关注
Cory Ayres
Cory Ayres
Assistant Research Professor, University of Notre Dame
在 nd.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity
F Duan, J Duitama, S Al Seesi, CM Ayres, SA Corcelli, AP Pawashe, ...
Journal of Experimental Medicine 211 (11), 2231-2248, 2014
4462014
Peptide modulation of class I major histocompatibility complex protein molecular flexibility and the implications for immune recognition
WF Hawse, BE Gloor, CM Ayres, K Kho, E Nuter, BM Baker
Journal of Biological Chemistry 288 (34), 24372-24381, 2013
612013
Structural dissimilarity from self drives neoepitope escape from immune tolerance
JR Devlin, JA Alonso, CM Ayres, GLJ Keller, S Bobisse, CW Vander Kooi, ...
Nature chemical biology 16 (11), 1269-1276, 2020
572020
Improving T cell receptor on-target specificity via structure-guided design
LM Hellman, KC Foley, NK Singh, JA Alonso, TP Riley, JR Devlin, ...
Molecular Therapy 27 (2), 300-313, 2019
542019
Dynamically driven allostery in MHC proteins: Peptide-dependent tuning of class I MHC global flexibility
CM Ayres, ET Abualrous, A Bailey, C Abraham, LM Hellman, SA Corcelli, ...
Frontiers in immunology 10, 966, 2019
492019
Peptide and peptide-dependent motions in MHC proteins: immunological implications and biophysical underpinnings
CM Ayres, SA Corcelli, BM Baker
Frontiers in Immunology 8, 935, 2017
462017
Differential utilization of binding loop flexibility in T cell receptor ligand selection and cross-reactivity
CM Ayres, DR Scott, SA Corcelli, BM Baker
Scientific reports 6 (1), 25070, 2016
292016
A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces
TP Riley, CM Ayres, LM Hellman, NK Singh, M Cosiano, JM Cimons, ...
Protein Engineering, Design and Selection 29 (12), 595-606, 2016
262016
Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner
AR Smith, JA Alonso, CM Ayres, NK Singh, LM Hellman, BM Baker
Proceedings of the National Academy of Sciences 118 (4), e2018125118, 2021
242021
Geometrical characterization of T cell receptor binding modes reveals class‐specific binding to maximize access to antigen
NK Singh, ET Abualrous, CM Ayres, F Noé, R Gowthaman, BG Pierce, ...
Proteins: Structure, Function, and Bioinformatics 88 (3), 503-513, 2020
232020
Modeling sequence-dependent peptide fluctuations in immunologic recognition
CM Ayres, TP Riley, SA Corcelli, BM Baker
Journal of chemical information and modeling 57 (8), 1990-1998, 2017
172017
Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes
JM Custodio, CM Ayres, TJ Rosales, CA Brambley, AG Arbuiso, ...
Proceedings of the National Academy of Sciences 120 (51), e2312057120, 2023
82023
The energetic landscape of catch bonds in TCR interfaces
CM Ayres, SA Corcelli, BM Baker
The Journal of Immunology 211 (3), 325-332, 2023
42023
Peptide-dependent tuning of major histocompatibility complex motional properties and the consequences for cellular immunity
CM Ayres, BM Baker
Current opinion in immunology 76, 102184, 2022
42022
Dynamic allostery controls the peptide sensitivity of the Ly49C natural killer receptor
J Ma, CM Ayres, LM Hellman, JR Devlin, BM Baker
Journal of Biological Chemistry 296, 2021
42021
Enhanced T cell receptor specificity through framework engineering
AM Rosenberg, CM Ayres, AV Medina-Cucurella, TA Whitehead, ...
Frontiers in Immunology 15, 1345368, 2024
12024
Modeling the Binding Mechanism of a T Cell Receptor and Major Histocompatibility Complex
E Groth, CM Ayres, BM Baker, SA Corcelli
Biophysical Journal 118 (3), 245a, 2020
12020
Dynamic allostery in the peptide/MHC complex enables TCR neoantigen selectivity
J Ma, CM Ayres, CA Brambley, SS Chandran, TJ Rosales, SA Corcelli, ...
Research Square, 2024
2024
Human versus mouse Beta 2 microglobulin alters TCR antigen recognition kinetics with mouse MHCI
VJ Rase, EM Kolawole, B Liu, CM Ayres, J Rogers, K Salaita, BM Baker, ...
The Journal of Immunology 210 (1_Supplement), 221.30-221.30, 2023
2023
Biomolecule design model and uses thereof
BM Baker, T Riley, C Ayres
US Patent App. 16/090,766, 2019
2019
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