Sphingolipid metabolism and neutral sphingomyelinases MV Airola, YA Hannun Sphingolipids: Basic science and drug development, 57-76, 2013 | 237 | 2013 |
Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes AA Shamseddine, MV Airola, YA Hannun Advances in biological regulation 57, 24-41, 2015 | 215 | 2015 |
Structure of concatenated HAMP domains provides a mechanism for signal transduction MV Airola, KJ Watts, AM Bilwes, BR Crane Structure 18 (4), 436-448, 2010 | 156 | 2010 |
How lipid droplets “TAG” along: Glycerolipid synthetic enzymes and lipid storage H Wang, MV Airola, K Reue Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017 | 115 | 2017 |
Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation MV Airola, P Shanbhogue, AA Shamseddine, KE Guja, CE Senkal, ... Proceedings of the National Academy of Sciences 114 (28), E5549-E5558, 2017 | 91 | 2017 |
P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest AA Shamseddine, CJ Clarke, B Carroll, MV Airola, S Mohammed, A Rella, ... Cell death & disease 6 (10), e1947-e1947, 2015 | 72 | 2015 |
HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors MV Airola, N Sukomon, D Samanta, PP Borbat, JH Freed, KJ Watts, ... PLoS biology 11 (2), e1001479, 2013 | 68 | 2013 |
Co-expression of ferrochelatase allows for complete heme incorporation into recombinant proteins produced in E. coli J Sudhamsu, M Kabir, MV Airola, BA Patel, SR Yeh, DL Rousseau, ... Protein expression and purification 73 (1), 78-82, 2010 | 64 | 2010 |
Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling MV Airola, D Huh, N Sukomon, J Widom, R Sircar, PP Borbat, JH Freed, ... Journal of molecular biology 425 (5), 886-901, 2013 | 59 | 2013 |
Heme binding to the mammalian circadian clock protein period 2 is nonspecific MV Airola, J Du, JH Dawson, BR Crane Biochemistry 49 (20), 4327-4338, 2010 | 52 | 2010 |
Structural basis for ceramide recognition and hydrolysis by human neutral ceramidase MV Airola, WJ Allen, MJ Pulkoski-Gross, LM Obeid, RC Rizzo, YA Hannun Structure 23 (8), 1482-1491, 2015 | 47 | 2015 |
Crystal structure of a lipin/Pah phosphatidic acid phosphatase VI Khayyo, RM Hoffmann, H Wang, JA Bell, JE Burke, K Reue, MV Airola Nature communications 11 (1), 1309, 2020 | 40 | 2020 |
Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80 X Chen, R Gaglione, T Leong, L Bednor, T de Los Santos, E Luk, M Airola, ... PLoS genetics 14 (11), e1007832, 2018 | 38 | 2018 |
Crystal structure of human PLD1 provides insight into activation by PI(4,5)P2 and RhoA FZ Bowling, CM Salazar, JA Bell, TS Huq, MA Frohman, MV Airola Nature chemical biology 16 (4), 400-407, 2020 | 34 | 2020 |
Structure and regulation of human phospholipase D FZ Bowling, MA Frohman, MV Airola Advances in biological regulation 79, 100783, 2021 | 29 | 2021 |
Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy N Lahrouchi, AV Postma, CM Salazar, M Daniel, F Tjong, L Piherová, ... The Journal of Clinical Investigation 131 (5), 2021 | 20 | 2021 |
PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport GE Miner, CM So, W Edwards, JV Ragusa, JT Wine, DW Gutierrez, ... Developmental Cell 58 (14), 1250-1265. e6, 2023 | 19 | 2023 |
Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation YM Choi, D Ajjaji, KD Fleming, PP Borbat, ML Jenkins, BE Moeller, ... Nature Communications 14 (1), 3204, 2023 | 18 | 2023 |
Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents N Pereira de Sa, A Taouil, J Kim, T Clement, RM Hoffmann, JE Burke, ... Nature communications 12 (1), 5885, 2021 | 17 | 2021 |
Quantification of 3-ketodihydrosphingosine using HPLC-ESI-MS/MS to study SPT activity in yeast Saccharomyces cerevisiae [S] J Ren, J Snider, MV Airola, A Zhong, NA Rana, LM Obeid, YA Hannun Journal of Lipid Research 59 (1), 162-170, 2018 | 17 | 2018 |