Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1 P Singhmar, XJ Huo, N Eijkelkamp, SR Berciano, F Baameur, FC Mei, ... Proceedings of the National Academy of Sciences 113 (11), 3036-3041, 2016 | 127 | 2016 |
Mutations in WDR62, encoding a centrosomal and nuclear protein, in Indian primary microcephaly families with cortical malformations V Bhat, SC Girimaji, G Mohan, HR Arvinda, P Singhmar, MR Duvvari, ... Clinical genetics 80 (6), 532-540, 2011 | 89 | 2011 |
The fibroblast-derived protein PI16 controls neuropathic pain P Singhmar, RTP Trinh, J Ma, XJ Huo, B Peng, CJ Heijnen, A Kavelaars Proceedings of the National Academy of Sciences 117 (10), 5463-5471, 2020 | 55 | 2020 |
Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy P Singhmar, XJ Huo, Y Li, PM Dougherty, F Mei, X Cheng, CJ Heijnen, ... Pain 159 (5), 884-893, 2018 | 49 | 2018 |
Angelman syndrome protein UBE3A interacts with primary microcephaly protein ASPM, localizes to centrosomes and regulates chromosome segregation P Singhmar, A Kumar PloS one 6 (5), e20397, 2011 | 40 | 2011 |
TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain MM Kasembeli, P Singhmar, J Ma, J Edralin, Y Tang, C Adams III, ... Biochemical pharmacology 192, 114688, 2021 | 26 | 2021 |
Bexarotene normalizes chemotherapy-induced myelin decompaction and reverses cognitive and sensorimotor deficits in mice ACA Chiang, AV Seua, P Singhmar, LD Arroyo, R Mahalingam, J Hu, ... Acta Neuropathologica Communications 8, 1-15, 2020 | 22 | 2020 |
Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS V Bajaj, P Singhmar, A Kumar Gene 424 (1-2), 40-47, 2008 | 17 | 2008 |
Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1 F Baameur, P Singhmar, Y Zhou, JF Hancock, X Cheng, CJ Heijnen, ... Scientific reports 6 (1), 36370, 2016 | 16 | 2016 |
Sensory neuron cAMP signaling in chronic pain N Eijkelkamp, P Singhmar, CJ Heijnen, A Kavelaars Cyclic Nucleotide Signaling 13, 113, 2015 | 5 | 2015 |
Corrigendum to “TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain”[Biochem … MM Kasembeli, P Singhmar, J Ma, J Edralin, Y Tang, C Adams III, ... Biochemical pharmacology 195, 114860, 2022 | 1 | 2022 |
PI16 is a non-neuronal regulator of neuropathic pain P Singhmar, RTP Trinh, J Ma, XJ Huo, B Peng, CJ Heijnen, A Kavelaars bioRxiv, 696542, 2019 | 1 | 2019 |
Phosphorylation of Epac1 by GRK2 inhibits Epac1‐Rap1 signaling and prevents chronic pain (802.7) P Singhmar, XJ Huo, S Berciano, D Hawke, X Cheng, F Mei, F Mayor, ... The FASEB Journal 28, 802.7, 2014 | 1 | 2014 |
TTI-101: A competitive inhibitor of STAT3 that spares oxidative phosphorylation and reverses mechanical allodynia in mouse models of neuropathic pain (vol 192, 114688, 2021) MM Kasembeli, P Singhmar, J Ma, J Edralin, Y Tang, C Adams III, ... BIOCHEMICAL PHARMACOLOGY 195, 2022 | | 2022 |
Critical Role of GRK2 in the Prevention of Chronic Pain F Baameur, P Singhmar, CJ Heijnen, A Kavelaars G Protein-Coupled Receptor Kinases, 187-213, 2016 | | 2016 |
63. GRK2 phosphorylates Epac1 to inhibit signaling and prevent chronic inflammatory pain P Singhmar, H Wang, N Eijkelkamp, X Huo, C Murga, X Cheng, F Major, ... Abstracts from the 21st Annual PNIRS Meeting 40, e1-e52, 2014 | | 2014 |
Functional Analysis Of Primary Microcephaly Gene Product ASPM P Singhmar | | 2013 |