Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data FC Bidard, DJ Peeters, T Fehm, F Nolé, R Gisbert-Criado, D Mavroudis, ... The lancet oncology 15 (4), 406-414, 2014 | 946 | 2014 |
The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper M Cristofanilli, JY Pierga, J Reuben, A Rademaker, AA Davis, DJ Peeters, ... Critical reviews in oncology/hematology 134, 39-45, 2019 | 251 | 2019 |
MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression AE Frampton, L Castellano, T Colombo, E Giovannetti, J Krell, J Jacob, ... Gastroenterology 146 (1), 268-277. e18, 2014 | 187 | 2014 |
Patient‐derived xenografts for individualized care in advanced sarcoma J Stebbing, K Paz, GK Schwartz, LH Wexler, R Maki, RE Pollock, R Morris, ... Cancer 120 (13), 2006-2015, 2014 | 180 | 2014 |
MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors LR Jiao, AE Frampton, J Jacob, L Pellegrino, J Krell, G Giamas, N Tsim, ... PloS one 7 (2), e32068, 2012 | 173 | 2012 |
Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden AE Frampton, MM Prado, E López-Jiménez, AB Fajardo-Puerta, ... Oncotarget 9 (27), 19006, 2018 | 151 | 2018 |
miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts L Pellegrino, J Stebbing, VM Braga, AE Frampton, J Jacob, L Buluwela, ... Nucleic acids research 41 (10), 5400-5412, 2013 | 135 | 2013 |
microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis AE Frampton, J Krell, NB Jamieson, TMH Gall, E Giovannetti, N Funel, ... European journal of cancer 51 (11), 1389-1404, 2015 | 128 | 2015 |
Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosis L Roca-Alonso, L Castellano, A Mills, AF Dabrowska, MB Sikkel, ... Cell death & disease 6 (5), e1754-e1754, 2015 | 128 | 2015 |
TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression S Ottaviani, J Stebbing, AE Frampton, S Zagorac, J Krell, A de Giorgio, ... Nature communications 9 (1), 1845, 2018 | 123 | 2018 |
miR‐515‐5p controls cancer cell migration through MARK 4 regulation OE Pardo, L Castellano, CE Munro, Y Hu, F Mauri, J Krell, R Lara, ... EMBO reports 17 (4), 570-584, 2016 | 115 | 2016 |
The efficacy of axillary ultrasound in the detection of nodal metastasis in breast cancer B Lee, AK Lim, J Krell, K Satchithananda, RC Coombes, JS Lewis, ... American Journal of Roentgenology 200 (3), W314-W320, 2013 | 113 | 2013 |
Reduced dissemination of circulating tumor cells with no-touch isolation surgical technique in patients with pancreatic cancer TMH Gall, J Jacob, AE Frampton, J Krell, C Kyriakides, L Castellano, ... JAMA surgery 149 (5), 482-485, 2014 | 103 | 2014 |
Growth Arrest-Specific Transcript 5 Associated snoRNA Levels Are Related to p53 Expression and DNA Damage in Colorectal Cancer J Krell, AE Frampton, R Mirnezami, V Harding, A De Giorgio, ... PloS one 9 (6), e98561, 2014 | 93 | 2014 |
Emerging roles of competing endogenous RNAs in cancer: insights from the regulation of PTEN A de Giorgio, J Krell, V Harding, J Stebbing, L Castellano Molecular and cellular biology, 2013 | 92 | 2013 |
Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation FG Pinho, AE Frampton, J Nunes, J Krell, H Alshaker, J Jacob, ... Cancer research 73 (19), 5936-5948, 2013 | 88 | 2013 |
Maximal-effort cytoreductive surgery for ovarian cancer patients with a high tumor burden: variations in practice and impact on outcome M Hall, K Savvatis, K Nixon, M Kyrgiou, K Hariharan, M Padwick, ... Annals of surgical oncology 26, 2943-2951, 2019 | 80 | 2019 |
Viable circulating tumour cell detection using multiplex RNA in situ hybridisation predicts progression-free survival in metastatic breast cancer patients RE Payne, F Wang, N Su, J Krell, A Zebrowski, E Yagüe, XJ Ma, Y Luo, ... British journal of cancer 106 (11), 1790-1797, 2012 | 79 | 2012 |
Rechallenging with anthracyclines and taxanes in metastatic breast cancer C Palmieri, J Krell, CR James, C Harper-Wynne, V Misra, S Cleator, ... Nature reviews Clinical oncology 7 (10), 561-574, 2010 | 71 | 2010 |
IDH mutations in tumorigenesis and their potential role as novel therapeutic targets D Krell, P Mulholland, AE Frampton, J Krell, J Stebbing, C Bardella Future oncology 9 (12), 1923-1935, 2013 | 70 | 2013 |