| Self-double-emulsifying drug delivery system (SDEDDS): A new way for oral delivery of drugs with high solubility and low permeability X Qi, L Wang, J Zhu, Z Hu, J Zhang International journal of pharmaceutics 409 (1-2), 245-251, 2011 | 142 | 2011 |
| Recent developments in PROTAC‐mediated protein degradation: from bench to clinic Z Hu, CM Crews ChemBioChem 23 (2), e202100270, 2022 | 133 | 2022 |
| Small-molecule inhibition of TLR8 through stabilization of its resting state S Zhang, Z Hu, H Tanji, S Jiang, N Das, J Li, K Sakaniwa, J Jin, Y Bian, ... Nature chemical biology 14 (1), 58-64, 2018 | 123 | 2018 |
| Targeted degradation of transcription factors by TRAFTACs: transcription factor targeting chimeras KTG Samarasinghe, S Jaime-Figueroa, M Burgess, DA Nalawansha, ... Cell chemical biology 28 (5), 648-661. e5, 2021 | 121 | 2021 |
| Sensing of HIV-1 by TLR8 activates human T cells and reverses latency HZ Meås, M Haug, MS Beckwith, C Louet, L Ryan, Z Hu, J Landskron, ... Nature communications 11 (1), 147, 2020 | 82 | 2020 |
| Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling SH Moen, B Ehrnström, JF Kojen, M Yurchenko, KS Beckwith, JE Afset, ... Frontiers in immunology 10, 1209, 2019 | 66 | 2019 |
| Modulation of phosphoprotein activity by phosphorylation targeting chimeras (PhosTACs) PH Chen, Z Hu, E An, I Okeke, S Zheng, X Luo, A Gong, ... ACS chemical biology 16 (12), 2808-2815, 2021 | 61 | 2021 |
| Small-molecule TLR8 antagonists via structure-based rational design Z Hu, H Tanji, S Jiang, S Zhang, K Koo, J Chan, K Sakaniwa, U Ohto, ... Cell chemical biology 25 (10), 1286-1291. e3, 2018 | 46 | 2018 |
| Targeted dephosphorylation of tau by phosphorylation targeting chimeras (PhosTACs) as a therapeutic modality Z Hu, PH Chen, W Li, T Douglas, J Hines, Y Liu, CM Crews Journal of the American Chemical Society 145 (7), 4045-4055, 2023 | 32 | 2023 |
| TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria B Ehrnström, JF Kojen, M Giambelluca, L Ryan, SH Moen, Z Hu, H Yin, ... Journal of Leukocyte Biology 107 (4), 673-683, 2020 | 15 | 2020 |
| Synthesis of withasomnine and pyrazole derivatives via intramolecular dehydrogenative cyclization, as well as biological evaluation of withasomnine-based scaffolds T Xia, Z Hu, W Ji, S Zhang, H Shi, C Liu, B Pang, G Liu, X Liao Organic Chemistry Frontiers 5 (5), 850-854, 2018 | 15 | 2018 |
| An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells W Zhou, W Li, S Wang, B Salovska, Z Hu, B Tao, Y Di, U Punyamurtula, ... Nature Communications 14 (1), 3803, 2023 | 7 | 2023 |
| Protocol for evaluation and validation of TLR8 antagonists in HEK-Blue cells via secreted embryonic alkaline phosphatase assay Z Hu, T Zhang, S Jiang, H Yin STAR protocols 3 (1), 101061, 2022 | 4 | 2022 |
| Toll-like receptor 8 (TLR8) specific antagonists and methods of making and uses thereof HH Yin, S Zhang, Z Hu US Patent 11,466,010, 2022 | 3 | 2022 |
| EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling Z Hu, PH Chen, W Li, M Krone, S Zheng, J Saarbach, IU Velasco, J Hines, ... Science Advances 10 (13), eadj7251, 2024 | 2 | 2024 |
| Toll-Like Receptor 8 (TLR8)-Specific Antagonists and Methods of Making and Uses Thereof HH Yin, S Zhang, Z Hu US Patent App. 17/962,656, 2023 | | 2023 |
| A basic phosphoproteomic-DIA workflow integrating precise quantification of phosphosites in systems biology Y Di, W Li, B Salovska, Q Ba, Z Hu, S Wang, Y Liu Biophysics Reports 9 (2), 82, 2023 | | 2023 |
| Sensing of HIV-1 by TLR8 in human CD4+ T cells M Haug, HZ Meas, MS Beckwith, C Louet, L Ryan, Z Hu, J Landskron, ... SCANDINAVIAN JOURNAL OF IMMUNOLOGY 90 (6), 2019 | | 2019 |
| Sensing of HIV-1 nucleic acids by TLR8 in human CD4+ T cells M Haug, HZ Meas, SM Beckwith, C Louet, L Ryan, Z Hu, J Landskron, ... EUROPEAN JOURNAL OF IMMUNOLOGY 49, 1053-1054, 2019 | | 2019 |
| Discovery of novel TLR8 antagonists via structure-based rational design S Jiang, S Zhang, Z Hu, H Tanji, T Shimizu, H Yin ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
