关注
Xinyuan Li
Xinyuan Li
Janssen R&D
在 its.jnj.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
X Li, P Fang, J Mai, ET Choi, H Wang, X Yang
Journal of hematology & oncology 6 (1), 1-19, 2013
8232013
IL-35 is a novel responsive anti-inflammatory cytokine—a new system of categorizing anti-inflammatory cytokines
X Li, J Mai, A Virtue, Y Yin, R Gong, X Sha, S Gutchigian, A Frisch, ...
PloS one 7 (3), e33628, 2012
2882012
Mitochondrial reactive oxygen species mediate lysophosphatidylcholine-induced endothelial cell activation
X Li, P Fang, Y Li, YM Kuo, AJ Andrews, G Nanayakkara, C Johnson, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (6), 1090-1100, 2016
1942016
A double-edged sword: uric acid and neurological disorders
P Fang, X Li, JJ Luo, H Wang, X Yang
Brain disorders & therapy 2 (2), 109, 2013
1772013
Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway
Y Yin, X Li, X Sha, H Xi, YF Li, Y Shao, J Mai, A Virtue, J Lopez-Pastrana, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (4), 804-816, 2015
1762015
Endothelial progenitor cells in atherosclerosis
F Du, J Zhou, R Gong, X Huang, M Pansuria, A Virtue, X Li, H Wang, ...
Frontiers in bioscience: a journal and virtual library 17, 2327, 2012
1712012
Inflammasomes: sensors of metabolic stresses for vascular inflammation
Y Yin, JL Pastrana, X Li, X Huang, ET Choi, M Madesh, H Wang, XF Yang
Frontiers in bioscience: a journal and virtual library 18, 638, 2013
1422013
Immune cell subset differentiation and tissue inflammation
P Fang, X Li, J Dai, L Cole, JA Camacho, Y Zhang, Y Ji, J Wang, XF Yang, ...
Journal of hematology & oncology 11 (1), 1-22, 2018
1302018
Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction-a novel mechanism for maintaining vascular function
Y Shao, Z Cheng, X Li, V Chernaya, H Wang, X Yang
Journal of hematology & oncology 7 (1), 1-14, 2014
1242014
Interleukin-35 inhibits endothelial cell activation by suppressing MAPK-AP-1 pathway
X Sha, S Meng, X Li, H Xi, M Maddaloni, DW Pascual, H Shan, X Jiang, ...
Journal of Biological Chemistry 290 (31), 19307-19318, 2015
1022015
Inhibition of caspase-1 activation in endothelial cells improves angiogenesis: a novel therapeutic potential for ischemia
J Lopez-Pastrana, LM Ferrer, YF Li, X Xiong, H Xi, R Cueto, J Nelson, ...
Journal of Biological Chemistry 290 (28), 17485-17494, 2015
922015
MicroRNA-155 deficiency leads to decreased atherosclerosis, increased white adipose tissue obesity, and non-alcoholic fatty liver disease: a novel mouse model of obesity paradox
A Virtue, C Johnson, J Lopez-Pastraña, Y Shao, H Fu, X Li, YF Li, Y Yin, ...
Journal of Biological Chemistry 292 (4), 1267-1287, 2017
882017
IL-35 (interleukin-35) suppresses endothelial cell activation by inhibiting mitochondrial reactive oxygen species-mediated site-specific acetylation of H3K14 (histone 3 lysine 14)
X Li, Y Shao, X Sha, P Fang, YM Kuo, AJ Andrews, Y Li, WY Yang, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (3), 599-609, 2018
812018
Interleukin-17A promotes aortic endothelial cell activation via transcriptionally and post-translationally activating p38 mitogen-activated protein kinase (MAPK) pathway
J Mai, G Nanayakkara, J Lopez-Pastrana, X Li, YF Li, X Wang, A Song, ...
Journal of Biological Chemistry 291 (10), 4939-4954, 2016
672016
Lysophospholipids induce innate immune transdifferentiation of endothelial cells, resulting in prolonged endothelial activation
X Li, L Wang, P Fang, Y Sun, X Jiang, H Wang, XF Yang
Journal of Biological Chemistry 293 (28), 11033-11045, 2018
652018
Lysophospholipids and their G protein-coupled receptors in atherosclerosis
YF Li, RS Li, SB Samuel, R Cueto, XY Li, H Wang, XF Yang
Frontiers in bioscience (Landmark edition) 21 (1), 70, 2016
652016
Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune …
X Li, P Fang, Y Sun, Y Shao, WY Yang, X Jiang, H Wang, X Yang
Redox biology 28, 101373, 2020
632020
Mitochondrial ROS, uncoupled from ATP synthesis, determine endothelial activation for both physiological recruitment of patrolling cells and pathological recruitment of …
X Li, P Fang, WY Yang, K Chan, M Lavallee, K Xu, T Gao, H Wang, ...
Canadian journal of physiology and pharmacology 95 (3), 247-252, 2017
632017
c-Rel is a myeloid checkpoint for cancer immunotherapy
T Li, X Li, A Zamani, W Wang, CN Lee, M Li, G Luo, E Eiler, H Sun, ...
Nature Cancer 1 (5), 507-517, 2020
582020
IL-35, as a newly proposed homeostasis-associated molecular pattern, plays three major functions including anti-inflammatory initiator, effector, and blocker in cardiovascular …
X Li, P Fang, WY Yang, H Wang, X Yang
Cytokine 122, 154076, 2019
542019
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