Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity F Duan, J Duitama, S Al Seesi, CM Ayres, SA Corcelli, AP Pawashe, ... Journal of Experimental Medicine 211 (11), 2231-2248, 2014 | 446 | 2014 |
Peptide modulation of class I major histocompatibility complex protein molecular flexibility and the implications for immune recognition WF Hawse, BE Gloor, CM Ayres, K Kho, E Nuter, BM Baker Journal of Biological Chemistry 288 (34), 24372-24381, 2013 | 61 | 2013 |
Structural dissimilarity from self drives neoepitope escape from immune tolerance JR Devlin, JA Alonso, CM Ayres, GLJ Keller, S Bobisse, CW Vander Kooi, ... Nature chemical biology 16 (11), 1269-1276, 2020 | 57 | 2020 |
Improving T cell receptor on-target specificity via structure-guided design LM Hellman, KC Foley, NK Singh, JA Alonso, TP Riley, JR Devlin, ... Molecular Therapy 27 (2), 300-313, 2019 | 54 | 2019 |
Dynamically driven allostery in MHC proteins: Peptide-dependent tuning of class I MHC global flexibility CM Ayres, ET Abualrous, A Bailey, C Abraham, LM Hellman, SA Corcelli, ... Frontiers in immunology 10, 966, 2019 | 49 | 2019 |
Peptide and peptide-dependent motions in MHC proteins: immunological implications and biophysical underpinnings CM Ayres, SA Corcelli, BM Baker Frontiers in Immunology 8, 935, 2017 | 46 | 2017 |
Differential utilization of binding loop flexibility in T cell receptor ligand selection and cross-reactivity CM Ayres, DR Scott, SA Corcelli, BM Baker Scientific reports 6 (1), 25070, 2016 | 29 | 2016 |
A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces TP Riley, CM Ayres, LM Hellman, NK Singh, M Cosiano, JM Cimons, ... Protein Engineering, Design and Selection 29 (12), 595-606, 2016 | 26 | 2016 |
Structurally silent peptide anchor modifications allosterically modulate T cell recognition in a receptor-dependent manner AR Smith, JA Alonso, CM Ayres, NK Singh, LM Hellman, BM Baker Proceedings of the National Academy of Sciences 118 (4), e2018125118, 2021 | 24 | 2021 |
Geometrical characterization of T cell receptor binding modes reveals class‐specific binding to maximize access to antigen NK Singh, ET Abualrous, CM Ayres, F Noé, R Gowthaman, BG Pierce, ... Proteins: Structure, Function, and Bioinformatics 88 (3), 503-513, 2020 | 23 | 2020 |
Modeling sequence-dependent peptide fluctuations in immunologic recognition CM Ayres, TP Riley, SA Corcelli, BM Baker Journal of chemical information and modeling 57 (8), 1990-1998, 2017 | 17 | 2017 |
Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes JM Custodio, CM Ayres, TJ Rosales, CA Brambley, AG Arbuiso, ... Proceedings of the National Academy of Sciences 120 (51), e2312057120, 2023 | 8 | 2023 |
The energetic landscape of catch bonds in TCR interfaces CM Ayres, SA Corcelli, BM Baker The Journal of Immunology 211 (3), 325-332, 2023 | 4 | 2023 |
Peptide-dependent tuning of major histocompatibility complex motional properties and the consequences for cellular immunity CM Ayres, BM Baker Current opinion in immunology 76, 102184, 2022 | 4 | 2022 |
Dynamic allostery controls the peptide sensitivity of the Ly49C natural killer receptor J Ma, CM Ayres, LM Hellman, JR Devlin, BM Baker Journal of Biological Chemistry 296, 2021 | 4 | 2021 |
Enhanced T cell receptor specificity through framework engineering AM Rosenberg, CM Ayres, AV Medina-Cucurella, TA Whitehead, ... Frontiers in Immunology 15, 1345368, 2024 | 1 | 2024 |
Modeling the Binding Mechanism of a T Cell Receptor and Major Histocompatibility Complex E Groth, CM Ayres, BM Baker, SA Corcelli Biophysical Journal 118 (3), 245a, 2020 | 1 | 2020 |
Dynamic allostery in the peptide/MHC complex enables TCR neoantigen selectivity J Ma, CM Ayres, CA Brambley, SS Chandran, TJ Rosales, SA Corcelli, ... Research Square, 2024 | | 2024 |
Human versus mouse Beta 2 microglobulin alters TCR antigen recognition kinetics with mouse MHCI VJ Rase, EM Kolawole, B Liu, CM Ayres, J Rogers, K Salaita, BM Baker, ... The Journal of Immunology 210 (1_Supplement), 221.30-221.30, 2023 | | 2023 |
Biomolecule design model and uses thereof BM Baker, T Riley, C Ayres US Patent App. 16/090,766, 2019 | | 2019 |