2015 |
Personalized medicine in the oncology clinic: implementation and outcomes of the Johns Hopkins molecular tumor board WB Dalton, PM Forde, H Kang, RM Connolly, V Stearns, CD Gocke, ... JCO precision oncology 1, 1-19, 2017 | 87 | 2017 |
Circulating tumor DNA and late recurrence in high-risk hormone receptor–positive, human epidermal growth factor receptor 2–negative breast cancer M Lipsyc-Sharf, EC de Bruin, K Santos, R McEwen, D Stetson, A Patel, ... Journal of Clinical Oncology 40 (22), 2408-2419, 2022 | 71 | 2022 |
Individualized molecular analyses guide efforts (IMAGE): a prospective study of molecular profiling of tissue and blood in metastatic triple-negative breast cancer HA Parsons, JA Beaver, A Cimino-Mathews, SM Ali, J Axilbund, D Chu, ... Clinical Cancer Research 23 (2), 379-386, 2017 | 62 | 2017 |
A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA AL Doebley, M Ko, H Liao, AE Cruikshank, K Santos, C Kikawa, JB Hiatt, ... Nature Communications 13 (1), 7475, 2022 | 45 | 2022 |
Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth G Gydush, E Nguyen, JH Bae, T Blewett, J Rhoades, SC Reed, D Shea, ... Nature Biomedical Engineering 6 (3), 257-266, 2022 | 43 | 2022 |
Circulating plasma tumor DNA HA Parsons, JA Beaver, BH Park Novel Biomarkers in the Continuum of Breast Cancer, 259-276, 2016 | 39 | 2016 |
NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability S Croessmann, HY Wong, DJ Zabransky, D Chu, J Mendonca, A Sharma, ... Proceedings of the National Academy of Sciences 112 (37), 11583-11588, 2015 | 33 | 2015 |
Response to Olaparib in a Patient with Germline BRCA2 Mutation and Breast Cancer Leptomeningeal Carcinomatosis P Exman, RM Mallery, NU Lin, HA Parsons NPJ Breast Cancer 5 (1), 46, 2019 | 28 | 2019 |
Liquid biopsy epigenomic profiling for cancer subtyping SC Baca, JH Seo, MP Davidsohn, B Fortunato, K Semaan, S Sotudian, ... Nature medicine 29 (11), 2737-2741, 2023 | 24 | 2023 |
Aiming at a tailored cure for ERBB2-positive metastatic breast cancer: a review P Tarantino, G Curigliano, HA Parsons, NU Lin, I Krop, EA Mittendorf, ... JAMA oncology 8 (4), 629-635, 2022 | 23 | 2022 |