Type I and type II Fc receptors regulate innate and adaptive immunity A Pincetic, S Bournazos, DJ DiLillo, J Maamary, TT Wang, R Dahan, ... Nature immunology 15 (8), 707-716, 2014 | 578 | 2014 |
Reprogramming tumor-associated macrophages by antibody targeting inhibits cancer progression and metastasis AM Georgoudaki, KE Prokopec, VF Boura, E Hellqvist, S Sohn, J Östling, ... Cell reports 15 (9), 2000-2011, 2016 | 571 | 2016 |
FcγRs modulate the anti-tumor activity of antibodies targeting the PD-1/PD-L1 axis R Dahan, E Sega, J Engelhardt, M Selby, AJ Korman, JV Ravetch Cancer cell 28 (3), 285-295, 2015 | 555 | 2015 |
Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ... Immunity 46 (4), 577-586, 2017 | 450 | 2017 |
Signaling by antibodies: recent progress S Bournazos, TT Wang, R Dahan, J Maamary, JV Ravetch Annual review of immunology 35 (1), 285-311, 2017 | 225 | 2017 |
Therapeutic activity of agonistic, human anti-CD40 monoclonal antibodies requires selective FcγR engagement R Dahan, BC Barnhart, F Li, AP Yamniuk, AJ Korman, JV Ravetch Cancer cell 29 (6), 820-831, 2016 | 184 | 2016 |
Single-cell genomic approaches for developing the next generation of immunotherapies I Yofe, R Dahan, I Amit Nature medicine 26 (2), 171-177, 2020 | 105 | 2020 |
T-cell-receptor-like antibodies–generation, function and applications R Dahan, Y Reiter Expert reviews in molecular medicine 14, e6, 2012 | 100 | 2012 |
Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity DA Knorr, R Dahan, JV Ravetch Proceedings of the National Academy of Sciences 115 (43), 11048-11053, 2018 | 85 | 2018 |
Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis A Watson, H Li, B Ma, R Weiss, D Bendayan, L Abramovitz, ... Nature Communications 12 (1), 602, 2021 | 70 | 2021 |
A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 … S Sinha, S Subramanian, TM Proctor, LJ Kaler, M Grafe, R Dahan, J Huan, ... Journal of Neuroscience 27 (46), 12531-12539, 2007 | 62 | 2007 |
Anti-SARS-CoV-2 antibodies elicited by COVID-19 mRNA vaccine exhibit a unique glycosylation pattern I Farkash, T Feferman, N Cohen-Saban, Y Avraham, D Morgenstern, ... Cell reports 37 (11), 110114, 2021 | 60 | 2021 |
HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis R Meza-Romero, G Benedek, X Yu, JL Mooney, R Dahan, N Duvshani, ... The Journal of Immunology 192 (9), 4164-4173, 2014 | 55 | 2014 |
BCR affinity differentially regulates colonization of the subepithelial dome and infiltration into germinal centers within Peyer’s patches A Biram, A Strömberg, E Winter, L Stoler-Barak, R Salomon, Y Addadi, ... Nature immunology 20 (4), 482-492, 2019 | 53 | 2019 |
A novel regulatory pathway for autoimmune disease: binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T … AA Vandenbark, R Meza-Romero, G Benedek, S Andrew, J Huan, ... Journal of autoimmunity 40, 96-110, 2013 | 45 | 2013 |
Next generation CD40 agonistic antibodies for cancer immunotherapy R Salomon, R Dahan Frontiers in immunology 13, 940674, 2022 | 43 | 2022 |
Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting R Salomon, H Rotem, Y Katzenelenbogen, A Weiner, N Cohen Saban, ... Nature cancer 3 (3), 287-302, 2022 | 38 | 2022 |
Bispecific dendritic-T cell engager potentiates anti-tumor immunity YS Itai, O Barboy, R Salomon, A Bercovich, K Xie, E Winter, T Shami, ... Cell 187 (2), 375-389. e18, 2024 | 33 | 2024 |
Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy N Cohen Saban, A Yalin, T Landsberger, R Salomon, A Alva, T Feferman, ... Science immunology 8 (81), eadd8005, 2023 | 26 | 2023 |
Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope R Dahan, JA Gebe, A Preisinger, EA James, M Tendler, GT Nepom, ... Journal of autoimmunity 47, 83-93, 2013 | 21 | 2013 |