| Broad phenotype of cysteine-altering NOTCH3 variants in UK Biobank: CADASIL to nonpenetrance JW Rutten, RJ Hack, M Duering, G Gravesteijn, JG Dauwerse, M Overzier, ... Neurology 95 (13), e1835-e1843, 2020 | 73 | 2020 |
| Cysteine-Altering NOTCH3 Variants Are a Risk Factor for Stroke in the Elderly Population RJ Hack, JW Rutten, TN Person, J Li, A Khan, CJ Griessenauer, ... Stroke 51 (12), 3562-3569, 2020 | 41 | 2020 |
| NOTCH3 variant position is associated with NOTCH3 aggregation load in CADASIL vasculature G Gravesteijn, RJ Hack, AA Mulder, MN Cerfontaine, R van Doorn, ... Neuropathology and Applied Neurobiology 48 (1), e12751, 2022 | 29 | 2022 |
| Effect of NOTCH3 EGFr Group, Sex, and Cardiovascular Risk Factors on CADASIL Clinical and Neuroimaging Outcomes RJ Hack, MN Cerfontaine, G Gravesteijn, S Tap, A Hafkemeijer, ... Stroke 53 (10), 3133-3144, 2022 | 23 | 2022 |
| Cadasil RJ Hack, J Rutten, LO SAJ | 23 | 2019 |
| Three-tiered EGFr domain risk stratification for individualized NOTCH3-small vessel disease prediction RJ Hack, G Gravesteijn, MN Cerfontaine, MA Santcroos, L Gatti, ... Brain 146 (7), 2913-2927, 2023 | 20 | 2023 |
| Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Family Members With a Pathogenic NOTCH3 Variant Can Have a … RJ Hack, G Gravesteijn, MN Cerfontaine, IM Hegeman, AA Mulder, ... Stroke 53 (6), 1964-1974, 2022 | 18 | 2022 |
| Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial A Kopczak, MS Stringer, H van den Brink, D Kerkhofs, GW Blair, ... The Lancet Neurology 22 (11), 991-1004, 2023 | 17 | 2023 |
| Eighteen-year disease progression and survival in CADASIL G Gravesteijn, RJ Hack, AM van Opstal, BJ van Eijsden, HAM Middelkoop, ... Journal of Stroke 23 (1), 132-134, 2021 | 12 | 2021 |
| GeneReviews® RJ Hack, J Rutten, SAJL Oberstein, MP Adam, HH Ardinger, RA Pagon, ... University of Washington, 1993 | 7 | 1993 |
| CADASIL. 2000 Mar 15 [Updated 2019 Mar 14] RJ Hack, J Rutten, SAJ Lesnik Oberstein GeneReviews®[Internet]. Seattle (WA): University of Washington, Seattle 2020, 1993 | 6 | 1993 |
| Association of NOTCH3 Variant Risk Category With 2-Year Clinical and Radiologic Small Vessel Disease Progression in Patients With CADASIL MN Cerfontaine, RJ Hack, B Gesierich, M Duering, MNW Witjes-Ané, ... Neurology 102 (10), e209310, 2024 | 1 | 2024 |
| Unra eling The Broad NOTCH3-associated Small Vessel Disease Spectrum: from CADASIL to nonpenetrance R Hack Leiden University, 2024 | | 2024 |
| NOTCH3 VARIANT POSITION IS ASSOCIATED WITH VASCULAR NOTCH3 AGGREGATION LOAD IN CADASIL PATIENTS G Gravesteijn, RJ Hack, AA Mulder, MN Cerfontaine, R van Doorn, ... Cerebral Circulation-Cognition and Behavior 6, 100107, 2024 | | 2024 |
| What's in a Domain? The Role of NOTCH3 EGFr Domains in CADASIL Disease Severity R Hack, J Rutten, SAJ Lesnik Oberstein Neurology 99 (5), 179-180, 2022 | | 2022 |
| Long-term disease progression in CADASIL: an 18-year follow-up study G Gravesteijn, RJ Hack, AM van Opstal, BJ van Eijsden, M Overzier, ... Preparing for CADASIL therapy 44, 79, 1998 | | 1998 |
| Disease Severity Staging System for NOTCH3-Associated Small Vessel Disease, Including CADASIL G Gravesteijn, JW Rutten, MN Cerfontaine, RJ Hack, YC Liao, AA Jolly, ... JAMA neurology, 0 | | |
