Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition K Essafi-Benkhadir, A Refai, I Riahi, S Fattouch, H Karoui, M Essafi Biochemical and biophysical research communications 418 (1), 180-185, 2012 | 134 | 2012 |
The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells I Riahi-Chebbi, S Souid, H Othman, M Haoues, H Karoui, A Morel, ... Scientific Reports 9 (1), 195, 2019 | 127 | 2019 |
Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation K Essafi-Benkhadir, C Onesto, E Stebe, C Moroni, G Pagès Molecular biology of the cell 18 (11), 4648-4658, 2007 | 124 | 2007 |
A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast … P Griseri, C Bourcier, C Hieblot, K Essafi-Benkhadir, E Chamorey, ... Human molecular genetics 20 (23), 4556-4568, 2011 | 87 | 2011 |
Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor‐induced angiogenesis through cell cycle arrest, apoptosis induction and … O Zakraoui, C Marcinkiewicz, Z Aloui, H Othman, R Grépin, M Haoues, ... Molecular carcinogenesis 56 (1), 18-35, 2017 | 76 | 2017 |
Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells C Ellijimi, MB Hammouda, H Othman, W Moslah, J Jebali, HB Mabrouk, ... Biomedicine & Pharmacotherapy 101, 871-880, 2018 | 65 | 2018 |
Asteraceae Artemisia campestris and Artemisia herba-alba Essential Oils Trigger Apoptosis and Cell Cycle Arrest in Leishmania infantum Promastigotes Z Aloui, C Messaoud, M Haoues, N Neffati, I Bassoumi Jamoussi, ... Evidence‐Based Complementary and Alternative Medicine 2016 (1), 9147096, 2016 | 63 | 2016 |
Molecular cloning and functional expression of the alpha-scorpion toxin BotIII: pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels K Benkhadir, R Kharrat, S Cestèle, A Mosbah, H Rochat, M El Ayeb, ... Peptides 25 (2), 151-161, 2004 | 50 | 2004 |
Functional role of Kv1. 1 and Kv1. 3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides D Aissaoui, S Mlayah-Bellalouna, J Jebali, Z Abdelkafi-Koubaa, S Souid, ... International journal of biological macromolecules 111, 1146-1155, 2018 | 46 | 2018 |
Dual role of Sp3 transcription factor as an inducer of apoptosis and a marker of tumour aggressiveness K Essafi-Benkhadir, S Grosso, A Puissant, G Robert, M Essafi, M Deckert, ... PloS one 4 (2), e4478, 2009 | 46 | 2009 |
Mertensene, a halogenated monoterpene, induces G2/M cell cycle arrest and caspase dependent apoptosis of human colon adenocarcinoma HT29 cell line through the modulation of ERK … S Tarhouni-Jabberi, O Zakraoui, E Ioannou, I Riahi-Chebbi, M Haoues, ... Marine drugs 15 (7), 221, 2017 | 45 | 2017 |
Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity … MB Hammouda, I Riahi-Chebbi, S Souid, H Othman, Z Aloui, N Srairi-Abid, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (3), 600-614, 2018 | 31 | 2018 |
Lebein, a snake venom disintegrin, induces apoptosis in human melanoma cells MB Hammouda, MF Montenegro, L Sánchez-del-Campo, O Zakraoui, ... Toxins 8 (7), 206, 2016 | 30 | 2016 |
Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy I Riahi-Chebbi, M Haoues, M Essafi, O Zakraoui, S Fattouch, H Karoui, ... Cancer Cell International 16, 1-15, 2015 | 29 | 2015 |
Implication of the ERK pathway on the post-transcriptional regulation of VEGF mRNA stability K Essafi-Benkhadir, J Pouysségur, G Pagès MAP Kinase Signaling Protocols: Second Edition, 451-469, 2010 | 27 | 2010 |
Antimicrobial activities and mode of flavonoid actions A Thebti, A Meddeb, I Ben Salem, C Bakary, S Ayari, F Rezgui, ... Antibiotics 12 (2), 225, 2023 | 26 | 2023 |
Allium roseum L. extract exerts potent suppressive activities on chronic myeloid leukemia K562 cell viability through the inhibition of BCR-ABL, PI3K/Akt, and ERK1/2 pathways … S Souid, H Najjaa, I Riahi-Chebbi, M Haoues, M Neffati, I Arnault, J Auger, ... Nutrition and cancer 69 (1), 117-130, 2017 | 20 | 2017 |
Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A E Harigua-Souiai, YZ Abdelkrim, I Bassoumi-Jamoussi, O Zakraoui, ... PLoS Neglected Tropical Diseases 12 (1), e0006160, 2018 | 18 | 2018 |
AaHIV a sodium channel scorpion toxin inhibits the proliferation of DU145 prostate cancer cells R BenAissa, H Othman, C Villard, S Peigneur, S Mlayah-Bellalouna, ... Biochemical and biophysical research communications 521 (2), 340-346, 2020 | 17 | 2020 |
Interplay between Signaling Pathways and Tumor Microenvironment Components: A Paradoxical Role in Colorectal Cancer S Ben Hamouda, K Essafi-Benkhadir International journal of molecular sciences 24 (6), 5600, 2023 | 13 | 2023 |