Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer S Varambally, Q Cao, RS Mani, S Shankar, X Wang, B Ateeq, B Laxman, ... science 322 (5908), 1695-1699, 2008 | 1355 | 2008 |
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma N Palanisamy, B Ateeq, S Kalyana-Sundaram, D Pflueger, ... Nature medicine 16 (7), 793-798, 2010 | 554 | 2010 |
Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer V Kumar, K Ramnarayanan, R Sundar, N Padmanabhan, S Srivastava, ... Cancer discovery 12 (3), 670-691, 2022 | 224 | 2022 |
Genomic Loss of miR-486 Regulates Tumor Progression and the OLFM4 Antiapoptotic Factor in Gastric Cancer HK Oh, ALK Tan, K Das, CH Ooi, NT Deng, IBH Tan, E Beillard, J Lee, ... Clinical cancer research 17 (9), 2657-2667, 2011 | 217 | 2011 |
Activation of transforming growth factor beta 1 signaling in gastric cancer-associated fibroblasts increases their motility, via expression of rhomboid 5 homolog 2, and ability … T Ishimoto, K Miyake, T Nandi, M Yashiro, N Onishi, KK Huang, SJ Lin, ... Gastroenterology 153 (1), 191-204. e16, 2017 | 203 | 2017 |
Genomic and epigenomic profiling of high-risk intestinal metaplasia reveals molecular determinants of progression to gastric cancer KK Huang, K Ramnarayanan, F Zhu, S Srivastava, C Xu, ALK Tan, M Lee, ... Cancer cell 33 (1), 137-150. e5, 2018 | 200 | 2018 |
RCP is a human breast cancer–promoting gene with Ras-activating function J Zhang, X Liu, A Datta, K Govindarajan, WL Tam, J Han, J George, ... The Journal of clinical investigation 119 (8), 2171-2183, 2009 | 146 | 2009 |
Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma H Huynh, PKH Chow, N Palanisamy, M Salto-Tellez, BC Goh, CK Lee, ... Journal of hepatology 49 (1), 52-60, 2008 | 92 | 2008 |
Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates BMQ Sim, N Chantratita, WF Ooi, T Nandi, R Tewhey, V Wuthiekanun, ... Genome biology 11, 1-17, 2010 | 90 | 2010 |
CD44-SLC1A2 gene fusions in gastric cancer J Tao, NT Deng, K Ramnarayanan, B Huang, HK Oh, SH Leong, SS Lim, ... Science translational medicine 3 (77), 77ra30-77ra30, 2011 | 88 | 2011 |
Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance AL Vettore, K Ramnarayanan, G Poore, K Lim, CK Ong, KK Huang, ... Genome medicine 7, 1-15, 2015 | 87 | 2015 |
Exome-wide sequencing shows low mutation rates and identifies novel mutated genes in seminomas I Cutcutache, Y Suzuki, IB Tan, S Ramgopal, S Zhang, K Ramnarayanan, ... European urology 68 (1), 77-83, 2015 | 69 | 2015 |
Long-read transcriptome sequencing reveals abundant promoter diversity in distinct molecular subtypes of gastric cancer KK Huang, J Huang, JKL Wu, M Lee, ST Tay, V Kumar, K Ramnarayanan, ... Genome biology 22, 1-24, 2021 | 64 | 2021 |
High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer IB Tan, S Malik, K Ramnarayanan, JR McPherson, DL Ho, Y Suzuki, ... Genome biology 16, 1-16, 2015 | 52 | 2015 |
Telomere‐mediated genomic instability and the clinico‐pathological parameters in breast cancer A Poonepalli, B Banerjee, K Ramnarayanan, N Palanisamy, TC Putti, ... Genes, chromosomes and cancer 47 (12), 1098-1109, 2008 | 51 | 2008 |
Multiregion ultra‐deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer Y Suzuki, SB Ng, C Chua, WQ Leow, J Chng, SY Liu, K Ramnarayanan, ... Molecular oncology 11 (2), 124-139, 2017 | 46 | 2017 |
Exome sequencing reveals recurrent REV3L mutations in cisplatin-resistant squamous cell carcinoma of head and neck KK Huang, KW Jang, S Kim, HS Kim, SM Kim, HJ Kwon, HR Kim, HJ Yun, ... Scientific reports 6 (1), 19552, 2016 | 39 | 2016 |
Epigenetic promoter alterations in GI tumour immune-editing and resistance to immune checkpoint inhibition R Sundar, KK Huang, V Kumar, K Ramnarayanan, D Demircioglu, Z Her, ... Gut 71 (7), 1277-1288, 2022 | 27 | 2022 |
Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities SWT Ho, T Sheng, M Xing, WF Ooi, C Xu, R Sundar, KK Huang, Z Li, ... Gut 72 (2), 226-241, 2023 | 17 | 2023 |
Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression KK Huang, H Ma, RHH Chong, T Uchihara, BSX Lian, F Zhu, T Sheng, ... Cancer Cell 41 (12), 2019-2037. e8, 2023 | 13 | 2023 |