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M. Lienhard Schmitz
M. Lienhard Schmitz
Professor of Biochemistry, University of Giessen
在 biochemie.med.uni-giessen.de 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B.
ML Schmitz, PA Baeuerle
The EMBO journal 10 (12), 3805-3817, 1991
10311991
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
WV Berghe, S Plaisance, E Boone, K De Bosscher, ML Schmitz, W Fiers, ...
Journal of Biological Chemistry 273 (6), 3285-3290, 1998
8231998
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
TG Hofmann, A Möller, H Sirma, H Zentgraf, Y Taya, W Dröge, H Will, ...
Nature cell biology 4 (1), 1-10, 2002
7262002
The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex
SP Hehner, TG Hofmann, W Dröge, ML Schmitz
The Journal of Immunology 163 (10), 5617-5623, 1999
5241999
Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of IκB-α and IκB-β
SP Hehner, M Heinrich, PM Bork, M Vogt, F Ratter, V Lehmann, ...
Journal of Biological Chemistry 273 (3), 1288-1297, 1998
4801998
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKϵ, TRAF …
H Buss, A Dörrie, ML Schmitz, E Hoffmann, K Resch, M Kracht
Journal of Biological Chemistry 279 (53), 55633-55643, 2004
4682004
Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation
K De Bosscher, ML Schmitz, W Vanden Berghe, S Plaisance, W Fiers, ...
Proceedings of the National Academy of Sciences 94 (25), 13504-13509, 1997
4571997
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF‐κB
PM Bork, ML Schmitz, M Kuhnt, C Escher, M Heinrich
FEBS letters 402 (1), 85-90, 1997
4241997
Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB
A Dumont, SP Hehner, TG Hofmann, M Ueffing, W DroÈge, ML Schmitz
Oncogene 18 (3), 747-757, 1999
4091999
The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB–stimulated gene transcription
S Ali, A Mohs, M Thomas, J Klare, R Ross, ML Schmitz, MU Martin
The Journal of Immunology 187 (4), 1609-1616, 2011
4072011
NF‐κB: a multifaceted transcription factor regulated at several levels
ML Schmitz, I Mattioli, H Buss, M Kracht
Chembiochem 5 (10), 1348-1358, 2004
3542004
The pro‐or anti‐apoptotic function of NF‐κB is determined by the nature of the apoptotic stimulus
B Kaltschmidt, C Kaltschmidt, TG Hofmann, SP Hehner, W Dröge, ...
European journal of biochemistry 267 (12), 3828-3835, 2000
3402000
IκB-independent control of NF-κB activity by modulatory phosphorylations
ML Schmitz, S Bacher, M Kracht
Trends in biochemical sciences 26 (3), 186-190, 2001
3242001
Phosphorylation of serine 468 by GSK-3β negatively regulates basal p65 NF-κB activity
H Buss, A Dorrie, ML Schmitz, R Frank, M Livingstone, K Resch, M Kracht
Journal of Biological Chemistry 279 (48), 49571-49574, 2004
3222004
Activation of transcription factor NF-κB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways
S Wesselborg, MKA Bauer, M Vogt, ML Schmitz, K Schulze-Osthoff
Journal of Biological Chemistry 272 (19), 12422-12429, 1997
2931997
Transient and selective NF-κB p65 serine 536 phosphorylation induced by T cell costimulation is mediated by IκB kinase β and controls the kinetics of p65 nuclear import
I Mattioli, A Sebald, C Bucher, RP Charles, H Nakano, M Kracht, ...
The Journal of Immunology 172 (10), 6336-6344, 2004
2802004
Sex reversal by loss of the C–terminal transactivation domain of human SOX9
P Südbeck, ML Schmitz, PA Baeuerle, G Scherer
Nature genetics 13 (2), 230-232, 1996
2601996
Mutational Analysis of the SOX9 Gene in Campomelic Dysplasia and Autosomal Sex Reversal: Lack of Genotype/Phenotype Correlations
J Meyer, P Südbeck, M Held, T Wagner, ML Schmitz, F Dagna Bricarelli, ...
Human molecular genetics 6 (1), 91-98, 1997
2131997
Interaction of the COOH-terminal transactivation domain of p65 NF-κB with TATA-binding protein, transcription factor IIB, and coactivators
ML Schmitz, G Stelzer, H Altmann, M Meisterernst, PA Baeuerle
Journal of Biological Chemistry 270 (13), 7219-7226, 1995
2081995
Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation.
ML Schmitz, MA dos Santos Silva, H Altmann, M Czisch, TA Holak, ...
Journal of Biological Chemistry 269 (41), 25613-25620, 1994
2081994
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