Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells C Campbell, PT McKenney, D Konstantinovsky, OI Isaeva, M Schizas, ... Nature 581 (7809), 475-479, 2020 | 542 | 2020 |
A metabolic pathway for bile acid dehydroxylation by the gut microbiome M Funabashi, TL Grove, M Wang, Y Varma, ME McFadden, LC Brown, ... Nature 582 (7813), 566-570, 2020 | 349 | 2020 |
Two Separate Gene Clusters Encode the Biosynthetic Pathway for the Meroterpenoids Austinol and Dehydroaustinol in Aspergillus nidulans HC Lo, R Entwistle, CJ Guo, M Ahuja, E Szewczyk, JH Hung, YM Chiang, ... Journal of the American Chemical Society 134 (10), 4709-4720, 2012 | 266 | 2012 |
Discovery of reactive microbiota-derived metabolites that inhibit host proteases CJ Guo, FY Chang, TP Wyche, KM Backus, TM Acker, M Funabashi, ... Cell 168 (3), 517-526. e18, 2017 | 220 | 2017 |
Prototype of an intertwined secondary-metabolite supercluster P Wiemann, CJ Guo, JM Palmer, R Sekonyela, CCC Wang, NP Keller Proceedings of the National Academy of Sciences 110 (42), 17065-17070, 2013 | 200 | 2013 |
Microbial transplantation with human gut commensals containing CutC is sufficient to transmit enhanced platelet reactivity and thrombosis potential SM Skye, W Zhu, KA Romano, CJ Guo, Z Wang, X Jia, J Kirsop, B Haag, ... Circulation research 123 (10), 1164-1176, 2018 | 143 | 2018 |
Depletion of microbiome-derived molecules in the host using Clostridium genetics CJ Guo, BM Allen, KJ Hiam, D Dodd, W Van Treuren, S Higginbottom, ... Science 366 (6471), eaav1282, 2019 | 132 | 2019 |
Microbial metabolomics in open microscale platforms LJ Barkal*, AB Theberge*, CJ Guo*, J Spraker, L Rappert, J Berthier, ... Nature Communications 7, 2016 | 105 | 2016 |
Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis CJ Guo, HH Yeh, YM Chiang, JF Sanchez, SL Chang, KS Bruno, ... Journal of the American Chemical Society 135 (19), 7205-7213, 2013 | 95 | 2013 |
Molecular Genetic Characterization of a Cluster in A. terreus for Biosynthesis of the Meroterpenoid Terretonin CJ Guo, BP Knox, YM Chiang, HC Lo, JF Sanchez, KH Lee, BR Oakley, ... Organic letters 14 (22), 5684-5687, 2012 | 93 | 2012 |
Discovery of McrA, a master regulator of Aspergillus secondary metabolism CE Oakley, M Ahuja, WW Sun, R Entwistle, T Akashi, J Yaegashi, CJ Guo, ... Molecular microbiology 103 (2), 347-365, 2017 | 80 | 2017 |
Genetic manipulation of gut microbes enables single-gene interrogation in a complex microbiome WB Jin, TT Li, D Huo, S Qu, XV Li, M Arifuzzaman, SF Lima, HQ Shi, ... Cell 185 (3), 547-562. e22, 2022 | 79 | 2022 |
Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation M Arifuzzaman, TH Won, TT Li, H Yano, S Digumarthi, AF Heras, W Zhang, ... Nature 611 (7936), 578-584, 2022 | 77 | 2022 |
Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites E Berthier, FY Lim, Q Deng, CJ Guo, DP Kontoyiannis, CCC Wang, ... PLoS pathogens 9 (4), e1003289, 2013 | 75 | 2013 |
Recent advances in genome mining of secondary metabolites in Aspergillus terreus CJ Guo, CCC Wang Frontiers in Microbiology 5, 717, 2014 | 73 | 2014 |
Transferable immunoglobulin A–Coated Odoribacter splanchnicus in responders to fecal microbiota transplantation for ulcerative colitis limits colonic inflammation SF Lima, L Gogokhia, M Viladomiu, L Chou, G Putzel, WB Jin, S Pires, ... Gastroenterology 162 (1), 166-178, 2022 | 71 | 2022 |
Adherent-invasive E. coli metabolism of propanediol in Crohn’s disease regulates phagocytes to drive intestinal inflammation M Viladomiu, ML Metz, SF Lima, WB Jin, L Chou, CJ Guo, GE Diehl, ... Cell host & microbe 29 (4), 607-619. e8, 2021 | 67 | 2021 |
Application of an Efficient Gene Targeting System Linking Secondary Metabolites to their Biosynthetic Genes in Aspergillus terreus CJ Guo, BP Knox, JF Sanchez, YM Chiang, KS Bruno, CCC Wang Organic letters 15 (14), 3562-3565, 2013 | 65 | 2013 |
Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection W Zhang, M Lyu, NJ Bessman, Z Xie, M Arifuzzaman, H Yano, ... Cell 185 (22), 4170-4189. e20, 2022 | 57 | 2022 |
Spatial regulation of a common precursor from two distinct genes generates metabolite diversity CJ Guo, WW Sun, KS Bruno, BR Oakley, NP Keller, CCC Wang Chemical science 6 (10), 5913-5921, 2015 | 41 | 2015 |