Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3324 | 2010 |
A family of drug transporters: the multidrug resistance-associated proteins P Borst, R Evers, M Kool, J Wijnholds Journal of the National Cancer Institute 92 (16), 1295-1302, 2000 | 2280 | 2000 |
The multidrug resistance protein family P Borst, R Evers, M Kool, J Wijnholds Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 347-357, 1999 | 866 | 1999 |
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA. R Evers, M Kool, L van Deemter, H Janssen, J Calafat, LC Oomen, ... The Journal of clinical investigation 101 (7), 1310-1319, 1998 | 556 | 1998 |
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein J Wijnholds, R Evers, MR van Leusden, CAAM Mol, GJR Zaman, U Mayer, ... Nature medicine 3 (11), 1275-1279, 1997 | 524 | 1997 |
Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain E Bakos, R Evers, G Szakács, GE Tusnády, E Welker, K Szabó, ... Journal of Biological Chemistry 273 (48), 32167-32175, 1998 | 395 | 1998 |
Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions É Bakos, R Evers, E Sinkó, A Váradi, P Borst, B Sarkadi Molecular pharmacology 57 (4), 760-768, 2000 | 387 | 2000 |
Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. R Evers, GJ Zaman, L van Deemter, H Jansen, J Calafat, LC Oomen, ... The Journal of clinical investigation 97 (5), 1211-1218, 1996 | 329 | 1996 |
Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition K Bleasby, JC Castle, CJ Roberts, C Cheng, WJ Bailey, JF Sina, ... Xenobiotica 36 (10-11), 963-988, 2006 | 307 | 2006 |
Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione CC PAULUSMA, MA GEER, R EVERS, M HEIJN, R OTTENHOFF, ... Biochemical Journal 338 (2), 393-401, 1999 | 305 | 1999 |
Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1-and MRP2-mediated transport R Evers, M Kool, AJ Smith, L Van Deemter, M De Haas, P Borst British journal of cancer 83 (3), 366-374, 2000 | 275 | 2000 |
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export R Evers, M De Haas, R Sparidans, J Beijnen, PR Wielinga, J Lankelma, ... British journal of cancer 83 (3), 375-383, 2000 | 273 | 2000 |
Species differences in drug transporters and implications for translating preclinical findings to humans X Chu, K Bleasby, R Evers Expert opinion on drug metabolism & toxicology 9 (3), 237-252, 2013 | 271 | 2013 |
In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development KLR Brouwer, D Keppler, KA Hoffmaster, DAJ Bow, Y Cheng, Y Lai, ... Clinical Pharmacology & Therapeutics 94 (1), 95-112, 2013 | 258 | 2013 |
The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1. R ToMMASINI, R Evers, E Vogt, C Mornet, GJ Zaman, AH Schinkel, ... Proceedings of the National Academy of Sciences 93 (13), 6743-6748, 1996 | 216 | 1996 |
Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P … XY Chu, K Bleasby, J Yabut, X Cai, GH Chan, MJ Hafey, S Xu, ... Journal of Pharmacology and Experimental Therapeutics 321 (2), 673-683, 2007 | 196 | 2007 |
Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem … B Prasad, R Evers, A Gupta, CECA Hop, L Salphati, S Shukla, ... Drug Metabolism and Disposition 42 (1), 78-88, 2014 | 189 | 2014 |
The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane RJ Raggers, A Helvoort, R Evers, G Meer Journal of cell science 112 (3), 415-422, 1999 | 178 | 1999 |
Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics L Wang, B Prasad, L Salphati, X Chu, A Gupta, CECA Hop, R Evers, ... Drug Metabolism and Disposition 43 (3), 367-374, 2015 | 174 | 2015 |
Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1 R Evers, NHP Cnubben, J Wijnholds, L van Deemter, PJ van Bladeren, ... FEBS letters 419 (1), 112-116, 1997 | 174 | 1997 |