| Genetic basis of thoracic aortic aneurysms and dissections: focus on smooth muscle cell contractile dysfunction DM Milewicz, DC Guo, V Tran-Fadulu, AL Lafont, CL Papke, S Inamoto, ... Annu. Rev. Genomics Hum. Genet. 9 (1), 283-302, 2008 | 488 | 2008 |
| TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome C Boileau, DC Guo, N Hanna, ES Regalado, D Detaint, L Gong, M Varret, ... Nature genetics 44 (8), 916-921, 2012 | 397 | 2012 |
| TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections S Inamoto, CS Kwartler, AL Lafont, YY Liang, VT Fadulu, S Duraisamy, ... Cardiovascular research 88 (3), 520-529, 2010 | 155 | 2010 |
| Genetic variants promoting smooth muscle cell proliferation can result in diffuse and diverse vascular diseases: evidence for a hyperplastic vasculomyopathy DM Milewicz, CS Kwartler, CL Papke, ES Regalado, J Cao, AJ Reid Genetics in Medicine 12 (4), 196-203, 2010 | 123 | 2010 |
| Recurrent chromosome 16p13. 1 duplications are a risk factor for aortic dissections SQ Kuang, DC Guo, SK Prakash, MLN McDonald, RJ Johnson, M Wang, ... PLoS genetics 7 (6), e1002118, 2011 | 115 | 2011 |
| FOXE3 mutations predispose to thoracic aortic aneurysms and dissections SQ Kuang, O Medina-Martinez, D Guo, L Gong, ES Regalado, ... The Journal of clinical investigation 126 (3), 948-961, 2016 | 106 | 2016 |
| Rare, Nonsynonymous Variant in the Smooth Muscle-Specific Isoform of Myosin Heavy Chain, MYH11, R247C, Alters Force Generation in the Aorta and Phenotype … SQ Kuang, CS Kwartler, KL Byanova, J Pham, L Gong, SK Prakash, ... Circulation research 110 (11), 1411-1422, 2012 | 104 | 2012 |
| Aortic Remodeling After Transverse Aortic Constriction in Mice Is Attenuated With AT1 Receptor Blockade SQ Kuang, L Geng, SK Prakash, JM Cao, S Guo, C Villamizar, ... Arteriosclerosis, thrombosis, and vascular biology 33 (9), 2172-2179, 2013 | 90 | 2013 |
| Cholesterol-induced phenotypic modulation of smooth muscle cells to macrophage/fibroblast–like cells is driven by an unfolded protein response A Chattopadhyay, CS Kwartler, K Kaw, Y Li, A Kaw, J Chen, SA LeMaire, ... Arteriosclerosis, thrombosis, and vascular biology 41 (1), 302-316, 2021 | 73 | 2021 |
| Loss of smooth muscle α-actin leads to NF-κB–dependent increased sensitivity to angiotensin II in smooth muscle cells and aortic enlargement J Chen, A Peters, CL Papke, C Villamizar, LJ Ringuette, J Cao, S Wang, ... Circulation research 120 (12), 1903-1915, 2017 | 63 | 2017 |
| Ari-1 regulates myonuclear organization together with parkin and is associated with aortic aneurysms KL Tan, NA Haelterman, CS Kwartler, ES Regalado, PT Lee, ... Developmental cell 45 (2), 226-244. e8, 2018 | 58 | 2018 |
| Loss-of-function mutations in YY1AP1 lead to grange syndrome and a fibromuscular dysplasia-like vascular disease D Guo, XY Duan, ES Regalado, L Mellor-Crummey, CS Kwartler, D Kim, ... The American Journal of Human Genetics 100 (1), 21-30, 2017 | 56 | 2017 |
| Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2+/− mice J Cao, L Gong, D Guo, U Mietzsch, SQ Kuang, CS Kwartler, H Safi, ... Human molecular genetics 19 (10), 1908-1920, 2010 | 55 | 2010 |
| Overexpression of smooth muscle myosin heavy chain leads to activation of the unfolded protein response and autophagic turnover of thick filament-associated proteins in … CS Kwartler, J Chen, D Thakur, S Li, K Baskin, S Wang, ZV Wang, ... Journal of Biological Chemistry 289 (20), 14075-14088, 2014 | 50 | 2014 |
| Smooth muscle hyperplasia due to loss of smooth muscle α-actin is driven by activation of focal adhesion kinase, altered p53 localization and increased levels of platelet … CL Papke, J Cao, CS Kwartler, C Villamizar, KL Byanova, SM Lim, ... Human molecular genetics 22 (15), 3123-3137, 2013 | 44 | 2013 |
| National Heart L, Blood Institute Go Exome Sequencing P, Jondeau G, Milewicz DM. TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild … C Boileau, DC Guo, N Hanna, ES Regalado, D Detaint, L Gong, M Varret, ... Nat Genet 44 (8), 916-21, 2012 | 38* | 2012 |
| Variants of unknown significance in genes associated with heritable thoracic aortic disease can be low penetrant “risk variants” CS Kwartler, L Gong, J Chen, S Wang, R Kulmacz, X Duan, A Janda, ... The American Journal of Human Genetics 103 (1), 138-143, 2018 | 37 | 2018 |
| Vascular smooth muscle cell isolation and culture from mouse aorta CS Kwartler, P Zhou, SQ Kuang, XY Duan, L Gong, DM Milewicz Bio-protocol 6 (23), e2045-e2045, 2016 | 20 | 2016 |
| Stromal β-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor KA Drake, CP Chaney, A Das, P Roy, CS Kwartler, D Rakheja, TJ Carroll Development 147 (21), dev189597, 2020 | 19 | 2020 |
| Reversal of aortic enlargement induced by increased biomechanical forces requires AT1R inhibition in conjunction with AT2R activation Z Zhou, AM Peters, S Wang, A Janda, J Chen, P Zhou, E Arthur, ... Arteriosclerosis, thrombosis, and vascular biology 39 (3), 459-466, 2019 | 17 | 2019 |
