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Konstantin Helmsauer
Konstantin Helmsauer
Department of Pediatric Oncology/Hematology, Charité Universitätsmedizin Berlin
在 charite.de 的电子邮件经过验证
标题
引用次数
引用次数
年份
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
RP Koche*, E Rodriguez-Fos*, K Helmsauer*, M Burkert, IC MacArthur, ...
Nature genetics 52 (1), 29-34, 2020
2932020
EcDNA hubs drive cooperative intermolecular oncogene expression
KL Hung*, KE Yost*, L Xie*, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ...
Nature 600, 731-736, 2021
2082021
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma
K Helmsauer*, ME Valieva*, S Ali*, RC González, R Schöpflin, ...
Nature communications 11 (1), 1-12, 2020
1642020
Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells
R Chamorro González, T Conrad, MC Stöber, R Xu, M Giurgiu, ...
Nature Genetics 55 (5), 880-890, 2023
412023
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma
H Dorado García, F Pusch, Y Bei, J von Stebut, G Ibáñez, K Guillan, ...
Nature Communications 13 (1), 4297, 2022
172022
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN
S Fuchs, C Danßmann, F Klironomos, A Winkler, J Fallmann, ...
Nature Communications 14 (1), 3936, 2023
82023
Enhancer hijacking determines intra-and extrachromosomal circular MYCN amplicon architecture in neuroblastoma
K Helmsauer, M Valieva, S Ali, R Chamorro González, R Schöpflin, ...
bioRxiv, 2019
52019
Decoil: Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data
M Giurgiu, N Wittstruck, E Rodriguez-Fos, RC Gonzalez, L Brückner, ...
International Conference on Research in Computational Molecular Biology, 406-411, 2024
42024
Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data using Decoil
M Giurgiu, N Wittstruck, E Rodriguez-Fos, RC González, L Brückner, ...
Genome research 34 (9), 1355-1364, 2024
32024
Exploiting a PAX3-FOXO1-induced synthetic lethal ATR dependency for rhabdomyosarcoma therapy
HD García, Y Bei, J von Stebut, G Ibáñez, K Imami, D Gürgen, J Rolff, ...
bioRxiv, 2020.12. 04.411413, 2020
12020
Reconstructing extrachromosomal DNA structural heterogeneity from long-read sequencing data using Decoil
K Helmsauer, A Hartebrodt, P Euskirchen, RP Koche
2024
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy
L Grunewald, L Andersch, K Helmsauer, S Schwiebert, A Klaus, ...
bioRxiv, 2024.01. 27.576592, 2024
2024
MYCN amplification in neuroblastoma: sequence, chromatin landscape, and genome remodeling
K Helmsauer
2023
Dissecting intercellular extrachromosomal circular DNA heterogeneity in single cancer cells with scEC&T-seq
RC Gonzalez, T Conrad, R Xu, M Giurgiu, M Cwikla, K Kasack, ...
Cancer Research 82 (12_Supplement), 1693-1693, 2022
2022
Enhancer hijacking on the MYCN amplicon in neuroblastoma
K Helmsauer, M Valieva, S Ali, RC Gonzalez, R Schöpflin, JH Schulte, ...
Klinische Pädiatrie 232 (03), 2020
2020
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