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Lipidomic and transcriptomic basis of lysosomal dysfunction in progranulin deficiency BM Evers, C Rodriguez-Navas, RJ Tesla, J Prange-Kiel, CR Wasser, ... Cell reports 20 (11), 2565-2574, 2017 | 125 | 2017 |
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study C Pottier, X Zhou, RB Perkerson, M Baker, GD Jenkins, DJ Serie, ... The Lancet Neurology 17 (6), 548-558, 2018 | 124 | 2018 |
Conservation of genomic imprinting at the XIST, IGF2, and GTL2 loci in the bovine SV Dindot, KC Kent, B Evers, N Loskutoff, J Womack, JA Piedrahita Mammalian genome 15, 966-974, 2004 | 119 | 2004 |
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in … C Pottier, Y Ren, RB Perkerson, M Baker, GD Jenkins, M van Blitterswijk, ... Acta neuropathologica 137, 879-899, 2019 | 101 | 2019 |
Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin LJ Engelking, BM Evers, JA Richardson, JL Goldstein, MS Brown, G Liang The Journal of clinical investigation 116 (9), 2356-2365, 2006 | 96 | 2006 |
eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer S Suresh, BB Chen, J Zhu, RJ Golden, C Lu, BM Evers, N Novaresi, ... Nature cancer 1 (5), 533-545, 2020 | 90 | 2020 |
Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window X Wang, J Wilhelm, W Li, S Li, Z Wang, G Huang, J Wang, H Tang, ... Nature communications 11 (1), 5828, 2020 | 54 | 2020 |
Epigenetic reader BRD4 (bromodomain-containing protein 4) governs nucleus-encoded mitochondrial transcriptome to regulate cardiac function SY Kim, X Zhang, GG Schiattarella, F Altamirano, TAR Ramos, KM French, ... Circulation 142 (24), 2356-2370, 2020 | 53 | 2020 |
Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin BM Evers, MS Farooqi, JM Shelton, JA Richardson, JL Goldstein, ... Journal of investigative dermatology 130 (5), 1237-1248, 2010 | 53 | 2010 |
TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity W Fan, KB Mar, L Sari, IK Gaszek, Q Cheng, BM Evers, JM Shelton, ... Cell 184 (13), 3410-3425. e17, 2021 | 48 | 2021 |
Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Y Choi, JN Lichterman, LA Coughlin, N Poulides, W Li, P Del Valle, ... Science immunology 8 (81), eabo2003, 2023 | 40 | 2023 |
The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization A Ramirez-Martinez, Y Zhang, K Chen, J Kim, BK Cenik, JR McAnally, ... Nature communications 12 (1), 690, 2021 | 25 | 2021 |
Modulation of Mutant KrasG12D-Driven Lung Tumorigenesis In Vivo by Gain or Loss of PCDH7 Function X Zhou, MS Padanad, BM Evers, B Smith, N Novaresi, S Suresh, ... Molecular Cancer Research 17 (2), 594-603, 2019 | 23 | 2019 |
Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma P Carter, U Schnell, C Chaney, B Tong, X Pan, J Ye, G Mernaugh, ... The Journal of Clinical Investigation 131 (11), 2021 | 20 | 2021 |
Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation Y Gao, K Deason, A Jain, RA Irizarry-Caro, I Dozmorov, LA Coughlin, ... The Journal of Experimental Medicine 217 (4), 2020 | 20 | 2020 |
Remote acoustic sensing as a safety mechanism during exposure of metal implants to alternating magnetic fields B Cheng, Y Chatzinoff, D Szczepanski, C Bing, S Shaikh, O Wyman, ... PLoS One 13 (5), e0197380, 2018 | 20 | 2018 |
NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load T Pohlkamp, X Xian, CH Wong, MS Durakoglugil, GC Werthmann, ... Elife 10, e72034, 2021 | 19 | 2021 |
GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease EE Chown, P Wang, X Zhao, JJ Crowder, JW Strober, MA Sullivan, Y Xue, ... Annals of Clinical and Translational Neurology 7 (11), 2186-2198, 2020 | 19 | 2020 |
Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation T Misawa, JA SoRelle, JH Choi, T Yue, K Wang, W McAlpine, J Wang, ... Science immunology 5 (43), eaaz0085, 2020 | 19 | 2020 |