A single recurrent mutation in the 5′-UTR of IFITM5 causes osteogenesis imperfecta type V TJ Cho, KE Lee, SK Lee, SJ Song, KJ Kim, D Jeon, G Lee, HN Kim, ... The American Journal of Human Genetics 91 (2), 343-348, 2012 | 287 | 2012 |
FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation SM Bartell, HN Kim, E Ambrogini, L Han, S Iyer, S Serra Ucer, ... Nature communications 5 (1), 3773, 2014 | 244 | 2014 |
Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity Y He, X Zhang, J Chang, HN Kim, P Zhang, Y Wang, S Khan, X Liu, ... Nature communications 11 (1), 1996, 2020 | 183 | 2020 |
DNA damage and senescence in osteoprogenitors expressing Osx1 may cause their decrease with age HN Kim, J Chang, L Shao, LI Han, S Iyer, SC Manolagas, CA O'Brien, ... Aging cell 16 (4), 693-703, 2017 | 164 | 2017 |
Old age causes de novo intracortical bone remodeling and porosity in mice M Piemontese, M Almeida, AG Robling, HN Kim, J Xiong, JD Thostenson, ... JCI insight 2 (17), 2017 | 161 | 2017 |
Reciprocal cross‐talk between RANKL and interferon‐γ–inducible protein 10 is responsible for bone‐erosive experimental arthritis HB Kwak, H Ha, HN Kim, JH Lee, HS Kim, S Lee, HM Kim, JY Kim, ... Arthritis & Rheumatism 58 (5), 1332-1342, 2008 | 153 | 2008 |
Epigallocatechin-3-gallate inhibits osteoclastogenesis by down-regulating c-Fos expression and suppressing the nuclear factor-κB signal JH Lee, H Jin, HE Shim, HN Kim, H Ha, ZH Lee Molecular pharmacology 77 (1), 17-25, 2010 | 147 | 2010 |
Sirtuin1 (Sirt1) promotes cortical bone formation by preventing β-catenin sequestration by FoxO transcription factors in osteoblast progenitors S Iyer, L Han, SM Bartell, HN Kim, I Gubrij, R de Cabo, CA O'Brien, ... Journal of Biological Chemistry 289 (35), 24069-24078, 2014 | 130 | 2014 |
α-Lipoic acid inhibits inflammatory bone resorption by suppressing prostaglandin E2 synthesis H Ha, JH Lee, HN Kim, HM Kim, HB Kwak, S Lee, HH Kim, ZH Lee The Journal of Immunology 176 (1), 111-117, 2006 | 124 | 2006 |
CXCL10 promotes osteolytic bone metastasis by enhancing cancer outgrowth and osteoclastogenesis JH Lee, HN Kim, KO Kim, WJ Jin, S Lee, HH Kim, H Ha, ZH Lee Cancer research 72 (13), 3175-3186, 2012 | 122 | 2012 |
The effects of aging and sex steroid deficiency on the murine skeleton are independent and mechanistically distinct S Ucer, S Iyer, HN Kim, L Han, C Rutlen, K Allison, JD Thostenson, ... Journal of Bone and Mineral Research 32 (3), 560-574, 2017 | 115 | 2017 |
Sirtuin1 suppresses osteoclastogenesis by deacetylating FoxOs HN Kim, L Han, S Iyer, R de Cabo, H Zhao, CA O'Brien, SC Manolagas, ... Molecular endocrinology 29 (10), 1498-1509, 2015 | 103 | 2015 |
Tanshinone IIA inhibits osteoclast differentiation through down-regulation of c-Fos and NFATc1 HB Kwak, D Yang, H Ha, JH Lee, HN Kim, ER Woo, S Lee, HH Kim, ... Experimental & molecular medicine 38 (3), 256-264, 2006 | 89 | 2006 |
Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling JH Lee, HN Kim, D Yang, K Jung, HM Kim, HH Kim, H Ha, ZH Lee Journal of Biological Chemistry 284 (20), 13725-13734, 2009 | 83 | 2009 |
The effects of androgens on murine cortical bone do not require AR or ERα signaling in osteoblasts and osteoclasts S Ucer, S Iyer, SM Bartell, M Martin‐Millan, L Han, HN Kim, RS Weinstein, ... Journal of Bone and Mineral Research 30 (7), 1138-1149, 2015 | 82 | 2015 |
Elimination of senescent osteoclast progenitors has no effect on the age‐associated loss of bone mass in mice HN Kim, J Chang, S Iyer, L Han, J Campisi, SC Manolagas, D Zhou, ... Aging cell 18 (3), e12923, 2019 | 71 | 2019 |
Estrogens decrease osteoclast number by attenuating mitochondria oxidative phosphorylation and ATP production in early osteoclast precursors HN Kim, F Ponte, I Nookaew, S Ucer Ozgurel, A Marques-Carvalho, S Iyer, ... Scientific reports 10 (1), 11933, 2020 | 69 | 2020 |
α-Tocotrienol inhibits osteoclastic bone resorption by suppressing RANKL expression and signaling and bone resorbing activity H Ha, JH Lee, HN Kim, ZH Lee Biochemical and biophysical research communications 406 (4), 546-551, 2011 | 67 | 2011 |
Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence HN Kim, J Xiong, RS MacLeod, S Iyer, Y Fujiwara, KM Cawley, L Han, ... JCI insight 5 (19), 2020 | 66 | 2020 |
Non-nuclear–initiated actions of the estrogen receptor protect cortical bone mass SM Bartell, L Han, H Kim, SH Kim, JA Katzenellenbogen, ... Molecular endocrinology 27 (4), 649-656, 2013 | 62 | 2013 |