Mechanism of activation of protein kinase JAK2 by the growth hormone receptor AJ Brooks, W Dai, ML O’Mara, D Abankwa, Y Chhabra, RA Pelekanos, ... Science 344 (6185), 1249783, 2014 | 397 | 2014 |
The growth hormone receptor: mechanism of activation and clinical implications AJ Brooks, MJ Waters Nature Reviews Endocrinology 6 (9), 515-525, 2010 | 377 | 2010 |
A small region of the dengue virus-encoded RNA-dependent RNA polymerase, NS5, confers interaction with both the nuclear transport receptor importin-β and the viral helicase, NS3 M Johansson, AJ Brooks, DA Jans, SG Vasudevan Journal of General Virology 82 (4), 735-745, 2001 | 228 | 2001 |
The growth hormone receptor: mechanism of receptor activation, cell signaling, and physiological aspects F Dehkhoda, CMM Lee, J Medina, AJ Brooks Frontiers in endocrinology 9, 35, 2018 | 206 | 2018 |
The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin β1 and importin α/β-recognized nuclear localization … AJ Brooks, M Johansson, AV John, Y Xu, DA Jans, SG Vasudevan Journal of Biological Chemistry 277 (39), 36399-36407, 2002 | 168 | 2002 |
Growth hormone receptor; mechanism of action AJ Brooks, JW Wooh, KA Tunny, MJ Waters The international journal of biochemistry & cell biology 40 (10), 1984-1989, 2008 | 149 | 2008 |
JAK2 activation by growth hormone and other cytokines MJ Waters, AJ Brooks Biochemical Journal 466, 1-11, 2015 | 136 | 2015 |
Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesis BL Conway-Campbell, JW Wooh, AJ Brooks, D Gordon, RJ Brown, ... Proceedings of the National Academy of Sciences 104 (33), 13331-13336, 2007 | 121 | 2007 |
An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway SW Rowlinson, H Yoshizato, JL Barclay, AJ Brooks, SN Behncken, ... Nature cell biology 10 (6), 740-747, 2008 | 118 | 2008 |
The 37-amino-acid interdomain of dengue virus NS5 protein contains a functional NLS and inhibitory CK2 site JK Forwood, A Brooks, LJ Briggs, CY Xiao, DA Jans, SG Vasudevan Biochemical and biophysical research communications 257 (3), 731-737, 1999 | 115 | 1999 |
Innate transcriptional networks activated in bladder in response to uropathogenic Escherichia coli drive diverse biological pathways and rapid synthesis of IL-10 for defense … BL Duell, AJ Carey, CK Tan, X Cui, RI Webb, M Totsika, MA Schembri, ... The Journal of Immunology 188 (2), 781-792, 2012 | 106 | 2012 |
Role of the growth hormone–IGF-1 axis in cancer Y Chhabra, MJ Waters, AJ Brooks Expert Review of Endocrinology & Metabolism 6 (1), 71-84, 2014 | 86 | 2014 |
JAK-STAT signalling pathway in cancer AJ Brooks, T Putoczki Cancers 12 (7), 1971, 2020 | 71 | 2020 |
Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes GW Haxholm, LF Nikolajsen, JG Olsen, J Fredsted, FH Larsen, V Goffin, ... Biochemical Journal 468 (3), 495-506, 2015 | 67 | 2015 |
Tmem2 regulates embryonic Vegf signaling by controlling hyaluronic acid turnover JE De Angelis, AK Lagendijk, H Chen, A Tromp, NI Bower, KA Tunny, ... Developmental cell 40 (2), 123-136, 2017 | 65 | 2017 |
Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling MA Fernández-Rojo, M Gongora, RL Fitzsimmons, N Martel, SD Martin, ... Cell reports 4 (2), 238-247, 2013 | 57 | 2013 |
The extracellular domain of the growth hormone receptor interacts with coactivator activator to promote cell proliferation BL Conway-Campbell, AJ Brooks, PJ Robinson, M Perani, MJ Waters Molecular endocrinology 22 (9), 2190-2202, 2008 | 52 | 2008 |
A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation Y Chhabra, HY Wong, LF Nikolajsen, H Steinocher, A Papadopulos, ... Oncogene 37 (4), 489-501, 2018 | 45 | 2018 |
Growth hormone and cell growth MJ Waters, AJ Brooks Developmental Biology of GH Secretion, Growth and Treatment 23, 86-95, 2012 | 43 | 2012 |
Growth hormone receptor: structure function relationships MJ Waters, AJ Brooks Hormone research in paediatrics 76 (Suppl. 1), 12-16, 2011 | 43 | 2011 |