WNT1-inducible signaling protein–1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis M Königshoff, M Kramer, N Balsara, J Wilhelm, OV Amarie, A Jahn, ... The Journal of clinical investigation 119 (4), 772-787, 2009 | 623 | 2009 |
Functional Wnt signaling is increased in idiopathic pulmonary fibrosis M Königshoff, N Balsara, EM Pfaff, M Kramer, I Chrobak, W Seeger, ... PloS one 3 (5), e2142, 2008 | 575 | 2008 |
Shared and distinct mechanisms of fibrosis JHW Distler, AH Györfi, M Ramanujam, ML Whitfield, M Königshoff, ... Nature Reviews Rheumatology 15 (12), 705-730, 2019 | 447 | 2019 |
Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis M Strunz, LM Simon, M Ansari, JJ Kathiriya, I Angelidis, CH Mayr, ... Nature communications 11 (1), 3559, 2020 | 436 | 2020 |
Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury CJ Scotton, MA Krupiczojc, M Königshoff, PF Mercer, YCG Lee, ... The Journal of clinical investigation 119 (9), 2550-2563, 2009 | 379 | 2009 |
Hallmarks of the ageing lung S Meiners, O Eickelberg, M Königshoff European Respiratory Journal 45 (3), 807-827, 2015 | 341 | 2015 |
WNT signaling in lung disease: a failure or a regeneration signal? M Königshoff, O Eickelberg American journal of respiratory cell and molecular biology 42 (1), 21-31, 2010 | 330 | 2010 |
Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo M Lehmann, M Korfei, K Mutze, S Klee, W Skronska-Wasek, HN Alsafadi, ... European Respiratory Journal 50 (2), 2017 | 327 | 2017 |
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ... Nature medicine 27 (3), 546-559, 2021 | 308 | 2021 |
An official American Thoracic Society workshop report: use of animal models for the preclinical assessment of potential therapies for pulmonary fibrosis RG Jenkins, BB Moore, RC Chambers, O Eickelberg, M Königshoff, ... American journal of respiratory cell and molecular biology 56 (5), 667-679, 2017 | 308 | 2017 |
Protease-Mediated Release of Chemotherapeutics from Mesoporous Silica Nanoparticles to ex Vivo Human and Mouse Lung Tumors SH van Rijt, DA Bölükbas, C Argyo, S Datz, M Lindner, O Eickelberg, ... ACS nano 9 (3), 2377-2389, 2015 | 217 | 2015 |
The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets HA Baarsma, M Königshoff, R Gosens Pharmacology & therapeutics 138 (1), 66-83, 2013 | 209 | 2013 |
An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices HN Alsafadi, CA Staab-Weijnitz, M Lehmann, M Lindner, B Peschel, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (6 …, 2017 | 203 | 2017 |
Activation of the WNT/β-catenin pathway attenuates experimental emphysema N Kneidinger, AO Yildirim, J Callegari, S Takenaka, MM Stein, ... American journal of respiratory and critical care medicine 183 (6), 723-733, 2011 | 203 | 2011 |
Lung ageing and COPD: is there a role for ageing in abnormal tissue repair? CA Brandsma, M de Vries, R Costa, RR Woldhuis, M Königshoff, ... European Respiratory Review 26 (146), 2017 | 200 | 2017 |
Extracellular‐matrix‐reinforced bioinks for 3D bioprinting human tissue MM De Santis, HN Alsafadi, S Tas, DA Bölükbas, S Prithiviraj, ... Advanced materials 33 (3), 2005476, 2021 | 194 | 2021 |
WNT/β-catenin signaling induces IL-1β expression by alveolar epithelial cells in pulmonary fibrosis V Aumiller, N Balsara, J Wilhelm, A Günther, M Königshoff American journal of respiratory cell and molecular biology 49 (1), 96-104, 2013 | 194 | 2013 |
‘WNT-er is coming’: WNT signalling in chronic lung diseases HA Baarsma, M Königshoff Thorax 72 (8), 746-759, 2017 | 182 | 2017 |
Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD HA Baarsma, W Skronska-Wasek, K Mutze, F Ciolek, DE Wagner, ... Journal of Experimental Medicine 214 (1), 143-163, 2017 | 174 | 2017 |
Transgelin is a direct target of TGF‐β/Smad3‐dependent epithelial cell migration in lung fibrosis H Yu, M Königshoff, A Jayachandran, D Handley, W Seeger, N Kaminski, ... The FASEB Journal 22 (6), 1778-1789, 2008 | 174 | 2008 |