Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1 G Levkowitz, H Waterman, SA Ettenberg, M Katz, AY Tsygankov, I Alroy, ... Molecular cell 4 (6), 1029-1040, 1999 | 1258 | 1999 |
The Cbl family proteins: ring leaders in regulation of cell signaling G Swaminathan, AY Tsygankov Journal of cellular physiology 209 (1), 21-43, 2006 | 359 | 2006 |
The Src family of tyrosine protein kinases in hemopoietic signal transduction JB Bolen, RB Rowley, C Spana, AY Tsygankov The FASEB journal 6 (15), 3403-3409, 1992 | 314 | 1992 |
Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells EA Feshchenko, WY Langdon, AY Tsygankov Journal of Biological Chemistry 273 (14), 8323-8331, 1998 | 203 | 1998 |
Activation of tyrosine kinase p60fyn following T cell antigen receptor cross-linking. AY Tsygankov, BM Bröker, J Fargnoli, JA Ledbetter, JB Bolen Journal of Biological Chemistry 267 (26), 18259-18262, 1992 | 172 | 1992 |
Beyond the RING: CBL proteins as multivalent adapters AY Tsygankov, AM Teckchandani, EA Feshchenko, G Swaminathan Oncogene 20 (44), 6382-6402, 2001 | 157 | 2001 |
The Product of the Herpesvirus saimiri Open Reading Frame 1 (Tip) Interacts with T Cell-specific Kinase p56lck in Transformed Cells (∗) B Biesinger, AY Tsygankov, H Fickenscher, F Emmrich, B Fleckenstein, ... Journal of Biological Chemistry 270 (9), 4729-4734, 1995 | 151 | 1995 |
TULA: an SH3-and UBA-containing protein that binds to c-Cbl and ubiquitin EA Feshchenko, EV Smirnova, G Swaminathan, AM Teckchandani, ... Oncogene 23 (27), 4690-4706, 2004 | 106 | 2004 |
Specific association of tyrosine-phosphorylated c-Cbl with Fyn tyrosine kinase in T cells AY Tsygankov, S Mahajan, JE Fincke, JB Bolen Journal of Biological Chemistry 271 (43), 27130-27137, 1996 | 106 | 1996 |
P2Y12 Receptor Modulates Sepsis-Induced Inflammation E Liverani, MC Rico, AY Tsygankov, LE Kilpatrick, SP Kunapuli Arteriosclerosis, thrombosis, and vascular biology 36 (5), 961-971, 2016 | 100 | 2016 |
Immortalization of human T cell clones by Herpesvirus saimiri. Signal transduction analysis reveals functional CD3, CD4, and IL-2 receptors. BM Bröker, AY Tsygankov, I Müller-Fleckenstein, AH Guse, NA Chitaev, ... Journal of immunology (Baltimore, Md.: 1950) 151 (3), 1184-1192, 1993 | 100 | 1993 |
LPS-induced systemic inflammation is more severe in P2Y12 null mice E Liverani, MC Rico, L Yaratha, AY Tsygankov, LE Kilpatrick, SP Kunapuli Journal of leukocyte biology 95 (2), 313-323, 2014 | 95 | 2014 |
Non-receptor protein tyrosine kinases AY Tsygankov Front Biosci 8 (6), S595-S635, 2003 | 92 | 2003 |
Selective Activation of T Cell Kinase p56lck by Herpesvirus saimiri Protein Tip (∗) N Wiese, AY Tsygankov, U Klauenberg, JB Bolen, B Fleischer, BM Bröker Journal of Biological Chemistry 271 (2), 847-852, 1996 | 87 | 1996 |
Rapid ubiquitination of Syk following GPVI activation in platelets CA Dangelmaier, PG Quinter, J Jin, AY Tsygankov, SP Kunapuli, ... Blood 105 (10), 3918-3924, 2005 | 85 | 2005 |
Cbl-mediated ubiquitinylation and negative regulation of Vav Y Miura-Shimura, L Duan, NL Rao, AL Reddi, H Shimura, R Rottapel, ... Journal of Biological Chemistry 278 (40), 38495-38504, 2003 | 79 | 2003 |
A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets DH Thomas, TM Getz, TN Newman, CA Dangelmaier, N Carpino, ... Blood, The Journal of the American Society of Hematology 116 (14), 2570-2578, 2010 | 74 | 2010 |
TULA proteins regulate activity of the protein tyrosine kinase Syk R Agrawal, N Carpino, A Tsygankov Journal of cellular biochemistry 104 (3), 953-964, 2008 | 67 | 2008 |
Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts EA Feshchenko, SK Shore, AY Tsygankov Oncogene 18 (25), 3703-3715, 1999 | 67 | 1999 |
Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate X Chen, L Ren, S Kim, N Carpino, JL Daniel, SP Kunapuli, AY Tsygankov, ... Journal of biological chemistry 285 (41), 31268-31276, 2010 | 64 | 2010 |