A genome-wide CRISPR screen identifies ZCCHC14 as a host factor required for hepatitis B surface antigen production A Hyrina, C Jones, D Chen, S Clarkson, N Cochran, P Feucht, G Hoffman, ... Cell Reports 29 (10), 2970-2978. e6, 2019 | 53 | 2019 |
Treatment-induced viral cure of hepatitis C virus-infected patients involves a dynamic interplay among three important molecular players in lipid homeostasis: circulating … A Hyrina, AD Olmstead, P Steven, M Krajden, E Tam, F Jean EBioMedicine 23, 68-78, 2017 | 39 | 2017 |
Human Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P) regulates cytoplasmic lipid droplet abundance: A potential target for indirect-acting anti-dengue virus agents A Hyrina, F Meng, SJ McArthur, S Eivemark, IR Nabi, F Jean PLoS One 12 (3), e0174483, 2017 | 37 | 2017 |
First crystal structure of a nonstructural hepatitis E viral protein identifies a putative novel zinc-binding protein A Proudfoot, A Hyrina, M Holdorf, AO Frank, D Bussiere Journal of virology 93 (13), 10.1128/jvi. 00170-19, 2019 | 20 | 2019 |
Hepatitis D virus interferes with hepatitis B virus RNA production via interferon-dependent and-independent mechanisms J Lucifora, D Alfaiate, C Pons, M Michelet, R Ramirez, F Fusil, F Amirache, ... Journal of Hepatology 78 (5), 958-970, 2023 | 15 | 2023 |
A polyomavirus peptide binds to the capsid VP1 pore and has potent antiviral activity against BK and JC polyomaviruses JR Kane, S Fong, J Shaul, A Frommlet, AO Frank, M Knapp, DE Bussiere, ... Elife 9, e50722, 2020 | 11 | 2020 |
Characterization of a novel capsid assembly modulator for the treatment of chronic hepatitis b virus infection D Burdette, A Hyrina, Z Song, RK Beran, T Cheung, S Gilmore, ... Antimicrobial Agents and Chemotherapy 67 (1), e01348-22, 2023 | 10 | 2023 |
Targeting lipid biosynthesis pathways for hepatitis B virus cure A Hyrina, D Burdette, Z Song, R Ramirez, A Okesli-Armlovich, ... Plos one 17 (8), e0270273, 2022 | 9 | 2022 |
A genome-wide CRISPR screen identifies ZCCHC14 as a host factor required for hepatitis B surface antigen production. Cell Rep 29: 2970–2978 A Hyrina, C Jones, D Chen, S Clarkson, N Cochran, P Feucht, G Hoffman, ... | 5 | 2019 |
An insect viral protein disrupts stress granule formation in mammalian cells J Sadasivan, A Hyrina, R DaSilva, E Jan Journal of Molecular Biology 435 (16), 168042, 2023 | 2 | 2023 |
Selective depletion of HBV-infected hepatocytes by class A capsid assembly modulators requires high levels of intrahepatic HBV core protein D Kornyeyev, Z Song, S Eng, C Soulette, R Ramirez, J Tang, Q Yue, ... Antimicrobial Agents and Chemotherapy, e00420-24, 2024 | 1 | 2024 |
Elevated plasma miR-24, miR-223, and PCSK9 levels in hepatitis C-infected patients who achieve a treatment-based viral cure A Hyrina, A Olmstead, P Steven, M Krajden, E Tam, F Jean HEPATOLOGY 63 (1 SUPP), 735A-735A, 2016 | 1 | 2016 |
Intrahepatic transcriptional profiling demonstrates preclinical models of chronic hepatitis B resemble different stages of natural history in humans R Ramirez, A Hyrina, R Beran, S Daffis, S Gilmore, D Kang, NA Montanari, ... Journal of Hepatology 77, S251, 2022 | | 2022 |
Statin use and surface antigen loss in patients with chronic hepatitis B S Iqbal, R Li, S Suthram, J Wallin, J Trevaskis, A Hyrina, S Fletcher, ... Journal of Hepatology 77 (S1), S119-S388, 2022 | | 2022 |
EXPLORING INHIBITION OF DE NOVO LIPOGENESIS TO CURE HEPATITIS B A Hyrina, D Burdette, A Okesli-Armlovich, A Vijayakumar, J Bates, ... HEPATOLOGY 74, 506A-507A, 2021 | | 2021 |
eLive revised manuscript: A POLYOMAVIRUS PEPTIDE BINDS TO THE CAPSID VP1 PORE AND HAS POTENT ANTIVIRAL ACTIVITY AGAINST BK AND JC POLYOMAVIRUSES C Wartchow, J Kane, J Shaul, A Frank, M Knapp, D Bussiere, E Ornelas, ... ELife. 9, 2020 | | 2020 |
ZCCHC14 is a novel host factor that is required for Hepatitis B virus RNA polyadenylation A Hyrina, M Holdorf, C Jones Cell reports 29 (10), 2970-2978, 2019 | | 2019 |
A29 THE MOLECULAR INTERPLAY BETWEEN CIRCULATING MIR-24, MIR-223, AND PCSK9 IN HEPATITIS C-INFECTED PATIENTS WHO ACHIEVE A TREATMENT-BASED VIRAL CURE A Hyrina, A Olmstead, P Steven, M Krajden, E Tam, F Jean Journal of the Canadian Association of Gastroenterology 1 (suppl_1), 53-54, 2018 | | 2018 |
Investigating the hepatitis C virus and dengue virus interactions with host lipid pathways: from circulating human microRNAs to lipid modulating agents A Hyrina University of British Columbia, 2016 | | 2016 |